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1,201–1,250 of 12,877 reactions from Human-GEM
12-keto-LTB4[c] + H+[c] + NADH[c] = 10,11-dihydro-12-oxo-LTB4[c] + NAD+[c]
Left to rightBalancedEC 1.3.1.-Leukotriene metabolismHuman-GEM MAR01228
12-keto-LTB4[m] + H+[m] + NADH[m] = 10,11-dihydro-12-oxo-LTB4[m] + NAD+[m]
Left to rightBalancedEC 1.3.1.-Leukotriene metabolismHuman-GEM MAR01229
12-keto-LTB4[x] + H+[x] + NADH[x] = 10,11-dihydro-12-oxo-LTB4[x] + NAD+[x]
Left to rightBalancedEC 1.3.1.-Leukotriene metabolismHuman-GEM MAR01230
10,11-dihydro-12-oxo-LTB4[c] + H+[c] + NADPH[c] = 10,11-dihydro-LTB4[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01231
10,11-dihydro-12-oxo-LTB4[m] + H+[m] + NADPH[m] = 10,11-dihydro-LTB4[m] + NADP+[m]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01232
10,11-dihydro-12-oxo-LTB4[x] + H+[x] + NADPH[x] = 10,11-dihydro-LTB4[x] + NADP+[x]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01233
10,11-dihydro-LTB4[c] + H+[c] + NADPH[c] + O2[c] = 20-OH-10,11-dihydro-LTB4[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01234
10,11-dihydro-LTB4[r] + H+[r] + NADPH[r] + O2[r] = 20-OH-10,11-dihydro-LTB4[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01235
20-OH-10,11-dihydro-LTB4[c] + H+[c] + NADPH[c] + O2[c] = 10,11-dihydro-20-dihydroxy-LTB4[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01236
20-OH-10,11-dihydro-LTB4[r] + H+[r] + NADPH[r] + O2[r] = 10,11-dihydro-20-dihydroxy-LTB4[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01237
10,11-dihydro-20-dihydroxy-LTB4[c] + H+[c] + NADPH[c] + O2[c] = 10,11-dihydro-20-trihydroxy-LTB4[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01238
10,11-dihydro-20-dihydroxy-LTB4[r] + H+[r] + NADPH[r] + O2[r] = 10,11-dihydro-20-trihydroxy-LTB4[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Leukotriene metabolismHuman-GEM MAR01239
10,11-dihydro-20-trihydroxy-LTB4[r] = 10,11-dihydro-20-trihydroxy-LTB4[c]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01240
10,11-dihydro-20-trihydroxy-LTB4[c] = 20-COOH-10,11-dihydro-LTB4[c] + H+[c] + H2O[c]
ReversibleBalancedLeukotriene metabolismHuman-GEM MAR01241
20-COOH-10,11-dihydro-LTB4[c] = 20-COOH-10,11-dihydro-LTB4[x]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01242
20-COOH-10,11-dihydro-LTB4[c] = 20-COOH-10,11-dihydro-LTB4[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01243
20-COOH-10,11-dihydro-LTB4[c] + NADP+[c] = 20-COOH-LTB4[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01244
20-COOH-10,11-dihydro-LTB4[m] + NADP+[m] = 20-COOH-LTB4[m] + H+[m] + NADPH[m]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01245
20-COOH-10,11-dihydro-LTB4[x] + NADP+[x] = 20-COOH-LTB4[x] + H+[x] + NADPH[x]
Left to rightBalancedEC 1.1.1.184Leukotriene metabolismHuman-GEM MAR01246
20-COOH-LTB4[m] + CoA[m] + FAD[m] + H2O[m] + NAD+[m] = 18-COOH-LTB4[m] + acetyl-CoA[m] + FADH2[m] + H+[m] + NADH[m]
Left to rightBalancedLeukotriene metabolismHuman-GEM MAR01247
20-COOH-LTB4[c] + ATP[c] + CoA[c] = 20-CoA-20-oxo-LTB4[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01248
20-COOH-LTB4[m] + ATP[m] + CoA[m] = 20-CoA-20-oxo-LTB4[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01249
20-COOH-LTB4[r] + ATP[r] + CoA[r] = 20-CoA-20-oxo-LTB4[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01250
20-COOH-LTB4[x] + ATP[x] + CoA[x] = 20-CoA-20-oxo-LTB4[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01251
20-CoA-20-oxo-LTB4[c] = 20-CoA-20-oxo-LTB4[r]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR01252
20-CoA-20-oxo-LTB4[m] + O2[m] = (18E)-20-oxo-20-CoA-LTB4[m] + H2O2[m]
Left to rightBalancedEC 1.3.3.6Leukotriene metabolismHuman-GEM MAR01253
