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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,351–1,400 of 18,558 reactions from Rhea

2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD(+) + H2O = (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + NADH + 2 H(+)
Direction not assertedBalancedRhea 15681
L-2,4-diaminobutanoate + H(+) = propane-1,3-diamine + CO2
Direction not assertedBalancedRhea 15689
(R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + AH2 = (R)-2-hydroxy-(9Z,12Z,15Z)-octadecatrienoate + A + H2O
Direction not assertedBalancedRhea 15693
(2S)-liquiritigenin + reduced [NADPH--hemoprotein reductase] + O2 = licodione + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Direction not assertedBalance undeterminableRhea 15697
phenylacetyl-CoA + 2 a ubiquinone + H2O = phenylglyoxylyl-CoA + 2 a ubiquinol
Direction not assertedBalance undeterminableRhea 15705
kaempferol + UDP-alpha-D-galactose = kaempferol 3-O-beta-D-galactoside + UDP + H(+)
Direction not assertedBalanced

Rhea 15709

a beta-D-galactoside + acetyl-CoA = a 6-acetyl-beta-D-galactoside + CoA

Direction not assertedBalance undeterminableRhea 15713

daunorubicin + NADPH + O2 + H(+) = doxorubicin + NADP(+) + H2O

Direction not assertedBalancedRhea 15717

glycine + NAD(+) + H2O = glyoxylate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 15721

1,5-anhydro-D-fructose = ascopyrone M + H2O

Direction not assertedBalancedRhea 15725

D-mannonate + NAD(+) = keto-D-fructuronate + NADH + H(+)

Direction not assertedBalancedRhea 15729

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2

Direction not assertedBalancedRhea 15733

cyclopentanone + NADPH + O2 + H(+) = 5-valerolactone + NADP(+) + H2O

Direction not assertedBalancedRhea 15737

2,5-dichlorocyclohexa-2,5-dien-1,4-diol + NAD(+) = 2,5-dichlorohydroquinone + NADH + H(+)

Direction not assertedBalancedRhea 15741

[(2->1)-beta-D-fructosyl](n) + sucrose = [(2->1)-beta-D-fructosyl](n+1) + D-glucose

Direction not assertedBalance undeterminableRhea 15745

(S)-mandelate + A = phenylglyoxylate + AH2

Direction not assertedBalancedRhea 15749

IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)

Direction not assertedBalancedRhea 15753

L-homoserine + NAD(+) = L-aspartate 4-semialdehyde + NADH + H(+)

Direction not assertedBalancedRhea 15757

L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)

Direction not assertedBalancedRhea 15761

adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)

Direction not assertedBalancedRhea 15765

adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15769

dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15773

1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate

Direction not assertedBalancedRhea 15777

L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate

Direction not assertedBalancedRhea 15781

L-xylose + NADP(+) = L-xylono-1,4-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 15789

(4Z,15Z)-bilirubin IXalpha + NADP(+) = biliverdin IXalpha + NADPH + H(+)

Right to leftBalancedRhea 15793

(4Z,15Z)-bilirubin IXalpha + NAD(+) = biliverdin IXalpha + NADH + H(+)

Right to leftBalancedRhea 15797

a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 15801

(7R,8S)-7,8-diammoniononanoate + CO2 + ATP = (4R,5S)-dethiobiotin + ADP + phosphate + 3 H(+)

Direction not assertedBalancedRhea 15805

(2E)-geranyl diphosphate + H2O = (R)-linalool + diphosphate

Direction not assertedBalancedRhea 15809

1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA

Direction not assertedBalancedRhea 15813

pyridoxamine 5'-phosphate + O2 + H2O = pyridoxal 5'-phosphate + H2O2 + NH4(+)

Left to rightBalancedRhea 15817

glycine + 2 A = hydrogen cyanide + 2 AH2 + CO2

Direction not assertedBalancedRhea 15821

AZD1979 + H2O = AZD1979 oxetane hydrolysis product + H(+)

Direction not assertedBalancedRhea 15825

a 16alpha-hydroxysteroid = a 16beta-hydroxysteroid

Direction not assertedBalance undeterminableRhea 15829

(S)-4-hydroxymandelate + O2 + H(+) = 4-hydroxybenzaldehyde + H2O2 + CO2

Direction not assertedBalancedRhea 15833

methylamine + L-glutamate = N-methyl-L-glutamate + NH4(+)

Direction not assertedBalancedRhea 15837

D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)

Left to rightBalancedRhea 15841

4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose = 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP + n H(+)

Direction not assertedBalance undeterminableRhea 15845

L-ascorbate + 2 Fe(III)-[cytochrome c] = L-dehydroascorbate + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 15849

(17R,20S)-17,20-dihydroxypregn-4-en-3-one + NAD(+) = 17alpha-hydroxyprogesterone + NADH + H(+)

Direction not assertedBalancedRhea 15853

(17R,20S)-17,20-dihydroxypregn-4-en-3-one + NADP(+) = 17alpha-hydroxyprogesterone + NADPH + H(+)

Right to leftBalancedRhea 15857

3-ADP-2-phosphoglycerate + H2O = 3-ADP-glycerate + phosphate

Direction not assertedBalancedRhea 15861

tryptamine + AH2 + O2 = 4-hydroxytryptamine + A + H2O

Direction not assertedBalancedRhea 15865

D-alanine + 2-oxoglutarate = D-glutamate + pyruvate

Direction not assertedBalancedRhea 15869

an NDP-alpha-D-glucose + [(1->4)-alpha-D-glucosyl](n) = [(1->4)-alpha-D-glucosyl](n+1) + a ribonucleoside 5'-diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 15873

pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate

Direction not assertedBalancedRhea 15877

L-seryl-[Fas-activated protein] + ATP = O-phospho-L-seryl-[Fas-activated protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 15881

propane-1,2-diol + NADP(+) = (S)-lactaldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 15885

L-glutamine + H2O = L-glutamate + NH4(+)

Direction not assertedBalancedRhea 15889

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