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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,951–12,000 of 18,558 reactions from Rhea

a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NAD(+) = a 4alpha-methyl-3-oxosteroid + CO2 + NADH
Direction not assertedBalance undeterminableRhea 60084
a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP(+) = a 4alpha-methyl-3-oxosteroid + CO2 + NADPH
Direction not assertedBalance undeterminableRhea 60088
4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) = 3-dehydro-4alpha-methylzymosterol + CO2 + NADH
Direction not assertedBalancedRhea 60092
4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 3-dehydro-4alpha-methylzymosterol + CO2 + NADPH
Direction not assertedBalancedRhea 60096
cyanidin + UDP-alpha-D-glucose = cyanidin 3-O-beta-D-glucoside + UDP + H(+)
Direction not assertedBalancedRhea 60100
indole-3-propanoate + oxidized [electron-transfer flavoprotein] + H(+) = (E)-3-(indol-3-yl)acrylate + reduced [electron-transfer flavoprotein]
Direction not asserted

Balance undeterminable

Rhea 60104

(R)-3-(4-hydroxyphenyl)lactoyl-CoA = (E)-4-coumaroyl-CoA + H2O

Direction not assertedBalancedRhea 60108

(R)-3-(indol-3-yl)lactoyl-CoA = (E)-3-(indol-3-yl)acryloyl-CoA + H2O

Direction not assertedBalancedRhea 60112

methylphosphonate + 2-oxoglutarate + O2 = hydroxymethylphosphonate + succinate + CO2

Direction not assertedBalancedRhea 60116

(2E,6E)-farnesyl diphosphate + S-adenosyl-L-methionine = pre-sodorifen diphosphate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 60120

pre-sodorifen diphosphate = sodorifen + diphosphate

Direction not assertedBalancedRhea 60124

17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ATP + H2O = 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 60128

a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 = a (8S,9S)-5-glyceryl-2'-deoxycytidine in DNA + glyoxylate + CO2

Direction not assertedBalance undeterminableRhea 60132

a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 = a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + glyoxylate + CO2

Direction not assertedBalance undeterminableRhea 60136

dodecanoyl-CoA + malonyl-CoA + H(+) = 3-oxotetradecanoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 60140

L-glutamyl-[protein] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Left to rightBalance undeterminableRhea 60144

(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Left to rightBalance undeterminableRhea 60148

gamma-L-glutamyl-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + L-glutamate

Left to rightBalance undeterminableRhea 60152

D-galactose(out) + ATP + H2O = D-galactose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 60156

vincristine(in) + ATP + H2O = vincristine(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 60160

a guanosine in RNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in RNA + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 60164

a fatty acid + ATP = a fatty acyl phosphate + ADP

Direction not assertedBalance undeterminableRhea 60168

5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + selenophosphate + H(+) = 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + (2E)-thiogeraniol

Direction not assertedBalancedRhea 60172

5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + H2O = 5-methylaminomethyl-2-selenouridine(34) in tRNA + phosphate

Direction not assertedBalancedRhea 60176

D-fructose(out) + ATP + H2O = D-fructose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 60180

D-glucose(out) + ATP + H2O = D-glucose(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 60184

N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Left to rightBalance undeterminableRhea 60188

N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 60192

N(6)-methyl-L-lysyl(9)-[histone H3] + 2-oxoglutarate + O2 = L-lysyl(9)-[histone H3] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 60196

N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Direction not assertedBalance undeterminableRhea 60200

N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + formaldehyde + succinate + CO2

Left to rightBalance undeterminableRhea 60204

N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2

Direction not assertedBalance undeterminableRhea 60208

N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60212

N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(4)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60216

N(6)-methyl-L-lysyl(4)-[histone H3] + 2-oxoglutarate + O2 = L-lysyl(4)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60220

N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Direction not assertedBalance undeterminableRhea 60224

N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60228

N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2-oxoglutarate + O2 = N(6)-methyl-L-lysyl(27)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60232

N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Direction not assertedBalance undeterminableRhea 60236

N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2-oxoglutarate + O2 = N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 60240

N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2

Left to rightBalance undeterminableRhea 60244

N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + A + H2O = N(6)-methyl-L-lysyl(4)-[histone H3] + formaldehyde + AH2

Left to rightBalance undeterminableRhea 60248

(S)-methylmalonyl-CoA + NADP(+) = acryloyl-CoA + CO2 + NADPH

Direction not assertedBalancedRhea 60252

N(6)-methyl-L-lysyl(4)-[histone H3] + A + H2O = L-lysyl(4)-[histone H3] + formaldehyde + AH2

Left to rightBalance undeterminableRhea 60256

L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Left to rightBalance undeterminableRhea 60260

L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 60264

N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 60268

N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 60272

L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Left to rightBalance undeterminableRhea 60276

L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 60280

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