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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

12,951–13,000 of 18,558 reactions from Rhea

N-(9Z-octadecenoyl)-L-methionine + H2O = (9Z)-octadecenoate + L-methionine
Left to rightBalancedRhea 64144
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc derivative + CMP + H(+)
Direction not assertedBalance undeterminableRhea 64148
alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP-N-acetyl-beta-neuraminate = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP + H(+)
Direction not assertedBalancedRhea 64152
an N-(fatty acyl)-L-methionine + H2O = a fatty acid + L-methionine
Direction not assertedBalance undeterminableRhea 64156
glycyl-[methyl-coenzyme M reductase] + hydrogen sulfide + ATP = thioglycyl-[methyl-coenzyme M reductase] + ADP + phosphate
Direction not assertedBalance undeterminableRhea 64160
2-methyl-L-serine = formaldehyde + L-alanine

? Direction not asserted

Balanced

Rhea 64164

2-ethyl-L-serine = (2S)-2-aminobutanoate + formaldehyde

Direction not assertedBalancedRhea 64168

L-altrarate = galactarate

Direction not assertedBalancedRhea 64172

N-(9Z-octadecenoyl)-L-tryptophan + H2O = L-tryptophan + (9Z)-octadecenoate

Left to rightBalancedRhea 64176

an N-(fatty acyl)-L-tryptophan + H2O = L-tryptophan + a fatty acid

Direction not assertedBalance undeterminableRhea 64180

N-(9Z-octadecenoyl)-L-tyrosine + H2O = L-tyrosine + (9Z)-octadecenoate

Left to rightBalancedRhea 64184

an N-(fatty acyl)-L-tyrosine + H2O = L-tyrosine + a fatty acid

Direction not assertedBalance undeterminableRhea 64188

N-(9Z-octadecenoyl)-L-lysine + H2O = L-lysine + (9Z)-octadecenoate

Left to rightBalancedRhea 64192

an N-(fatty acyl)-L-lysine + H2O = L-lysine + a fatty acid

Direction not assertedBalance undeterminableRhea 64196

an N-(fatty acyl)-L-leucine + H2O = L-leucine + a fatty acid

Direction not assertedBalance undeterminableRhea 64200

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA

Left to rightBalancedRhea 64204

an N-(fatty acyl)-L-glutamine + H2O = L-glutamine + a fatty acid

Direction not assertedBalance undeterminableRhea 64208

an N-(fatty acyl)-L-isoleucine + H2O = L-isoleucine + a fatty acid

Direction not assertedBalance undeterminableRhea 64212

2-carboxy-L-lyxonate + H(+) = L-lyxonate + CO2

Direction not assertedBalancedRhea 64216

N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + H2O = taurine + (5Z,8Z,11Z,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 64220

uridine(34) in tRNA + AH2 + O2 = 5-hydroxyuridine(34) in tRNA + A + H2O

Direction not assertedBalancedRhea 64224

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(10Z-heptadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA

Left to rightBalancedRhea 64228

holo-[ACP] + 8 malonyl-CoA + 8 H(+) = (3R)-atrochrysone 2-carbonyl-[ACP] + 8 CO2 + 8 CoA + 2 H2O

Direction not assertedBalance undeterminableRhea 64232

(3R)-atrochrysone 2-carbonyl-[ACP] + H2O = (3R)-atrochrysone 2-carboxylate + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 64236

octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)

Direction not assertedBalancedRhea 64240

a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 64244

decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)

Direction not assertedBalancedRhea 64248

tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)

Direction not assertedBalancedRhea 64252

dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)

Direction not assertedBalancedRhea 64256

(9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)

Direction not assertedBalancedRhea 64260

(3R)-atrochrysone 2-carboxylate + H(+) = (3R)-atrochrysone + CO2

Direction not assertedBalancedRhea 64264

emodin anthrone + O2 = emodin + H2O + H(+)

Direction not assertedBalancedRhea 64268

benzylamine + pyruvate = benzaldehyde + L-alanine

Direction not assertedBalancedRhea 64272

chrysophanol-9-anthrone + O2 = chrysophanol + H2O

Direction not assertedBalancedRhea 64276

(S)-1-phenylethylamine + pyruvate = acetophenone + L-alanine

Direction not assertedBalancedRhea 64280

2-phenylethylamine + pyruvate = 2-phenylacetaldehyde + L-alanine

Direction not assertedBalancedRhea 64284

2 nataloe emodin + reduced [NADPH--hemoprotein reductase] + O2 = cladofulvin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 64288

3,8,9,10-tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one + NADPH + H(+) = (3R)-3,8,9,10-tetrahydroxy-6-methyl-1,2,3,4-tetrahydroanthracen-1-one + NADP(+)

Direction not assertedBalancedRhea 64292

(4S,8R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,16,19-heptaen-18-one + NADPH + H(+) = (4S,8R,16R)-2,13,16,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.0(3,10).0(4,8).0(14,19)]icosa-1(12),2,5,10,13,19-hexaen-18-one + NADP(+)

Direction not assertedBalancedRhea 64296

3-phenylpropylamine + pyruvate = 3-phenylpropanal + L-alanine

Direction not assertedBalancedRhea 64300

1-phenylpropylamine + pyruvate = 1-phenylpropan-1-one + L-alanine

Direction not assertedBalancedRhea 64304

3-aminobutanoate + pyruvate = acetoacetate + L-alanine

Direction not assertedBalancedRhea 64308

sulochrin + 2 FADH2 + 2 chloride + 2 O2 = dihydrogeodin + 2 FAD + 4 H2O + H(+)

Direction not assertedBalancedRhea 64312

2 dihydrogeodin + O2 + 2 H(+) = 2 (+)-geodin + 2 H2O

Direction not assertedBalancedRhea 64316

(9Z)-hexadecenoyl-CoA + cholesterol = cholesteryl (9Z)-hexadecenoate + CoA

Left to rightBalancedRhea 64320

(11Z)-octadecenoyl-CoA + cholesterol = cholesteryl (11Z)-octadecenoate + CoA

Left to rightBalancedRhea 64324

(7Z)-octadecenoyl-CoA + cholesterol = cholesteryl (7Z)-octadecenoate + CoA

Left to rightBalancedRhea 64328

nicotinate + ATP + CoA = nicotinyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 64332

nicotinyl-CoA + 2 malonyl-CoA + H(+) = 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 64336

4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + (2E,6E)-farnesyl diphosphate = 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + diphosphate

Direction not assertedBalancedRhea 64340

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