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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,651–11,700 of 18,558 reactions from Rhea

alpha-N-dichloroacetyl-p-aminophenylserinol + AH2 + 2 O2 = chloramphenicol + A + 2 H2O
Direction not assertedBalancedRhea 58884
4-aminobenzoate + AH2 + 2 O2 = 4-nitrobenzoate + A + 2 H2O
Direction not assertedBalancedRhea 58888
omega-hydroxy-beta-dihydromenaquinone-9 + 3'-phosphoadenylyl sulfate = omega-sulfo-beta-dihydromenaquinone-9 + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 58892
4-hydroxybutanoate + ATP + CoA = 4-hydroxybutanoyl-CoA + ADP + phosphate
Direction not assertedBalancedRhea 58896
1-carboxybiuret + H2O = urea-1,3-dicarboxylate + NH4(+)
Direction not assertedBalancedRhea 58900
hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 8 (S)-methylmalonyl-CoA + 16 NADPH + 24 H(+) = C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 8 CO2 + 16 NADP(+) + 8 CoA + 8 H2O
Direction not assertedBalance undeterminable

Rhea 58904

hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 7 (S)-methylmalonyl-CoA + 14 NADPH + 21 H(+) = C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 7 CO2 + 14 NADP(+) + 7 CoA + 7 H2O

Direction not assertedBalance undeterminableRhea 58908

iron(III) dicitrate(out) + ATP + H2O = iron(III) dicitrate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 58912

squalene + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 58916

(3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol = (+)-medicarpin + H2O

Direction not assertedBalancedRhea 58920

(3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol = (-)-maackiain + H2O

Direction not assertedBalancedRhea 58924

(3R,4R)-7,2',4'-trihydroxyisoflavanol = (6aR,11aR)-3,9-dihydroxypterocarpan + H2O

Direction not assertedBalancedRhea 58928

4-nitrobenzoyl-CoA + 4 (S)-methylmalonyl-CoA + malonyl-CoA + 4 NADPH + 8 H(+) = demethylluteothin + 5 CO2 + 4 NADP(+) + 6 CoA + 3 H2O

Direction not assertedBalancedRhea 58932

2 (2E,6E,10E)-geranylgeranyl diphosphate + NADH + H(+) = all-trans-lycopaoctaene + 2 diphosphate + NAD(+)

Direction not assertedBalancedRhea 58936

(1R,2R,3R)-prephytoene diphosphate + NADH + H(+) = all-trans-lycopaoctaene + diphosphate + NAD(+)

Direction not assertedBalancedRhea 58940

4-nitrobenzoyl-CoA + 6 (S)-methylmalonyl-CoA + malonyl-CoA + 6 NADPH + 12 H(+) = demethyldeoxyspectinabilin + 7 CO2 + 6 NADP(+) + 8 CoA + 5 H2O

Direction not assertedBalancedRhea 58944

4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP + n H(+)

Direction not assertedBalance undeterminableRhea 58948

(20S)-protopanaxatriol + UDP-alpha-D-glucose = (20S)-ginsenoside Rh1 + UDP + H(+)

Direction not assertedBalancedRhea 58952

a ribonucleotide in RNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in RNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 58956

benzaldehyde + O2 + H2O = benzoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58960

hexanal + O2 + H2O = hexanoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58964

1-naphthaldehyde + O2 + H2O = 1-naphthoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58968

vanillin + O2 + H2O = vanillate + H2O2 + H(+)

Direction not assertedBalancedRhea 58972

malonaldehyde + O2 + H2O = 3-oxopropanoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58976

citral + O2 + H2O = 3,7-dimethylocta-2,6-dienoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58980

acrolein + O2 + H2O = acrylate + H2O2 + H(+)

Direction not assertedBalancedRhea 58984

(E)-4-hydroxynon-2-enal + O2 + H2O = (E)-4-hydroxynon-2-enoate + H2O2 + H(+)

Direction not assertedBalancedRhea 58988

(E)-cinnamaldehyde + O2 + H2O = (E)-cinnamate + H2O2 + H(+)

Direction not assertedBalancedRhea 58992

indole-3-carbaldehyde + O2 + H2O = indole-3-carboxylate + H2O2 + H(+)

Direction not assertedBalancedRhea 58996

propanal + O2 + H2O = propanoate + H2O2 + H(+)

Direction not assertedBalancedRhea 59000

dodecanal + O2 + H2O = dodecanoate + H2O2 + H(+)

Direction not assertedBalancedRhea 59004

salicylaldehyde + O2 + H2O = salicylate + H2O2 + H(+)

Direction not assertedBalancedRhea 59008

cycloartenol + S-adenosyl-L-methionine = 24-methylenecycloartanol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 59012

4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+) = cycloeucalenone + CO2 + NADH

Direction not assertedBalancedRhea 59016

1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O = di-(9Z,12Z)-octadecadienoylglycerol + (9Z,12Z)-octadecadienoate + H(+)

Direction not assertedBalancedRhea 59020

trihexadecanoylglycerol + H2O = dihexadecanoylglycerol + hexadecanoate + H(+)

Left to rightBalancedRhea 59024

(Z)-24-ethylidenelophenol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Direction not assertedBalance undeterminableRhea 59028

(Z)-24-ethylidenelophenol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 59032

4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 59036

4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 59040

dammarenediol-II + UDP-alpha-D-glucose = (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + UDP + H(+)

Direction not assertedBalancedRhea 59044

D-ornithine + H(+) = putrescine + CO2

Direction not assertedBalancedRhea 59048

D-lysine + H(+) = cadaverine + CO2

Direction not assertedBalancedRhea 59052

2 methanethiol + NAD(+) = dimethyl disulfide + NADH + H(+)

Direction not assertedBalancedRhea 59056

(20S)-ginsenoside Rg3 + H2O = (20S)-ginsenoside Rh2 + D-glucose

Direction not assertedBalancedRhea 59060

demethylluteothin + S-adenosyl-L-methionine = luteothin + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 59064

demethyldeoxyspectinabilin + S-adenosyl-L-methionine = deoxyspectinabilin + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 59068

cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + AH2 + 2 S-adenosyl-L-methionine = cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 59072

bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose = 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+)

Direction not assertedBalancedRhea 59076

bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose = 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)

Direction not assertedBalancedRhea 59080

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