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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
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Interactions
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Reactions
Reach

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Cell types
Organisms
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

13,451–13,500 of 18,558 reactions from Rhea

2-phenylethylamine + acetyl-CoA = N-(2-phenylethyl)acetamide + CoA + H(+)
Direction not assertedBalancedRhea 66148
noradrenaline + acetyl-CoA = N-acetylnoradrenaline + CoA + H(+)
Direction not assertedBalancedRhea 66152
tyramine + butanoyl-CoA = N-butanoyltyramine + CoA + H(+)
Direction not assertedBalancedRhea 66156
tyramine + hexanoyl-CoA = N-hexanoyltyramine + CoA + H(+)
Direction not assertedBalancedRhea 66160
serotonin + butanoyl-CoA = N-butanoylserotonin + CoA + H(+)
Direction not assertedBalancedRhea 66164
[protein]-with a C-terminal TM segment(out) + ATP + H2O = [protein]-with a C-terminal TM segment(in) + ADP + phosphate + H(+)
Direction not assertedBalance undeterminableTransportRhea 66168
L-cystine(out) + H(+)(out) = L-cystine(in) + H(+)(in)

Left to rightBalancedTransportRhea 66172

taurochenodeoxycholate 3-sulfate(in) + ATP + H2O = taurochenodeoxycholate 3-sulfate(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66176

(4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66180

3',5'-cyclic AMP(in) + ATP + H2O = 3',5'-cyclic AMP(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66184

3',5'-cyclic GMP(in) + ATP + H2O = 3',5'-cyclic GMP(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66188

(4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66192

tryptamine + acetyl-CoA = N-acetyltryptamine + CoA + H(+)

Direction not assertedBalancedRhea 66196

pentanoyl-CoA + O2 = (2E)-pentenoyl-CoA + H2O2

Direction not assertedBalancedRhea 66200

heptanoyl-CoA + O2 = (2E)-heptenoyl-CoA + H2O2

Direction not assertedBalancedRhea 66204

(8R)-8-hydroxynonanoyl-CoA + O2 = (2E,8R)-8-hydroxynonenoyl-CoA + H2O2

Direction not assertedBalancedRhea 66208

asc-omegaC5-CoA + O2 = asc-omegaDeltaC5-CoA + H2O2

Direction not assertedBalancedRhea 66212

asc-C7-CoA + O2 = asc-DeltaC7-CoA + H2O2

Direction not assertedBalancedRhea 66216

asc-omegaC7-CoA + O2 = asc-omegaDeltaC7-CoA + H2O2

Direction not assertedBalancedRhea 66220

asc-C9-CoA + O2 = asc-DeltaC9-CoA + H2O2

Direction not assertedBalancedRhea 66224

asc-C13-CoA + O2 = asc-DeltaC13-CoA + H2O2

Direction not assertedBalancedRhea 66228

IC-asc-C7-CoA + O2 = IC-asc-DeltaC7-CoA + H2O2

Direction not assertedBalancedRhea 66232

IC-asc-C9-CoA + O2 = IC-asc-DeltaC9-CoA + H2O2

Direction not assertedBalancedRhea 66236

IC-asc-C9 + ATP + CoA = IC-asc-C9-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 66240

IC-asc-C9 + ATP + H(+) = IC-asc-C9-AMP + diphosphate

Direction not assertedBalancedRhea 66244

IC-asc-C9-AMP + CoA = IC-asc-C9-CoA + AMP + H(+)

Direction not assertedBalancedRhea 66248

IC-asc-C7 + ATP + CoA = IC-asc-C7-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 66252

IC-asc-C7 + ATP + H(+) = IC-asc-C7-AMP + diphosphate

Direction not assertedBalancedRhea 66256

IC-asc-C7-AMP + CoA = IC-asc-C7-CoA + AMP + H(+)

Direction not assertedBalancedRhea 66260

nonanoate + ATP + H(+) = nonanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 66264

nonanoyl-AMP + CoA = nonanoyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 66268

a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 66272

tigogenin + UDP-alpha-D-glucose = tigogenin 3-O-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 66276

solanidine + UDP-alpha-D-glucose = solanidine 3-O-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 66280

tomatidine + UDP-alpha-D-glucose = tomatidine 3-O-beta-D-glucopyranoside + UDP + H(+)

Direction not assertedBalancedRhea 66284

an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 66288

an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)

Direction not assertedBalance undeterminableRhea 66292

an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 66300

an alpha-mannosylinositol-1-phosphoceramide + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol-1-phospho-alpha-mannosylinositol-1-phosphoceramide + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 66304

an inositol-1-phosphoceramide + GDP-alpha-D-mannose = an alpha-mannosylinositol-1-phosphoceramide + GDP + H(+)

Direction not assertedBalance undeterminableRhea 66308

an alpha-mannosylinositol-1-phosphoceramide + H2O = a D-mannosyl-alpha-1->6-inositol-1-phosphate + an N-acyl-sphingoid base + H(+)

Direction not assertedBalance undeterminableRhea 66312

an inositol phosphomannosyl-alpha-1->6-inositol-1-phospho-N-acyl-4R-hydroxysphinganine + H2O = alpha-D-mannosyl-di-(inositol-1-phosphate) + an N-acyl-(4R)-4-hydroxysphinganine + H(+)

Direction not assertedBalance undeterminableRhea 66316

2',3'-cGAMP(out) = 2',3'-cGAMP(in)

ReversibleBalancedTransportRhea 66320

iodide(out) = iodide(in)

ReversibleBalancedTransportRhea 66324

taurine(out) = taurine(in)

ReversibleBalancedTransportRhea 66328

L-aspartate(out) = L-aspartate(in)

Left to rightBalancedTransportRhea 66332

L-glutamate(out) = L-glutamate(in)

ReversibleBalancedTransportRhea 66336

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 66340

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 66344

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + A = (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + AH2

Direction not assertedBalancedRhea 66348

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