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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

13,951–14,000 of 18,558 reactions from Rhea

N-(8'-hydroxygeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 = N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 68164
N-(8'-oxogeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 = N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 68168
N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + 2-oxoglutarate + O2 = isodomoate A + succinate + CO2 + H2O
Direction not assertedBalancedRhea 68172
N-geranyl-L-glutamate + 2-oxoglutarate + O2 = dainate A + succinate + CO2 + H2O
Direction not assertedBalancedRhea 68176
a short-chain fatty acyl-CoA + H2O = a short-chain fatty acid + CoA + H(+)
Direction not assertedBalance undeterminableRhea 68180
a medium-chain fatty acyl-CoA + H2O = a medium-chain fatty acid + CoA + H(+)
Direction not asserted

?

Balance undeterminable

Rhea 68184

phytol + dodecanoyl-CoA = dodecanoate phytyl ester + CoA

Direction not assertedBalancedRhea 68188

phytol + decanoyl-CoA = decanoate phytyl ester + CoA

Direction not assertedBalancedRhea 68192

1,2-dihexanoylglycerol + tetradecanoyl-CoA = 1,2-dihexanoyl-3-tetradecanoylglycerol + CoA

Direction not assertedBalancedRhea 68196

1,2-dihexanoylglycerol + hexadecanoyl-CoA = 1,2-dihexanoyl-3-hexadecanoylglycerol + CoA

Direction not assertedBalancedRhea 68200

1,2-dihexanoylglycerol + octadecanoyl-CoA = 1,2-dihexanoyl-3-octadecanoylglycerol + CoA

Direction not assertedBalancedRhea 68204

(7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol = 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68208

1,2-dihexanoylglycerol + (9Z)-octadecenoyl-CoA = 1,2-dihexanoyl-3-(9Z-octadecenoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68212

1,2-dihexanoylglycerol + (9Z,12Z,15Z)-octadecatrienoyl-CoA = 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA

Direction not assertedBalancedRhea 68216

(7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol = (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA

Direction not assertedBalancedRhea 68220

prekainate + 2-oxoglutarate + O2 + H(+) = kainate lactone + succinate + CO2 + H2O

Direction not assertedBalancedRhea 68224

glycine(in) + Na(+)(in) = glycine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68228

L-cysteine(in) + Na(+)(in) = L-cysteine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68232

L-glutamine(in) + Na(+)(in) = L-glutamine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68236

L-methionine(in) + Na(+)(in) = L-methionine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68240

L-phenylalanine(in) + Na(+)(in) = L-phenylalanine(out) + Na(+)(out)

Right to leftBalancedTransportRhea 68244

L-tyrosine(in) + Na(+)(in) = L-tyrosine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 68248

L-tryptophan(in) + Na(+)(in) = L-tryptophan(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 68252

L-cystine(in) + Na(+)(in) = L-cystine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 68256

D-serine(out) + 2 Na(+)(out) = D-serine(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 68260

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formaldehyde

Direction not assertedBalancedRhea 68264

dUMP + formaldehyde + NADPH + H(+) = dTMP + NADP(+) + H2O

Direction not assertedBalancedRhea 68268

L-seryl-[protein] + a fatty acyl-CoA = O-fatty acyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68272

L-seryl-[protein] + butanoyl-CoA = O-butanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68276

pentanoyl-CoA + L-seryl-[protein] = O-pentanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68280

hexanoyl-CoA + L-seryl-[protein] = O-hexanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68284

heptanoyl-CoA + L-seryl-[protein] = O-heptanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68288

nonanoyl-CoA + L-seryl-[protein] = O-nonanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68292

L-seryl-[protein] + dodecanoyl-CoA = O-dodecanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68296

L-seryl-[protein] + tetradecanoyl-CoA = O-tetradecanoyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 68300

3-O-{beta-D-GlcA-(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + 3'-phosphoadenylyl sulfate = 3-O-{O-3-S-beta-D-GlcA-(1->[3)-alpha-D-Xyl-(1->3)-beta-D-GlcA-(1->](n)-4)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 68304

1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate

Direction not assertedBalancedRhea 68308

1D-myo-inositol 1,2,3,4,5-pentakisphosphate + H2O = 1D-myo-inositol 2,3,4,5-tetrakisphosphate + phosphate

Direction not assertedBalancedRhea 68312

1D-myo-inositol 2,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,5-triphosphate + phosphate

Direction not assertedBalancedRhea 68316

1D-myo-inositol 2,4,5-triphosphate + H2O = 1D-myo-inositol 2,5-bisphosphate + phosphate

Direction not assertedBalancedRhea 68320

1D-myo-inositol 2,5-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate

Direction not assertedBalancedRhea 68324

(R)-4'-phosphopantetheine + H2O = (R)-pantetheine + phosphate

Left to rightBalancedRhea 68328

(R)-4'-phosphopantothenate + H2O = (R)-pantothenate + phosphate

Direction not assertedBalancedRhea 68332

(R)-4'-phosphopantetheine sulfonate + H2O = (R)-pantetheine sulfonate + phosphate

Left to rightBalancedRhea 68336

(R)-4'-phospho-S-sulfopantetheine + H2O = (R)-S-sulfopantetheine + phosphate

Left to rightBalancedRhea 68340

GTP + ATP = 3',2'-cGAMP + 2 diphosphate

Direction not assertedBalancedRhea 68344

GTP + ATP = pppA(2'-5')pG + diphosphate

Direction not assertedBalancedRhea 68348

pppA(2'-5')pG = 3',2'-cGAMP + diphosphate

Direction not assertedBalancedRhea 68352

N-acetyl-L-aspartyl-L-glutamate + H2O = N-acetyl-L-aspartate + L-glutamate

Direction not assertedBalancedRhea 68356

L-xylono-1,4-lactone + O2 = dehydro-L-arabinono-1,4-lactone + H2O2 + H(+)

Direction not assertedBalancedRhea 68360

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