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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

12,751–12,800 of 18,558 reactions from Rhea

alpha-D-xylose = beta-D-xylose
Direction not assertedBalancedRhea 63336
L-amino acyl-L-seryl-[protein] + ATP = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 63340
L-amino acyl-L-threonyl-[protein] + ATP = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 63344
L-amino acyl-L-cysteinyl-[protein] + ATP = (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + ADP + phosphate + H(+)
Direction not assertedBalance undeterminableRhea 63348
octadecanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O
Direction not assertedBalance undeterminableRhea 63352
(1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2

? Direction not asserted

Balance undeterminable

Rhea 63356

(S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-oxazole-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 63360

(S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + O2 = (S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 63364

spermine(out) + ATP + H2O = spermine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 63368

L-cysteinyl-[protein] + an acyl-CoA = an S-acyl-L-cysteinyl-[protein] + CoA

Direction not assertedBalance undeterminableRhea 63372

an omega-methyl-ultra-long-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-hydroxy-ultra-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 63376

a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + phosphocholine + H(+)

Left to rightBalance undeterminableRhea 63380

1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + phosphocholine + H(+)

Left to rightBalancedRhea 63384

Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2

Left to rightBalancedRhea 63388

Fe(II)-heme o + A + H2O = Fe(II)-heme i + AH2

Direction not assertedBalancedRhea 63392

Fe(II)-heme i + A + H2O = Fe(II)-hydroxyheme i + AH2

Direction not assertedBalancedRhea 63396

Fe(II)-hydroxyheme i = Fe(II)-heme a + H2O

Direction not assertedBalancedRhea 63400

3,6-dichloropyridine-2,5-diol + FADH2 + O2 = 6-chloro-3-hydroxypyridine-2,5-dione + FAD + chloride + H2O + 2 H(+)

Direction not assertedBalancedRhea 63404

6-chloropyridine-2,3,5-triol + FADH2 + O2 = 3,6-dihydroxypyridine-2,5-dione + FAD + chloride + H2O + 3 H(+)

Direction not assertedBalancedRhea 63408

2,4,6-trichlorophenol + FADH2 + O2 = 2,6-dichlorobenzoquinone + FAD + chloride + H2O + H(+)

Direction not assertedBalancedRhea 63412

2,6-dichlorohydroquinone + FADH2 + O2 = 2-chloro-6-hydroxy-1,4-benzoquinone + FAD + chloride + H2O + 2 H(+)

Direction not assertedBalancedRhea 63416

2-hydroxyethylphosphonate + CTP = cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate

Direction not assertedBalancedRhea 63420

(2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate

Direction not assertedBalancedRhea 63424

levoglucosan + ATP + H2O = D-glucose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 63428

1,2,3-tri-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 63432

1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O = 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+)

Direction not assertedBalancedRhea 63436

(2R)-3-phosphoglycerate + GTP + H(+) = 3-[(R)-glyceryl]-diphospho-5'-guanosine + diphosphate

Direction not assertedBalancedRhea 63440

(2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = oxidized coenzyme F420-0 + GMP + H(+)

Direction not assertedBalancedRhea 63444

(2-aminoethyl)phosphonate + CTP = CMP-(2-aminoethyl)phosphonate + diphosphate

Direction not assertedBalancedRhea 63448

3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = oxidized 3PG-factor420-0 + GMP + H(+)

Direction not assertedBalancedRhea 63452

(2E,6E,10E)-geranylgeraniol + CTP = (2E,6E,10E)-geranylgeranyl phosphate + CDP + H(+)

Direction not assertedBalancedRhea 63456

(2E,6E,10E)-geranylgeraniol + GTP = (2E,6E,10E)-geranylgeranyl phosphate + GDP + H(+)

Direction not assertedBalancedRhea 63460

(2E,6E,10E)-geranylgeraniol + UTP = (2E,6E,10E)-geranylgeranyl phosphate + UDP + H(+)

Direction not assertedBalancedRhea 63464

all-trans-octaprenol + ATP = all-trans-octaprenyl phosphate + ADP + H(+)

Direction not assertedBalancedRhea 63468

all-trans-hexaprenol + ATP = all-trans-hexaprenyl phosphate + ADP + H(+)

Direction not assertedBalancedRhea 63472

prostaglandin E2 + NADP(+) = 15-oxoprostaglandin E2 + NADPH + H(+)

Left to rightBalancedRhea 63476

prostaglandin F2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)

Left to rightBalancedRhea 63480

L-prolyl-[protein] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[protein] + succinate + CO2

Left to rightBalance undeterminableRhea 63484

9,10-phenanthroquinone + NADPH + H(+) = phenanthrene-9,10-diol + NADP(+)

Direction not assertedBalancedRhea 63488

menadione + NADPH + H(+) = menadiol + NADP(+)

Direction not assertedBalancedRhea 63492

4-nitrobenzaldehyde + NADPH + H(+) = 4-nitrobenzyl alcohol + NADP(+)

Direction not assertedBalancedRhea 63496

S-nitrosoglutathione + NADPH + H(+) = S-(hydroxysulfenamide)glutathione + NADP(+)

Direction not assertedBalancedRhea 63500

daunorubicin + NADPH + H(+) = 13-dihydrodaunorubicin + NADP(+)

Left to rightBalancedRhea 63504

a 1,2-saturated fatty acid + O2 = a (2R)-2-hydroperoxy fatty acid

Direction not assertedBalance undeterminableRhea 63508

biphenyl-2,2'-diol + NADH + O2 + H(+) = biphenyl-2,2',3-triol + NAD(+) + H2O

Direction not assertedBalancedRhea 63512

biphenyl-2,2',3-triol + NADH + O2 + H(+) = biphenyl-2,2',3,3'-tetraol + NAD(+) + H2O

Direction not assertedBalancedRhea 63516

2-isopropylphenol + NADH + O2 + H(+) = 3-isopropylcatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 63520

2-propylphenol + NADH + O2 + H(+) = 3-propylcatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 63524

[thioredoxin]-dithiol + H2O2 = [thioredoxin]-disulfide + 2 H2O

Direction not assertedBalance undeterminableRhea 63528

angiotensin I + H2O = angiotensin-(1-9) + L-leucine

Left to rightBalancedRhea 63532

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