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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,251–1,300 of 18,558 reactions from Rhea

5beta-cholestane-3alpha,7alpha-diol + reduced [NADPH--hemoprotein reductase] + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 15261
3-amino-2-oxopropyl phosphate + 1-deoxy-D-xylulose 5-phosphate = pyridoxine 5'-phosphate + phosphate + 2 H2O + H(+)
Direction not assertedBalancedRhea 15265
L-xylo-hex-3-ulonolactone = L-ascorbate + H(+)
Direction not assertedBalancedRhea 15269
L-dopa + 2-oxoglutarate = 3-(3,4-dihydroxyphenyl)pyruvate + L-glutamate
Direction not assertedBalancedRhea 15273
L-lysyl-[alpha-tubulin] + acetyl-CoA = N(6)-acetyl-L-lysyl-[alpha-tubulin] + CoA + H(+)
Direction not assertedBalance undeterminableRhea 15277
lathosterol = 5alpha-cholest-8-en-3beta-ol
Left to rightBalancedRhea 15281

dimethylallyl diphosphate + AMP = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate

Direction not assertedBalancedRhea 15285

[(1->4)-beta-D-xylan](n) + UDP-alpha-D-xylose = [(1->4)-beta-D-xylan](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 15289

3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose = 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 15297

D-apiitol + NAD(+) = aldehydo-D-apiose + NADH + H(+)

Direction not assertedBalancedRhea 15301

betaine aldehyde + NAD(+) + H2O = glycine betaine + NADH + 2 H(+)

Left to rightBalancedRhea 15305

(2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] = biliverdin IXalpha + 4 reduced [2Fe-2S]-[ferredoxin] + 4 H(+)

Direction not assertedBalance undeterminableRhea 15309

ethanolamine = acetaldehyde + NH4(+)

Direction not assertedBalancedRhea 15313

a 2-deoxy-alpha-D-glucoside + H2O = 2-deoxy-D-glucose + an alcohol

Direction not assertedBalance undeterminableRhea 15317

(6aR,11aR)-3,9-dihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 15321

sn-glycerol 3-phosphate + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphate + CoA

Left to rightBalance undeterminableRhea 15325

(S)-ureidoglycolate + NAD(+) = N-carbamoyl-2-oxoglycine + NADH + H(+)

Direction not assertedBalancedRhea 15329

(S)-ureidoglycolate + NADP(+) = N-carbamoyl-2-oxoglycine + NADPH + H(+)

Direction not assertedBalancedRhea 15333

phenylglyoxylyl-CoA + H2O = phenylglyoxylate + CoA + H(+)

Direction not assertedBalancedRhea 15337

hydrogenobyrinate a,c-diamide + Co(2+) + ATP + H2O = cob(II)yrinate a,c diamide + ADP + phosphate + 5 H(+)

Direction not assertedBalancedRhea 15341

L-tyrosine + L-arginine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 15345

N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine

Direction not assertedBalancedRhea 15349

all-trans-violaxanthin + L-ascorbate = all-trans-antheraxanthin + L-dehydroascorbate + H2O

Direction not assertedBalancedRhea 15353

5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose = demethyllactenocin + dTDP + H(+)

Direction not assertedBalancedRhea 15357

a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-xylose = a di-trans,poly-cis-dolichyl D-xylosyl phosphate + UDP

Direction not assertedBalance undeterminableRhea 15361

3-O-[(D-ribitylphospho)2-3-N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-O-6-phospho-alpha-D-mannosyl]-L-seryl-[protein] + UDP-alpha-D-xylose = 3-O-[beta-D-xylosyl-(1->4)-(D-ribitylphospho)2-3-N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-O-6-phospho-alpha-D-mannosyl]-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 15365

2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H(+)

Direction not assertedBalancedRhea 15369

columbamine + S-adenosyl-L-methionine = palmatine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15373

(S)-4,5-dihydroxypentane-2,3-dione + ATP = (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H(+)

Direction not assertedBalancedRhea 15377

quercetin + O2 = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO

Direction not assertedBalancedRhea 15381

L-asparagine = 3-cyano-L-alanine + H2O

Direction not assertedBalancedRhea 15385

ATP = 3',5'-cyclic AMP + diphosphate

Direction not assertedBalancedRhea 15389

(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate

Direction not assertedBalancedRhea 15393

dichloromethane + H2O = formaldehyde + 2 chloride + 2 H(+)

Direction not assertedBalancedRhea 15397

a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP

Left to rightBalance undeterminableRhea 15401

(3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) = [(3R)-hydroxybutanoate](n+1) + CoA

Direction not assertedBalance undeterminableRhea 15405

a 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphoethanolamine = a 1-O-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a 1-O-alkyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 15409

(2R,3R)-tartrate = oxaloacetate + H2O

Direction not assertedBalancedRhea 15413

L-arogenate + NADP(+) = L-tyrosine + CO2 + NADPH

Direction not assertedBalancedRhea 15417

a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate

Left to rightBalance undeterminableRhea 15421

coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 5'-deoxyadenosine + 2 L-methionine + 2 CO2

Direction not assertedBalancedRhea 15425

2 reduced [flavodoxin] + heme b + 2 S-adenosyl-L-methionine = anaerobilin + 2 oxidized [flavodoxin] + Fe(2+) + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 15429

(2S)-naringenin + dimethylallyl diphosphate = sophoraflavanone B + diphosphate

Direction not assertedBalancedRhea 15433

a long-chain fatty aldehyde + NADP(+) + CoA = a long-chain fatty acyl-CoA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 15437

O-carbamoyl-L-serine + H2O + H(+) = pyruvate + 2 NH4(+) + CO2

Direction not assertedBalancedRhea 15445

homogentisate + O2 = 4-maleylacetoacetate + H(+)

Left to rightBalancedRhea 15449

sarcosine + S-adenosyl-L-methionine = N,N-dimethylglycine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 15453

cis-1,2-dihydrobenzene-1,2-diol + NAD(+) = catechol + NADH + H(+)

Direction not assertedBalancedRhea 15457

alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 15461

sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)

Left to rightBalancedRhea 15465

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