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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,001–14,050 of 18,558 reactions from Rhea

4-CDP-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 3,4-cyclophosphate + CMP + H(+)
Direction not assertedBalancedRhea 68364
3-O-{beta-D-GlcA-(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP-alpha-D-xylose = 3-O-{(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n+1)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 68368
L-asparagine + pyruvate = 2-oxosuccinamate + L-alanine
Direction not assertedBalancedRhea 68372
L-asparagine + glyoxylate = 2-oxosuccinamate + glycine
Direction not assertedBalancedRhea 68376
3-hydroxypyruvate + L-asparagine = 2-oxosuccinamate + L-serine
Direction not assertedBalancedRhea 68380
L-tryptophyl-[protein] + (2E,6E)-farnesyl diphosphate = (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate

? Direction not asserted

Balance undeterminable

Rhea 68384

2 5,6-dihydroxyindole-2-carboxylate + O2 = 2 indole-5,6-quinone-2-carboxylate + 2 H2O

Left to rightBalancedRhea 68388

peracetic acid + H2O = acetate + H2O2 + H(+)

Direction not assertedBalancedRhea 68392

a percarboxylic acid + H2O = a carboxylate + H2O2 + H(+)

Direction not assertedBalance undeterminableRhea 68396

(2E,6E)-farnesyl diphosphate = gamma-gurjunene + diphosphate

Direction not assertedBalancedRhea 68400

(2R,3S)-iso(homo)2citrate + NAD(+) = 2-oxoheptanedioate + CO2 + NADH

Direction not assertedBalancedRhea 68404

(2R,3S)-iso(homo)3citrate + NAD(+) = 2-oxosuberate + CO2 + NADH

Direction not assertedBalancedRhea 68408

L-glutamate 5-semialdehyde + NADP(+) + H2O = L-glutamate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 68412

cis-(homo)2aconitate + H2O = (2R,3S)-iso(homo)2citrate

Direction not assertedBalancedRhea 68416

cis-(homo)3aconitate + H2O = (2R,3S)-iso(homo)3citrate

Direction not assertedBalancedRhea 68420

(3R)-3-hydroxy-10'-apo-beta-carotenal + O2 = 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + (3R)-hydroxy-beta-ionone

Left to rightBalancedRhea 68424

lutein + O2 = (3R,6R)-hydroxy-alpha-ionone + (3R)-3-hydroxy-10'-apo-beta-carotenal

Left to rightBalancedRhea 68428

lutein + O2 = (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + (3R)-hydroxy-beta-ionone

Left to rightBalancedRhea 68432

(3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 = (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial

Left to rightBalancedRhea 68436

beta-cryptoxanthin + O2 = all-trans-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone

Left to rightBalancedRhea 68440

5-cis-lycopene + O2 = 5-cis-10'-apo-lycopenal + (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one

Left to rightBalancedRhea 68444

13-cis-lycopene + O2 = 13-cis-10'-apo-lycopenal + (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one

Left to rightBalancedRhea 68448

all-trans-10'-apo-beta-carotenal + O2 = beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial

Left to rightBalancedRhea 68452

(S)-3-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O

Right to leftBalancedRhea 68456

a phenolic steroid + 3'-phosphoadenylyl sulfate = a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 68460

2-butyloctyl sulfate + H2O = 2-butyloctan-1-ol + sulfate + H(+)

Direction not assertedBalancedRhea 68464

(2Z,6Z)-farnesyl diphosphate = (E)-gamma-bisabolene + diphosphate

Direction not assertedBalancedRhea 68468

(2Z,6Z)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 68472

a (2R)-2-hydroperoxy fatty acid + H(+) = a fatty aldehyde + CO2 + H2O

Direction not assertedBalance undeterminableRhea 68476

(2R)-2-hydroperoxyhexadecanoate + H(+) = pentadecanal + CO2 + H2O

Direction not assertedBalancedRhea 68480

(2R)-2-hydroperoxydodecanoate + H(+) = undecanal + CO2 + H2O

Direction not assertedBalancedRhea 68484

(2R)-2-hydroperoxytetradecanoate + H(+) = tridecanal + CO2 + H2O

Direction not assertedBalancedRhea 68488

(2R,9Z,12Z)-2-hydroperoxyoctadecadienoate + H(+) = (8Z,11Z)-heptadecadienal + CO2 + H2O

Direction not assertedBalancedRhea 68492

(2R)-2-hydroperoxyoctadecanoate + H(+) = heptadecanal + CO2 + H2O

Direction not assertedBalancedRhea 68496

(2R,9Z)-2-hydroperoxyoctadecenoate + H(+) = (8Z)-heptadecenal + CO2 + H2O

Direction not assertedBalancedRhea 68500

(2Z,6Z)-farnesyl diphosphate = (Z)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68504

(2E,6E)-farnesyl diphosphate = (Z)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68508

(2Z,6Z)-farnesyl diphosphate = alpha-acoradiene + diphosphate

Direction not assertedBalancedRhea 68512

(2Z,6Z)-farnesyl diphosphate = beta-acoradiene + diphosphate

Direction not assertedBalancedRhea 68516

(2E,6E)-farnesyl diphosphate = beta-acoradiene + diphosphate

Direction not assertedBalancedRhea 68520

(2Z,6Z)-farnesyl diphosphate = beta-bisabolene + diphosphate

Direction not assertedBalancedRhea 68524

(2E,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate

Direction not assertedBalancedRhea 68528

(2E,6E)-farnesyl diphosphate = (Z)-alpha-bisabolene + diphosphate

Direction not assertedBalancedRhea 68532

(2E,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 68536

(2Z,6Z)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate

Direction not assertedBalancedRhea 68540

(2Z,6Z)-farnesyl diphosphate = (E)-beta-farnesene + diphosphate

Direction not assertedBalancedRhea 68544

psoralen + reduced [NADPH--hemoprotein reductase] + O2 = xanthotoxol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68548

UDP-N-acetyl-alpha-D-quinovosamine + NADP(+) = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + NADPH + H(+)

Direction not assertedBalancedRhea 68552

UDP-N-acetyl-alpha-D-quinovosamine + NAD(+) = UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + NADH + H(+)

Direction not assertedBalancedRhea 68556

arsenate + D-glyceraldehyde 3-phosphate + NAD(+) = 1-arsono-3-phospho-D-glycerate + NADH + H(+)

Direction not assertedBalancedRhea 68560

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