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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

13,251–13,300 of 18,558 reactions from Rhea

7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA = 3-oxochol-4,6-dien-24-oyl-CoA + H2O
Direction not assertedBalancedRhea 65348
7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O
Direction not assertedBalancedRhea 65352
1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)
Left to rightBalancedRhea 65356
a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O = a 5'-end phospho (purine-ribonucleoside) in mRNA + N(2),N(2),N(7)-trimethyl-GDP + 2 H(+)
Direction not assertedBalance undeterminableRhea 65360
a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O = a 5'-end phospho-guanosine in mRNA + N(2),N(2),N(7)-trimethyl-GDP + 2 H(+)
Direction not assertedBalance undeterminableRhea 65364
a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O = a 5'-end phospho-adenosine in mRNA + N(2),N(2),N(7)-trimethyl-GDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 65368

a globoside GalGb4Cer + CMP-N-acetyl-beta-neuraminate = a globoside MSGG + CMP + H(+)

Left to rightBalance undeterminableRhea 65372

a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 65376

a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 65380

a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+)

Direction not assertedBalance undeterminableRhea 65384

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + N(7)-methyl-GMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 65388

L-pipecolate + malonyl-CoA + 2 NADPH + 4 H(+) = (8aS)-octahydroindolizin-1-one + CO2 + 2 NADP(+) + CoA + 2 H2O

Direction not assertedBalancedRhea 65392

8-oxo-dATP + H2O = 8-oxo-dAMP + diphosphate + H(+)

Left to rightBalancedRhea 65396

butan-1-ol + butanoyl-CoA = butyl butanoate + CoA

Direction not assertedBalancedRhea 65400

butan-1-ol + hexanoyl-CoA = butyl hexanoate + CoA

Direction not assertedBalancedRhea 65404

NAD(+)(in) = NAD(+)(out)

Direction not assertedBalancedTransportRhea 65408

dAMP(in) + NAD(+)(out) = dAMP(out) + NAD(+)(in)

Direction not assertedBalancedTransportRhea 65412

dGMP(in) + NAD(+)(out) = dGMP(out) + NAD(+)(in)

Direction not assertedBalancedTransportRhea 65416

GMP(in) + NAD(+)(out) = GMP(out) + NAD(+)(in)

Direction not assertedBalancedTransportRhea 65420

AMP(in) + NAD(+)(out) = AMP(out) + NAD(+)(in)

Direction not assertedBalancedTransportRhea 65424

deamido-NAD(+)(in) + NAD(+)(out) = deamido-NAD(+)(out) + NAD(+)(in)

Direction not assertedBalancedTransportRhea 65428

a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+)

Left to rightBalance undeterminableRhea 65432

a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate

Direction not assertedBalance undeterminableRhea 65436

a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 65440

hexan-1-ol + butanoyl-CoA = hexyl butanoate + CoA

Direction not assertedBalancedRhea 65444

ethanol + butanoyl-CoA = ethyl butanoate + CoA

Direction not assertedBalancedRhea 65448

hexanoyl-CoA + ethanol = ethyl hexanoate + CoA

Direction not assertedBalancedRhea 65452

2-methylbutan-1-ol + acetyl-CoA = 2-methylbutyl acetate + CoA

Direction not assertedBalancedRhea 65456

hexan-1-ol + acetyl-CoA = hexyl acetate + CoA

Direction not assertedBalancedRhea 65460

2-methylbutan-1-ol + butanoyl-CoA = 2-methylbutyl butanoate + CoA

Direction not assertedBalancedRhea 65464

1-propanol + acetyl-CoA = propyl acetate + CoA

Direction not assertedBalancedRhea 65468

2-methylbutanoyl-CoA + ethanol = ethyl 2-methylbutanoate + CoA

Direction not assertedBalancedRhea 65472

1-propanol + butanoyl-CoA = propyl butanoate + CoA

Direction not assertedBalancedRhea 65476

2-methylbutanoyl-CoA + hexan-1-ol = hexyl 2-methylbutanoate + CoA

Direction not assertedBalancedRhea 65480

hexan-1-ol + hexanoyl-CoA = hexyl hexanoate + CoA

Direction not assertedBalancedRhea 65484

3 ATP = 2',3',3'-c-tri-AMP + 3 diphosphate

Direction not assertedBalancedRhea 65488

[mycofactocin precursor peptide]-C-terminal glycyl-L-valyl-L-tyrosine + S-adenosyl-L-methionine = [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + 5'-deoxyadenosine + L-methionine + CO2

Direction not assertedBalance undeterminableRhea 65492

3beta-hydroxy-5beta-pregnane-20-one + NADPH + H(+) = 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+)

Left to rightBalancedRhea 65496

[mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine = [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + 5'-deoxyadenosine + L-methionine + A + H(+)

Direction not assertedBalance undeterminableRhea 65500

[mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + H2O = [mycofactocin precursor peptide]-C-terminal glycine + 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one

Direction not assertedBalance undeterminableRhea 65504

3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 + H2O = pre-mycofactocin + H2O2 + NH4(+)

Direction not assertedBalancedRhea 65508

3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 = 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O2 + H(+)

Direction not assertedBalancedRhea 65512

5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H2O + H(+) = pre-mycofactocin + NH4(+)

Direction not assertedBalancedRhea 65516

all-trans-retinol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = all-trans-3-hydroxyretinol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 65520

9-cis-retinal + reduced [NADPH--hemoprotein reductase] + O2 = 9-cis-retinoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 65524

hexan-1-ol + octanoyl-CoA = hexyl octanoate + CoA

Direction not assertedBalancedRhea 65528

2-methylbutan-1-ol + hexanoyl-CoA = 2-methylbutyl hexanoate + CoA

Direction not assertedBalancedRhea 65532

1,3,7-trimethylurate + S-adenosyl-L-methionine = theacrine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 65536

a ganglioside GM3 + H2O = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose + an N-acyl-sphingoid base

Direction not assertedBalance undeterminableRhea 65540

a ganglioside GM1 + H2O = beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc + an N-acyl-sphingoid base

Direction not assertedBalance undeterminableRhea 65544

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