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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

13,201–13,250 of 18,558 reactions from Rhea

phloretin + UDP-alpha-D-glucose = trilobatin + UDP + H(+)
Direction not assertedBalancedRhea 65148
(2S)-naringenin + UDP-alpha-D-glucose = (2S)-naringenin 7-O-beta-D-glucoside + UDP + H(+)
Direction not assertedBalancedRhea 65152
preaustinoid A2 + 2-oxoglutarate + O2 = preaustinoid A3 + succinate + CO2 + H2O
Direction not assertedBalancedRhea 65156
hexan-2-ol + benzoyl-CoA = hexan-2-yl benzoate + CoA
Direction not assertedBalancedRhea 65160
hexan-3-ol + benzoyl-CoA = hexan-3-yl benzoate + CoA
Direction not assertedBalancedRhea 65164
preaustinoid A + AH2 + O2 = preaustinoid A1 + A + H2O
Direction not assertedBalancedRhea 65168
(3Z,5E)-dodecadienoyl-CoA + H2O = (3Z,5E)-dodecadienoate + CoA + H(+)

Direction not assertedBalancedRhea 65172

protoaustinoid A + A = protoaustinoid B + AH2

Direction not assertedBalancedRhea 65176

protoaustinoid B + AH2 + O2 = preaustinoid A + A + H2O

Direction not assertedBalancedRhea 65180

preaustinoid A1 + 2-oxoglutarate + O2 = berkeleyone B + succinate + CO2 + H2O

Direction not assertedBalancedRhea 65184

berkeleyone B + 2-oxoglutarate + O2 = berkeleydione + succinate + CO2 + H2O

Direction not assertedBalancedRhea 65188

preaustinoid A + 2 2-oxoglutarate + 2 O2 = berkeleytrione + 2 succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 65192

S-(2-aminoethyl)-L-cysteine + NAD(+) + H2O = S-(acetaldehyde)-L-cysteine + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 65196

S-(acetaldehyde)-L-cysteine = (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + H2O + H(+)

Direction not assertedBalancedRhea 65200

(3R)-3-hydroxybutanoyl-CoA + H2O = (R)-3-hydroxybutanoate + CoA + H(+)

Direction not assertedBalancedRhea 65204

(3S)-3-hydroxybutanoyl-CoA + H2O = (S)-3-hydroxybutanoate + CoA + H(+)

Direction not assertedBalancedRhea 65208

(2E)-dodecenoyl-CoA + H2O = (2E)-dodecenoate + CoA + H(+)

Direction not assertedBalancedRhea 65212

3-oxododecanoyl-CoA + H2O = 3-oxododecanoate + CoA + H(+)

Direction not assertedBalancedRhea 65216

(1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH + H(+)

Direction not assertedBalancedRhea 65220

(1R,2R)-1,2-dihydronaphthalene-1,2-diol + NADP(+) = naphthalene-1,2-diol + NADPH + H(+)

Direction not assertedBalancedRhea 65224

(1S,2S)-1,2-dihydronaphthalene-1,2-diol + NADP(+) = naphthalene-1,2-diol + NADPH + H(+)

Direction not assertedBalancedRhea 65228

3-hydroxydodecanoyl-CoA + H2O = 3-hydroxydodecanoate + CoA + H(+)

Direction not assertedBalancedRhea 65232

3-methylbutan-1-ol + acetyl-CoA = 3-methylbutyl acetate + CoA

Direction not assertedBalancedRhea 65236

(11Z)-octadecenoyl-CoA + H2O = (11Z)-octadecenoate + CoA + H(+)

Direction not assertedBalancedRhea 65240

(2S)-hesperetin + UDP-alpha-D-glucose = (2S)-hesperetin 7-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 65244

5 malonyl-CoA + AH2 + 5 H(+) = 6-hydroxymellein + A + 5 CO2 + 5 CoA + H2O

Direction not assertedBalancedRhea 65248

6-hydroxymellein + (2E,6E)-farnesyl diphosphate = verruculide C + diphosphate

Direction not assertedBalancedRhea 65252

verruculide C + AH2 + O2 = verruculide C epoxide + A + H2O

Direction not assertedBalancedRhea 65256

verruculide C epoxide = 3-hydroxypentacecilide A

Direction not assertedBalancedRhea 65260

3-hydroxypentacecilide A + A = chrodrimanin C + AH2

Direction not assertedBalancedRhea 65264

3-hydroxypentacecilide A + NADPH + O2 + H(+) = chrodrimanin F + NADP(+) + H2O

Direction not assertedBalancedRhea 65268

chrodrimanin C + NADPH + O2 + H(+) = chrodrimanin H + NADP(+) + H2O

Direction not assertedBalancedRhea 65272

testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 65276

3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Ser-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-seryl-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 65280

3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Thr-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 65284

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine + CMP + H(+)

Left to rightBalancedRhea 65288

butan-2-one + hydrogencarbonate + 2 ATP + 3 H2O = 3-oxopentanoate + 2 AMP + 4 phosphate + 4 H(+)

Direction not assertedBalancedRhea 65292

(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 65296

chrodrimanin C + 2-oxoglutarate + O2 = verruculide A + succinate + CO2 + H2O

Direction not assertedBalancedRhea 65300

verruculide A + 2-oxoglutarate + O2 = chrodrimanin T + succinate + CO2

Direction not assertedBalancedRhea 65304

an ultra-long-chain di-unsaturated fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxo-ultra-long-chain di-unsaturated fatty acyl-[ACP] + holo-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 65308

an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + holo-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 65312

chrodrimanin H + 2-oxoglutarate + O2 = chrodrimanin E + succinate + CO2 + H2O

Direction not assertedBalancedRhea 65316

chrodrimanin E + 2-oxoglutarate + O2 = chrodrimanin A + succinate + CO2

Direction not assertedBalancedRhea 65320

chrodrimanin A + acetyl-CoA = chrodrimanin B + CoA

Direction not assertedBalancedRhea 65324

chrodrimanin F + A = chrodrimanin H + AH2

Direction not assertedBalancedRhea 65328

verruculide A + NADPH + O2 + H(+) = chrodrimanin E + NADP(+) + H2O

Direction not assertedBalancedRhea 65332

chrodrimanin T + NADPH + O2 + H(+) = chrodrimanin A + NADP(+) + H2O

Direction not assertedBalancedRhea 65336

L-threonyl-[protein] + acetyl-CoA = O-acetyl-L-threonyl-[protein] + CoA

Direction not assertedBalance undeterminableRhea 65340

valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 65344

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