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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,701–11,750 of 18,558 reactions from Rhea

2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose = 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)
Direction not assertedBalancedRhea 59084
D-histidine + S-adenosyl-L-methionine = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + S-methyl-5'-thioadenosine + H(+)
Direction not assertedBalancedRhea 59088
[(1->3)-alpha-D-glucosyl](n) + sucrose = [(1->3)-alpha-D-glucosyl](n+1) + D-fructose
Direction not assertedBalance undeterminableRhea 59092
monoglucosyl-enterobactin + UDP-alpha-D-glucose = diglucosyl-enterobactin + UDP + H(+)
Direction not assertedBalancedRhea 59096
diglucosyl-enterobactin + UDP-alpha-D-glucose = triglucosyl-enterobactin + UDP + H(+)
Direction not assertedBalancedRhea 59100
a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + chenodeoxycholate = beta-D-glucosyl-(1->3)-O-chenodeoxycholate + a di-trans,poly-cis-dolichyl phosphate + H(+)

→ Left to right

Balance undeterminable

Rhea 59104

octyl beta-D-glucose + chenodeoxycholate = beta-D-glucosyl-(1->3)-O-chenodeoxycholate + octan-1-ol

Left to rightBalancedRhea 59108

L-serine + ATP = O-phospho-L-serine + ADP + H(+)

Direction not assertedBalancedRhea 59112

[protein]-dithiol + O2 = [protein]-disulfide + H2O2

Left to rightBalance undeterminableRhea 59116

2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H(+) = 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO2

Direction not assertedBalancedRhea 59120

(S)-2,3-diaminopropanoate + citrate + ATP = 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate

Direction not assertedBalancedRhea 59124

2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + (S)-2,3-diaminopropanoate + ATP = 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + AMP + diphosphate

Direction not assertedBalancedRhea 59128

2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP = staphyloferrin B + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 59132

D-ornithine + citrate + ATP = N(5)-[(S)-citryl]-D-ornithine + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 59136

N(5)-[(S)-citryl]-D-ornithine + citrate + ATP = staphyloferrin A + AMP + diphosphate + H(+)

Direction not assertedBalancedRhea 59140

10-formyldihydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 7,8-dihydrofolate

Left to rightBalancedRhea 59144

marinolate C + ATP + CoA = marinoloyl-CoA C + AMP + diphosphate

Direction not assertedBalancedRhea 59148

pseudomonate C + ATP + CoA = pseudomonoyl-CoA C + AMP + diphosphate

Direction not assertedBalancedRhea 59152

eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP = icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 59156

holo-[(phenol)carboxyphthiodiolenone synthase] + docosanoate + ATP = docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 59160

holo-[(hydroxy)phthioceranic acid synthase] + hexadecanoate + ATP = hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 59164

holo-[(hydroxy)phthioceranic acid synthase] + octadecanoate + ATP = octadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 59168

hexadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] = hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59172

L-serine + ADP = O-phospho-L-serine + AMP + H(+)

Direction not assertedBalancedRhea 59176

5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP + H(+)

Direction not assertedBalancedRhea 59180

2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate

Direction not assertedBalancedRhea 59184

L-histidine = D-histidine

Direction not assertedBalancedRhea 59188

eicosanoate + ATP + H(+) = icosanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 59192

icosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59196

docosanoate + ATP + H(+) = docosanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 59200

docosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59204

octadecanoate + ATP + H(+) = octadecanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 59208

octadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] = octadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 59212

(indol-3-yl)acetate + H(+) = skatole + CO2

Direction not assertedBalancedRhea 59216

(2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + acetate + H(+)

Direction not assertedBalancedRhea 59220

(2E,6E,10E)-geranylgeranyl diphosphate = hydropyrene + diphosphate

Direction not assertedBalancedRhea 59224

6-sulfo-alpha-D-quinovose = 6-sulfo-beta-D-quinovose

Direction not assertedBalancedRhea 59228

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = hydropyrenol + diphosphate

Direction not assertedBalancedRhea 59232

(2E,6E,10E)-geranylgeranyl diphosphate = isoelisabethatriene + diphosphate

Direction not assertedBalancedRhea 59236

L-lysine + L-arginine = L-homoarginine + L-ornithine

Direction not assertedBalancedRhea 59240

3''-O-acetyl-ADP-D-ribose + H2O = ADP-D-ribose + acetate + H(+)

Left to rightBalancedRhea 59244

(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + (E)-4-coumaroyl-CoA = (R)-3-(4-hydroxyphenyl)lactoyl-CoA + (E)-4-coumarate

Direction not assertedBalancedRhea 59248

(R)-3-(indol-3-yl)lactate + (E)-3-(indol-3-yl)acryloyl-CoA = (R)-3-(indol-3-yl)lactoyl-CoA + (E)-3-(indol-3-yl)acrylate

Direction not assertedBalancedRhea 59252

Fe(III)-enterobactin + H2O = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H(+)

Direction not assertedBalancedRhea 59256

Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H2O + H(+) = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine

Direction not assertedBalancedRhea 59260

Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H2O + H(+) = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine

Direction not assertedBalancedRhea 59264

N(6)-methyl-L-lysyl-[protein] + A + H2O = L-lysyl-[protein] + formaldehyde + AH2

Direction not assertedBalance undeterminableRhea 59268

L-cysteine = D-cysteine

Direction not assertedBalancedRhea 59272

L-glutamine = D-glutamine

Direction not assertedBalancedRhea 59276

L-asparagine = D-asparagine

Direction not assertedBalancedRhea 59280

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