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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

12,701–12,750 of 12,877 reactions from Human-GEM

10-HETE[n] + NAD+[n] = H+[n] + NADH[n] + 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate[n]
Left to rightBalancedEC 1.1.1.105Retinol metabolismHuman-GEM MAR20007
10-HETE[c] + NAD+[c] = H+[c] + NADH[c] + 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate[c]
Left to rightUnbalancedEC 1.1.1.-Retinol metabolismHuman-GEM MAR20008
H+[n] + NADH[n] + 1,4-benzoquinone[n] = NAD+[n] + hydroquinone[n]
Left to rightBalancedEC 1.1.1.328, 1.11.1.1, 1.6.5.2IsolatedHuman-GEM MAR20009
H+[c] + NADH[c] + 1,4-benzoquinone[c] = NAD+[c] + hydroquinone[c]
Left to rightBalancedEC 1.1.1.328, 1.11.1.1, 1.6.5.2IsolatedHuman-GEM MAR20010
H2O[n] + NAD+[n] + retinal[n] = 2 H+[n] + NADH[n] + retinoate[n]
Left to rightBalancedEC 1.2.1.36Retinol metabolism

Human-GEM MAR20011

AKG[m] + (S)-3-hydroxybutanoate[m] = acetoacetate[m] + (R)-2-hydroxyglutarate[m]

Left to rightBalancedEC 1.1.99.24IsolatedHuman-GEM MAR20013

2 H+[c] + NADH[c] + palmitate[c] = H2O[c] + hexadecanal[c] + NAD+[c]

Left to rightBalancedEC 1.2.1.48Fatty acid metabolismHuman-GEM MAR20016

H2O[c] + NAD+[c] + octanal[c] = 2 H+[c] + NADH[c] + octanoic acid[c]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5octane oxidationHuman-GEM MAR20017

NADP+[g] + 13,14-dihydro-15-oxo-prostaglandin E2[g] = H+[g] + NADPH[g] + 15-oxoprostaglandin E2[g]

Left to rightBalancedEC 1.3.1.48Arachidonic acid metabolismHuman-GEM MAR20018

NADP+[n] + 13,14-dihydro-15-oxo-prostaglandin E2[n] = H+[n] + NADPH[n] + 15-oxoprostaglandin E2[n]

Left to rightBalancedEC 1.3.1.48Arachidonic acid metabolismHuman-GEM MAR20019

mead acid[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate[r]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20021

mead acid[i] + O2[i] + FMNH2[i] = FMN[i] + H2O[i] + 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate[i]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20022

EPA[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate[r]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20023

EPA[i] + O2[i] + FMNH2[i] = FMN[i] + H2O[i] + 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate[i]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20024

DHA[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate[r]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20025

DHA[i] + O2[i] + FMNH2[i] = FMN[i] + H2O[i] + 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate[i]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20026

lauric acid[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 11-hydroxydodecanoate[r]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20027

lauric acid[i] + O2[i] + FMNH2[i] = FMN[i] + H2O[i] + 11-hydroxydodecanoate[i]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20028

myristic acid[r] + O2[r] + FMNH2[r] = FMN[r] + H2O[r] + 13-hydroxytetradecanoate[r]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20029

myristic acid[i] + O2[i] + FMNH2[i] = FMN[i] + H2O[i] + 13-hydroxytetradecanoate[i]

Left to rightBalancedEC 1.14.14.1Fatty acid metabolismHuman-GEM MAR20030

H+[r] + NADPH[r] + O2[r] + PNP[r] = 4-nitrocatechol[r] + H2O[r] + NADP+[r]

Left to rightBalancedEC 1.14.13.n7Fatty acid metabolismHuman-GEM MAR20031

H+[i] + NADPH[i] + O2[i] + PNP[i] = 4-nitrocatechol[i] + H2O[i] + NADP+[i]

Left to rightBalancedEC 1.14.13.n7Fatty acid metabolismHuman-GEM MAR20032

galactose[n] = beta-D-galactose[n]

Left to rightBalancedEC 5.1.3.3Galactose metabolismHuman-GEM MAR20033

galactose[c] = beta-D-galactose[c]

Left to rightBalancedEC 5.1.3.3Galactose metabolismHuman-GEM MAR20034

alpha-D-glucose[n] = beta-D-glucose[n]

Left to rightBalancedEC 5.1.3.3Glycolysis / GluconeogenesisHuman-GEM MAR20035

alpha-D-glucose[c] = beta-D-glucose[c]

Left to rightBalancedEC 5.1.3.3Glycolysis / GluconeogenesisHuman-GEM MAR20036

H2O[c] + NADP+[c] + octanal[c] = 2 H+[c] + NADPH[c] + octanoic acid[c]

Left to rightBalancedEC 1.2.1.3, 1.2.1.5Glycolysis / GluconeogenesisHuman-GEM MAR20037

H2O[c] + NADP+[c] + benzaldehyde[c] = benzoate[c] + 2 H+[c] + NADPH[c]

