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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

12,551–12,600 of 18,558 reactions from Rhea

digoxigenin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydrodigoxigenin + 2 Fe(III)-[cytochrome c]
Direction not assertedBalance undeterminableRhea 62536
ouabain + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydroouabain + 2 Fe(III)-[cytochrome c]
Direction not assertedBalance undeterminableRhea 62540
ouabagenin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydroouabagenin + 2 Fe(III)-[cytochrome c]
Direction not assertedBalance undeterminableRhea 62544
a neolactoside IV(3)-beta-GlcNAc-nLc4Cer + UDP-alpha-D-galactose = a neolactoside nLc6Cer + UDP + H(+)
Left to rightBalance undeterminableRhea 62548
a beta-D-glucosylceramide + UDP-alpha-D-galactose = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP + H(+)
Left to rightBalance undeterminableRhea 62552
3,4-dihydroxyphenylacetate + H(+) = 4-methylcatechol + CO2
Direction not assertedBalancedRhea 62556

(4R)-limonene + A + H2O = (4R)-perillyl alcohol + AH2

Direction not assertedBalancedRhea 62560

(4S)-limonene + A + H2O = (4S)-perillyl alcohol + AH2

Direction not assertedBalancedRhea 62564

S-benzyl-L-cysteinylglycine + H2O = S-benzyl-L-cysteine + glycine

Left to rightBalancedRhea 62568

S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteinylglycine + H2O = S-(1-hydroxy-3-methylhexan-3-yl)-L-cysteine + glycine

Direction not assertedBalancedRhea 62572

L-cystine(out) + ATP + H2O = L-cystine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 62576

D-cystine(out) + ATP + H2O = D-cystine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 62580

L-tyrosine(out) + ATP + H2O = L-tyrosine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 62584

2-hydroxy-2-(4-hydroxyphenyl)acetate + H(+) = 4-hydroxybenzyl alcohol + CO2

Direction not assertedBalancedRhea 62588

(S)-8-oxocitronellyl enol + NADP(+) = (6E)-8-oxogeranial + NADPH + H(+)

Direction not assertedBalancedRhea 62592

(S)-8-oxocitronellyl enol + NAD(+) = (6E)-8-oxogeranial + NADH + H(+)

Direction not assertedBalancedRhea 62596

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate

Left to rightBalancedRhea 62600

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 7-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate

Direction not assertedBalancedRhea 62604

ubiquinone-10 + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + ubiquinol-10

Left to rightBalancedRhea 62608

adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine = N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 62612

a lactoside III(4)-a-Fuc-Lc4Cer + GDP-beta-L-fucose = a lactoside IV(2),III(4)-a-[Fuc]2-Lc4Cer + GDP + H(+)

Left to rightBalance undeterminableRhea 62616

a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O

Direction not assertedBalance undeterminableRhea 62620

[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O

Direction not assertedBalance undeterminableRhea 62624

a hydroperoxide + NADH + H(+) = an alcohol + NAD(+) + H2O

Direction not assertedBalance undeterminableRhea 62628

a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O

Left to rightBalance undeterminableRhea 62632

N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O

Direction not assertedBalance undeterminableRhea 62636

[mycoredoxin]-L-dithiol + a hydroperoxide = [mycoredoxin]-L-disulfide + an alcohol + H2O

Direction not assertedBalance undeterminableRhea 62640

(5Z,8Z)-eicosadienoate + O2 = (5S)-hydroperoxy-(6E,8Z)-eicosadienoate

Direction not assertedBalancedRhea 62644

(12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate

Direction not assertedBalancedRhea 62648

6 malonyl-CoA + acetyl-CoA + 6 H(+) = naphtopyrone YWA1 + 6 CO2 + 7 CoA + H2O

Direction not assertedBalancedRhea 62652

2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + dimethylallyl diphosphate = 2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol + diphosphate

Direction not assertedBalancedRhea 62656

2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol = (2'R)-atrovenetin

Direction not assertedBalancedRhea 62660

(2'R)-atrovenetin + S-adenosyl-L-methionine = deoxyherqueinone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 62664

deoxyherqueinone + NADPH + O2 + H(+) = herqueinone + NADP(+) + H2O

Direction not assertedBalancedRhea 62668

a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 62672

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-thiocarboxamide + 10-formyldihydrofolate = 6-thio-IMP + 7,8-dihydrofolate + H2O

Left to rightBalancedRhea 62676

naphtopyrone YWA1 = norrubrofusarin + H2O + H(+)

Direction not assertedBalancedRhea 62680

norrubrofusarin + S-adenosyl-L-methionine = rubrofusarin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 62684

4 norrubrofusarin + O2 = 2 ustilaginoidin A + 2 H2O

Direction not assertedBalancedRhea 62688

2 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + O2 = 2 tellimagrandin II + 2 H2O + 2 H(+)

Direction not assertedBalancedRhea 62692

4 tellimagrandin II + O2 = 2 cornusiin E + 2 H2O

Direction not assertedBalancedRhea 62696

naphtopyrone YWA1 + H2O = naphthalene-1,3,6,8-tetrol + acetoacetate + H(+)

Direction not assertedBalancedRhea 62700

glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine

Direction not assertedBalancedRhea 62704

(indol-3-yl)butanoate + UDP-alpha-D-glucose = 4-(indol-3-yl)butanoyl-beta-D-glucose + UDP

Direction not assertedBalancedRhea 62708

betaenone C + NADPH + O2 + H(+) = stemphyloxin I + NADP(+) + H2O

Direction not assertedBalancedRhea 62712

stemphyloxin I = stemphyloxin II

Direction not assertedBalancedRhea 62716

probetaenone I + 3 NADPH + 3 O2 + 3 H(+) = betaenone B + 3 NADP(+) + 3 H2O

Direction not assertedBalancedRhea 62720

(+)-premalbrancheamide + bromide + FADH2 + O2 = (+)-isomalbrancheamide C + FAD + 2 H2O

Direction not assertedBalancedRhea 62724

(+)-malbrancheamide B + bromide + FADH2 + O2 = (+)-malbrancheamide D + FAD + 2 H2O

Direction not assertedBalancedRhea 62728

(+)-isomalbrancheamide B + bromide + FADH2 + O2 = (+)-isomalbrancheamide D + FAD + 2 H2O

Direction not assertedBalancedRhea 62732

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