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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,751–11,800 of 18,558 reactions from Rhea

beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + H2O = N-octadecanoylsphing-4-enine + D-glucose
Left to rightBalancedRhea 59284
beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-glucose
Left to rightBalancedRhea 59288
beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O = N-octadecanoylsphing-4-enine + D-galactose
Left to rightBalancedRhea 59292
an N-acylglycine + 2 L-ascorbate + O2 = an N-acyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O
Direction not assertedBalance undeterminableRhea 59296
firefly D-luciferin + 3'-phosphoadenylyl sulfate = firefly D-sulfoluciferin + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 59300
firefly L-luciferin + 3'-phosphoadenylyl sulfate = firefly L-sulfoluciferin + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 59304

D-galactono-1,5-lactone + H2O = D-galactonate + H(+)

Direction not assertedBalancedRhea 59308

D-galactose + O2 = D-galactono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59312

D-cellobiose + O2 = D-cellobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59316

D-cellobiono-1,5-lactone + H2O = 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)

Direction not assertedBalancedRhea 59320

D-xylose + O2 = D-xylono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59324

D-xylono-1,5-lactone + H2O = D-xylonate + H(+)

Direction not assertedBalancedRhea 59328

1'-hydroxy-gamma-carotene + A = 1'-hydroxytorulene + AH2

Direction not assertedBalancedRhea 59332

1-hydroxy-all-trans-1,2-dihydro-neurosporene + A = demethylspheroidene + AH2

Direction not assertedBalancedRhea 59336

1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A = 1'-hydroxy-demethylspheroidene + AH2

Direction not assertedBalancedRhea 59340

D-maltose + O2 = D-maltobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59344

D-maltobiono-1,5-lactone + H2O = D-maltobionate + H(+)

Direction not assertedBalancedRhea 59348

beta-lactose + O2 = lactobiono-1,5-lactone + H2O2

Direction not assertedBalancedRhea 59352

lactobiono-1,5-lactone + H2O = lactobionate + H(+)

Direction not assertedBalancedRhea 59356

carnosine + H2O = beta-alanine + L-histidine

Left to rightBalancedRhea 59360

1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 9,10-epoxyoctadecanoate + 1-octadecanoyl-sn-glycero-3-phosphoserine + H(+)

Left to rightBalancedRhea 59364

1-octadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + 10-hydroxyoctadecanoate + H(+)

Left to rightBalancedRhea 59368

1-hexadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 10-hydroxyoctadecanoate + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H(+)

Left to rightBalancedRhea 59372

4-amino-4-deoxychorismate = 4-amino-4-deoxyprephenate

Direction not assertedBalancedRhea 59376

4-amino-4-deoxyprephenate + NAD(+) = 3-(4-aminophenyl)pyruvate + CO2 + NADH + H(+)

Direction not assertedBalancedRhea 59380

4-amino-L-phenylalanine + 2-oxoglutarate = 3-(4-aminophenyl)pyruvate + L-glutamate

Direction not assertedBalancedRhea 59384

a fatty acid ester + H2O = an aliphatic alcohol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 59388

L-seryl-[protein] + acetyl-CoA = O-acetyl-L-seryl-[protein] + CoA

Left to rightBalance undeterminableRhea 59392

L-leucine = D-leucine

Direction not assertedBalancedRhea 59396

L-2-aminohexanoate = D-2-aminohexanoate

Direction not assertedBalancedRhea 59400

L-homoserine = D-homoserine

Direction not assertedBalancedRhea 59404

N-acetyl-L-aspartate + H2O = L-aspartate + acetate

Left to rightBalancedRhea 59408

2-oxosuccinamate + H2O = oxaloacetate + NH4(+)

Left to rightBalancedRhea 59412

tryptamine + O2 + H2O = indole-3-acetaldehyde + H2O2 + NH4(+)

Left to rightBalancedRhea 59416

methylamine + O2 + H2O = formaldehyde + H2O2 + NH4(+)

Left to rightBalancedRhea 59420

benzylamine + O2 + H2O = benzaldehyde + H2O2 + NH4(+)

Left to rightBalancedRhea 59424

3-hydroxypropanal + NADP(+) + H2O = 3-hydroxypropanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 59428

3-hydroxypropanal + NAD(+) + H2O = 3-hydroxypropanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 59432

4-amino-L-phenylalanine + holo-[peptidyl-carrier protein] + ATP = 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 59436

(-)-dehydrodiconiferyl alcohol + NADPH + H(+) = (S)-isodihydrodehydrodiconiferyl alcohol + NADP(+)

Direction not assertedBalancedRhea 59440

1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A = 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2

Direction not assertedBalancedRhea 59444

dodecan-1-ol + NADP(+) = dodecanal + NADPH + H(+)

Direction not assertedBalancedRhea 59448

a long-chain primary fatty alcohol + NADP(+) = a long-chain fatty aldehyde + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 59452

tetradecan-1-ol + NADP(+) = tetradecanal + NADPH + H(+)

Direction not assertedBalancedRhea 59456

hexadecan-1-ol + NADP(+) = hexadecanal + NADPH + H(+)

Direction not assertedBalancedRhea 59460

octadecan-1-ol + NADP(+) = octadecanal + NADPH + H(+)

Direction not assertedBalancedRhea 59464

an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate

Left to rightBalance undeterminableRhea 59468

2',3'-cGAMP + H2O = Gp(2'-5')Ap(3') + H(+)

Direction not assertedBalancedRhea 59472

benzoate + L-phenylalanine + 2 AH2 + 2 ATP = N-benzoyl-L-phenylalaninol + 2 A + 2 AMP + 2 diphosphate + H(+)

Direction not assertedBalancedRhea 59476

schleiferon A + O2 = schleiferon B + H2O2 + H(+)

Direction not assertedBalancedRhea 59480

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