Left to rightBalancedEC 1.2.1.7Toluene degradationHuman-GEM MAR20038

H2O[c] + NAD+[c] + benzaldehyde[c] = benzoate[c] + 2 H+[c] + NADH[c]

Left to rightBalancedEC 1.2.1.28Toluene degradationHuman-GEM MAR20039

H2O[c] + NADP+[c] + hexanal[c] = 2 H+[c] + hexanoic acid[c] + NADPH[c]

Left to rightBalancedEC 1.2.1.3, 1.2.1.5Glycolysis / GluconeogenesisHuman-GEM MAR20040

4-hydroxy-2-nonenal[c] + H2O[c] + NADP+[c] = 2 H+[c] + NADPH[c] + (E)-4-hydroxynon-2-enoate[c]

Left to rightBalancedEC 1.2.1.-Glycolysis / GluconeogenesisHuman-GEM MAR20041

H2O[c] + NADP+[c] + (2E)-octenal[c] = 2 H+[c] + NADPH[c] + (2E)-octenoate[c]

Left to rightBalancedEC 1.2.1.5Glycolysis / GluconeogenesisHuman-GEM MAR20042

H2O[c] + NAD+[c] + (2E)-octenal[c] = 2 H+[c] + NADH[c] + (2E)-octenoate[c]

Left to rightBalancedEC 1.2.1.-Glycolysis / GluconeogenesisHuman-GEM MAR20043

hydroxymethylglutathione[c] + NADP+[c] = formylglutathione[c] + H+[c] + NADPH[c]

Left to rightBalancedEC 1.1.1.284IsolatedHuman-GEM MAR20044

H2O[r] + hexadecenal[r] + NAD+[r] = 2 H+[r] + NADH[r] + (E)-hexadec-2-enoate[r]

Left to rightBalancedEC 1.2.1.3Fatty acid metabolismHuman-GEM MAR20046

H2O[c] + hexadecenal[c] + NAD+[c] = 2 H+[c] + NADH[c] + (E)-hexadec-2-enoate[c]

Left to rightBalancedEC 1.2.1.3Fatty acid metabolismHuman-GEM MAR20047

2 H+[r] + NADH[r] + palmitate[r] = H2O[r] + hexadecanal[r] + NAD+[r]

Left to rightBalancedEC 1.2.1.48Fatty acid metabolismHuman-GEM MAR20048

H2O[r] + NAD+[r] + 22-oxodocosanoate[r] = 2 H+[r] + NADH[r] + docosanedioic acid[r]

Left to rightBalancedEC 1.2.1.-Fatty acid metabolismHuman-GEM MAR20049

H2O[c] + NAD+[c] + 22-oxodocosanoate[c] = 2 H+[c] + NADH[c] + docosanedioic acid[c]

Left to rightBalancedEC 1.2.1.-Fatty acid metabolismHuman-GEM MAR20050

2(S)-pristanal[r] + H2O[r] + NAD+[r] = 2 H+[r] + NADH[r] + pristanic acid[r]

Left to rightBalancedEC 1.2.1.-Fatty acid metabolismHuman-GEM MAR20051

H2O[r] + NAD+[r] + octadecanal[r] = 2 H+[r] + NADH[r] + stearate[r]

Left to rightBalancedEC 1.2.1.48Fatty acid metabolismHuman-GEM MAR20053

H2O[c] + NAD+[c] + octadecanal[c] = 2 H+[c] + NADH[c] + stearate[c]

Left to rightBalancedEC 1.2.1.48Fatty acid metabolismHuman-GEM MAR20054

2 H+[r] + lauric acid[r] + NADH[r] = H2O[r] + NAD+[r] + dodecanal[r]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20055

2 H+[c] + lauric acid[c] + NADH[c] = H2O[c] + NAD+[c] + dodecanal[c]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20056

H2O[r] + NAD+[r] + decanal[r] = decanoic acid[r] + 2 H+[r] + NADH[r]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20057

H2O[c] + NAD+[c] + decanal[c] = decanoic acid[c] + 2 H+[c] + NADH[c]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20058

H2O[r] + NAD+[r] + tetradecanal[r] = 2 H+[r] + myristic acid[r] + NADH[r]

Left to rightBalancedEC 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20059

H2O[c] + NAD+[c] + tetradecanal[c] = 2 H+[c] + myristic acid[c] + NADH[c]

Left to rightBalancedEC 1.2.1.48, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20060

H2O[r] + NAD+[r] + octanal[r] = 2 H+[r] + NADH[r] + octanoic acid[r]

Left to rightBalancedEC 1.2.1.3, 1.2.1.48, 1.2.1.5octane oxidationHuman-GEM MAR20061

H2O[r] + NAD+[r] + heptanal[r] = 2 H+[r] + heptylic acid[r] + NADH[r]

Left to rightBalancedEC 1.2.1.3, 1.2.1.5Fatty acid metabolismHuman-GEM MAR20062

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