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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Reach

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Organisms
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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

13,601–13,650 of 18,558 reactions from Rhea

domoate(in) + ATP + H2O = domoate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66756
kainate(in) + ATP + H2O = kainate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66760
folate(in) + ATP + H2O = folate(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66764
coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66768
uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66772
uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 66776
6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine + H2O = N-acetyl-D-muramate 6-phosphate + N-acetyl-D-glucosamine

Direction not assertedBalancedRhea 66780

N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 66784

N-methyl-L-dopa + O2 = (3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2

Direction not assertedBalancedRhea 66788

N-methyl-D-dopa + O2 = (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2

Direction not assertedBalancedRhea 66792

miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 11-oxomiltiradiene + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 66796

miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = miltiradien-20-al + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 66800

ferruginol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = pisiferate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66804

5-aminopentanoate + 7 malonyl-CoA + acetyl-CoA + 11 NADPH + 17 H(+) = wortmanamide A + 7 CO2 + 11 NADP(+) + 8 CoA + 6 H2O

Direction not assertedBalancedRhea 66808

5-aminopentanoate + 8 malonyl-CoA + acetyl-CoA + 13 NADPH + 20 H(+) = wortmanamide B + 8 CO2 + 13 NADP(+) + 9 CoA + 7 H2O

Direction not assertedBalancedRhea 66812

tetrahydroxoborate(in) + 2 Na(+)(in) = tetrahydroxoborate(out) + 2 Na(+)(out)

Left to rightBalancedTransportRhea 66816

Mn(2+)(in) + ATP + H2O = Mn(2+)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66820

2 cob(II)inamide + reduced [electron-transfer flavoprotein] + 2 ATP + 2 H2O = 2 adenosylcob(III)inamide + oxidized [electron-transfer flavoprotein] + 2 phosphate + 2 diphosphate + 3 H(+)

Direction not assertedBalance undeterminableRhea 66824

2 cob(II)alamin + reduced [electron-transfer flavoprotein] + 2 ATP + 2 H2O = 2 adenosylcob(III)alamin + oxidized [electron-transfer flavoprotein] + 2 phosphate + 2 diphosphate + 3 H(+)

Direction not assertedBalance undeterminableRhea 66828

(2E,6E,10E,14E)-geranylfarnesyl diphosphate = preasperterpenoid A + diphosphate

Direction not assertedBalancedRhea 66832

preasperterpenoid A + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = asperterpenoid A + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)

Direction not assertedBalance undeterminableRhea 66836

asperterpenoid A + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = asperterpenoid B + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)

Direction not assertedBalance undeterminableRhea 66840

asperterpenoid A + reduced [NADPH--hemoprotein reductase] + O2 = asperterpenoid C + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 66844

2 Cu(2+) + NADH = 2 Cu(+) + NAD(+) + H(+)

Direction not assertedBalancedRhea 66848

2 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate

Direction not assertedBalancedRhea 66852

3 isopentenyl diphosphate + (2E)-geranyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate

Direction not assertedBalancedRhea 66856

4 isopentenyl diphosphate + dimethylallyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate

Direction not assertedBalancedRhea 66860

(2E,6E,10E,14E)-geranylfarnesyl diphosphate = quiannulatene + diphosphate

Direction not assertedBalancedRhea 66864

quiannulatene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = quiannulatate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66868

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66872

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 12-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66876

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66880

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66884

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 8-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66888

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66892

ophiobolin F + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase] + 6 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66896

L-tryptophan + malonyl-CoA + acetyl-CoA = cyclo-acetoacetyl-L-tryptophan + CO2 + 2 CoA + H2O

Direction not assertedBalancedRhea 66900

cannabinerolate + A = cannabichromenate + AH2

Direction not assertedBalancedRhea 66904

9 malonyl-CoA + acetyl-CoA + S-adenosyl-L-methionine + 13 NADPH + 20 H(+) = soppiline A + S-adenosyl-L-homocysteine + 9 CO2 + 13 NADP(+) + 10 CoA + 7 H2O

Direction not assertedBalancedRhea 66908

avenanthramide C + S-adenosyl-L-methionine = avenanthramide B + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 66912

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 66916

6-deoxy-6-sulfo-D-fructose + D-erythrose 4-phosphate = (2S)-3-sulfolactaldehyde + D-sedoheptulose 7-phosphate

Direction not assertedBalancedRhea 66920

[(R)-3-hydroxyalkanoate](n) + a (3R)-3-hydroxyacyl-CoA = [(R)-3-hydroxyalkanoate](n+1) + CoA

Direction not assertedBalance undeterminableRhea 66924

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)

Left to rightBalance undeterminableRhea 66928

5-hydroxyanthranilate + (E)-4-coumaroyl-CoA = avenanthramide A + CoA

Direction not assertedBalancedRhea 66932

5-hydroxyanthranilate + (E)-caffeoyl-CoA = avenanthramide C + CoA

Direction not assertedBalancedRhea 66936

11 malonyl-CoA + acetyl-CoA + S-adenosyl-L-methionine + 12 NADPH + 22 H(+) = soppiline B + S-adenosyl-L-homocysteine + 12 CO2 + 12 NADP(+) + 12 CoA + 8 H2O

Direction not assertedBalancedRhea 66940

soppiline B + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = soppiline C + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 66944

alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + acetyl-CoA = alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CoA

Direction not assertedBalancedRhea 66948

alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose = alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + dTDP + H(+)

Direction not assertedBalancedRhea 66952

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