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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,301–1,350 of 18,558 reactions from Rhea

1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide
Direction not assertedBalancedRhea 15469
flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose = flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + UDP + H(+)
Direction not assertedBalancedRhea 15473
5beta-scymnol + 3'-phosphoadenylyl sulfate = 5beta-scymnol sulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 15477
(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
ReversibleBalancedRhea 15481
(2R,3S)-homoisocitrate = cis-homoaconitate + H2O
Direction not assertedBalancedRhea 15485
adenosine + 2 O2 + H2O = 9-riburonosyladenine + 2 H2O2 + H(+)
Direction not assertedBalanced

Rhea 15489

1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine

Direction not assertedBalancedRhea 15497

2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH + H(+)

Direction not assertedBalancedRhea 15501

(S)-2-hydroxymethylglutarate + NAD(+) = 2-formylglutarate + NADH + H(+)

Direction not assertedBalancedRhea 15505

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 15509

keto-D-tagatose + ATP = keto-D-tagatose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15513

N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + sulfate + H(+)

Direction not assertedBalancedRhea 15517

N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 15521

bis(2-ethylhexyl)phthalate + H2O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+)

Direction not assertedBalancedRhea 15529

(2R)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + NADH + H(+)

Direction not assertedBalancedRhea 15533

(2R)-3-sulfolactate + NADP(+) = 3-sulfopyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 15537

DIMBOA + UDP-alpha-D-glucose = DIMBOA beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 15541

(3S)-citramalate = acetate + pyruvate

Direction not assertedBalancedRhea 15545

5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O

Direction not assertedBalancedRhea 15549

1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate

Left to rightBalancedRhea 15553

Ni(2+)(out) + ATP + H2O = Ni(2+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 15557

sterigmatocystin + S-adenosyl-L-methionine = 8-O-methylsterigmatocystin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15561

an N-acyl-L-amino acid + H2O = an L-alpha-amino acid + a carboxylate

ReversibleBalance undeterminableRhea 15565

N-acetylserotonin + S-adenosyl-L-methionine = melatonin + S-adenosyl-L-homocysteine + H(+)

Right to leftBalancedRhea 15573

uridine + H2O = D-ribose + uracil

Direction not assertedBalancedRhea 15577

biochanin A 7-O-beta-D-glucoside + malonyl-CoA = biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA

Direction not assertedBalancedRhea 15581

15-cis-phytoene + 4 A = all-trans-lycopene + 4 AH2

Direction not assertedBalancedRhea 15585

D-4-hydroxyphenylglycine + 2-oxoglutarate = 4-hydroxyphenylglyoxylate + L-glutamate

Direction not assertedBalancedRhea 15589

amicoumacin A 2-phosphate + H2O = amicoumacin A + phosphate

Direction not assertedBalancedRhea 15593

a Fe(III)-siderophore(out) + ATP + H2O = a Fe(III)-siderophore(in) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 15597

(E)-cinnamoyl-CoA + (R)-3-phenyllactate = (R)-3-phenyllactoyl-CoA + (E)-cinnamate

Direction not assertedBalancedRhea 15601

L-serine O-sulfate + H2O = sulfate + pyruvate + NH4(+) + H(+)

Direction not assertedBalancedRhea 15605

D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)

Left to rightBalancedRhea 15609

precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)

Direction not assertedBalancedRhea 15613

Fe(3+) + Fe(II)-[cytochrome c] = Fe(2+) + Fe(III)-[cytochrome c]

Direction not assertedBalance undeterminableRhea 15617

an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 15621

Co-precorrin-6B + NAD(+) = Co-precorrin-6A + NADH + H(+)

Direction not assertedBalancedRhea 15625

a steroid + 2 reduced [adrenodoxin] + O2 + 2 H(+) = an 11beta-hydroxysteroid + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 15629

3,4-dihydroxyphenylacetate + O2 = 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)

Direction not assertedBalancedRhea 15633

[alginate](n) + GDP-alpha-D-mannuronate = [alginate](n+1) + GDP + H(+)

Direction not assertedBalance undeterminableRhea 15637

oxaloacetate + H(+) = pyruvate + CO2

Left to rightBalancedRhea 15641

N2 + 4 reduced [flavodoxin] + 16 ATP + 16 H2O = 4 oxidized [flavodoxin] + H2 + 2 NH4(+) + 16 ADP + 16 phosphate + 18 H(+)

Direction not assertedBalance undeterminableRhea 15645

carbamate + 2 H(+) = NH4(+) + CO2

Direction not assertedBalancedRhea 15649

beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 15653

1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO2 + NADH

Direction not assertedBalancedRhea 15657

an anthocyanidin 3,5-di-O-beta-D-glucoside + (E)-4-coumaroyl-CoA = an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA

Direction not assertedBalance undeterminableRhea 15661

aldehydo-D-glucose + L-lysyl-[protein] = N(6)-(D-fructosyl)-L-lysyl-[protein] + H2O

Direction not assertedBalance undeterminableRhea 15665

a 5'-end dephospho-2'-deoxyribonucleoside-DNA + ATP = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + ADP + H(+)

Direction not assertedBalance undeterminableRhea 15669

acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+)

Left to rightBalancedRhea 15673

5-aminopentanamide + H2O = 5-aminopentanoate + NH4(+)

Direction not assertedBalancedRhea 15677

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