20-CoA-20-oxo-LTB4[x] + FAD[x] = (18E)-20-oxo-20-CoA-LTB4[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Leukotriene metabolismHuman-GEM MAR01254
(18E)-20-oxo-20-CoA-LTB4[m] + H2O[m] = 20-CoA-20-oxo-18r-hydroxy-LTB4[m]
Left to rightBalancedEC 4.2.1.17Leukotriene metabolismHuman-GEM MAR01255
(18E)-20-oxo-20-CoA-LTB4[x] + H2O[x] = 20-CoA-20-oxo-18r-hydroxy-LTB4[x]
Left to rightBalancedEC 4.2.1.17Leukotriene metabolismHuman-GEM MAR01256
20-CoA-20-oxo-18r-hydroxy-LTB4[m] + NAD+[m] = 18,20-dioxo-20-CoA-LTB4[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01257
20-CoA-20-oxo-18r-hydroxy-LTB4[x] + NAD+[x] = 18,20-dioxo-20-CoA-LTB4[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01258
18,20-dioxo-20-CoA-LTB4[m] + CoA[m] = 18-CoA-18-oxo-dinor-LTB4[m] + acetyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01259
18,20-dioxo-20-CoA-LTB4[x] + CoA[x] = 18-CoA-18-oxo-dinor-LTB4[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Leukotriene metabolismHuman-GEM MAR01260
18-CoA-18-oxo-dinor-LTB4[m] + H2O[m] = CoA[m] + H+[m] + omega-carboxy-trinor-LTB4[m]
Left to rightBalancedEC 3.1.2.2Leukotriene metabolismHuman-GEM MAR01261
18-CoA-18-oxo-dinor-LTB4[x] + H2O[x] = CoA[x] + H+[x] + omega-carboxy-trinor-LTB4[x]
Left to rightBalancedEC 3.1.2.2Leukotriene metabolismHuman-GEM MAR01262
10,11-dihydro-LTB4[c] + ATP[c] + CoA[c] = 10,11-dihydro-LTB4-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01263
10,11-dihydro-LTB4[m] + ATP[m] + CoA[m] = 10,11-dihydro-LTB4-CoA[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01264
10,11-dihydro-LTB4[r] + ATP[r] + CoA[r] = 10,11-dihydro-LTB4-CoA[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01265
10,11-dihydro-LTB4[x] + ATP[x] + CoA[x] = 10,11-dihydro-LTB4-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Leukotriene metabolismHuman-GEM MAR01266
10,11-dihydro-LTB4-CoA[c] = 10,11-dihydro-LTB4-CoA[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01267
10,11-dihydro-LTB4-CoA[c] = 10,11-dihydro-LTB4-CoA[x]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01268
10,11-dihydro-LTB4-CoA[c] = 10,11-dihydro-LTB4-CoA[r]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR01269
10,11-dihydro-LTB4-CoA[m] + O2[m] = 5(S),12(R)-dihydroxy-eicosa-2,8-trans-6,14-cis-tetraenoyl-CoA[m] + H2O2[m]
Left to rightBalancedEC 1.3.3.6Leukotriene metabolismHuman-GEM MAR01270
10,11-dihydro-LTB4-CoA[x] + FAD[x] = 5(S),12(R)-dihydroxy-eicosa-2,8-trans-6,14-cis-tetraenoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Leukotriene metabolismHuman-GEM MAR01271
5(S),12(R)-dihydroxy-eicosa-2,8-trans-6,14-cis-tetraenoyl-CoA[m] + H2O[m] = 3(S),5(S),12(R)-trihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Leukotriene metabolismHuman-GEM MAR01272
5(S),12(R)-dihydroxy-eicosa-2,8-trans-6,14-cis-tetraenoyl-CoA[x] + H2O[x] = 3(S),5(S),12(R)-trihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Leukotriene metabolismHuman-GEM MAR01273
3(S),5(S),12(R)-trihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[m] + NAD+[m] = 3-oxo-5(S),12(R)-dihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01274
3(S),5(S),12(R)-trihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[x] + NAD+[x] = 3-oxo-5(S),12(R)-dihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01275
3-oxo-5(S),12(R)-dihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[m] + CoA[m] = 3(S),10(R)-OH-octadeca-6-trans-4,12-cis-trienoyl-CoA[m] + acetyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Leukotriene metabolismHuman-GEM MAR01276
3-oxo-5(S),12(R)-dihydroxy-eicosa-8-trans-6,14-cis-trienoyl-CoA[x] + CoA[x] = 3(S),10(R)-OH-octadeca-6-trans-4,12-cis-trienoyl-CoA[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Leukotriene metabolismHuman-GEM MAR01277