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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Proteins
Interactions
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Reactions
Reach

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Cell types
Organisms
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,101–1,150 of 18,558 reactions from Rhea

[(1->6)-alpha-D-glucosyl](n+1) + [(1->4)-alpha-D-glucosyl](n) = [(1->6)-alpha-D-glucosyl](n) + [(1->4)-alpha-D-glucosyl](n+1)
Direction not assertedBalance undeterminableRhea 14625
N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP
Direction not assertedBalancedRhea 14629
Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 14633
a thiol + 3'-phosphoadenylyl sulfate = S-alkyl thiosulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalance undeterminableRhea 14637
cyanurate + H2O = biuret + CO2
Direction not assertedBalancedRhea 14641
dTDP-beta-L-mycarose + demethyllactenocin = demethylmacrocin + dTDP + H(+)
Direction not assertedBalancedRhea 14649
a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate + H(+)

Left to rightBalance undeterminableRhea 14653

aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate

ReversibleBalancedRhea 14657

guanine + H2O + H(+) = xanthine + NH4(+)

Left to rightBalancedRhea 14665

D-glyceraldehyde 3-phosphate + NADP(+) + H2O = (2R)-3-phosphoglycerate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 14669

a polar amino acid(out) + ATP + H2O = a polar amino acid(in) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableTransportRhea 14673

2 2-aminophenol + A + O2 = 2-aminophenoxazin-3-one + AH2 + 2 H2O

Direction not assertedBalancedRhea 14681

a primary alcohol + A = an aldehyde + AH2

Direction not assertedBalance undeterminableRhea 14685

4-chlorophenylacetate + NADH + O2 = 3,4-dihydroxyphenylacetate + chloride + NAD(+)

Direction not assertedBalancedRhea 14689

a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-phospho-di-trans,poly-cis-dolichol + UDP

Direction not assertedBalance undeterminableRhea 14693

(2E,6E)-farnesol + NADP(+) = (2E,6E)-farnesal + NADPH + H(+)

Direction not assertedBalancedRhea 14697

NAD(+) + 2 CoA = CoA-disulfide + NADH + H(+)

Direction not assertedBalancedRhea 14701

NADP(+) + 2 CoA = CoA-disulfide + NADPH + H(+)

Direction not assertedBalancedRhea 14705

a 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid

Direction not assertedBalance undeterminableRhea 14709

keto-L-sorbose + A = 5-dehydro-D-fructose + AH2

Direction not assertedBalancedRhea 14713

D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate

Direction not assertedBalancedRhea 14717

zeatin + UDP-alpha-D-xylose = O-beta-D-xylosylzeatin + UDP + H(+)

Direction not assertedBalancedRhea 14721

2 cob(II)inamide + reduced [electron-transfer flavoprotein] + 2 ATP = 2 adenosylcob(III)inamide + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 14725

beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate

ReversibleBalancedRhea 14729

Ag(+)(in) + ATP + H2O = Ag(+)(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 14733

CTP = 3',5'-cyclic CMP + diphosphate

Direction not assertedBalancedRhea 14737

4-methylene-L-glutamine + H2O = 4-methylene-L-glutamate + NH4(+)

Direction not assertedBalancedRhea 14741

1-hydroxy-2-naphthoate + O2 = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(+)

Direction not assertedBalancedRhea 14749

17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = androst-4-ene-3,17-dione + acetate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 14753

L-galactono-1,4-lactone + 2 Fe(III)-[cytochrome c] = L-ascorbate + 2 Fe(II)-[cytochrome c] + 3 H(+)

Direction not assertedBalance undeterminableRhea 14757

L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA

Left to rightBalancedRhea 14761

coelenterazine h + O2 = excited coelenteramide h monoanion + hnu + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 14765

(S)-nicotine + A + H2O = (S)-6-hydroxynicotine + AH2

Direction not assertedBalancedRhea 14769

palmatine + S-adenosyl-L-methionine + 2 NADPH = corydaline + S-adenosyl-L-homocysteine + 2 NADP(+)

Direction not assertedBalancedRhea 14773

AMP + H2O + H(+) = IMP + NH4(+)

Left to rightBalancedRhea 14777

heptanedioate + ATP + CoA = 6-carboxyhexanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 14781

RNA(n) + UTP = RNA(n)-3'-uridine ribonucleotide + diphosphate

Direction not assertedBalance undeterminableRhea 14785

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)

Left to rightBalance undeterminableRhea 14789

2-hydroxyadipate + NAD(+) = 2-oxoadipate + NADH + H(+)

Direction not assertedBalancedRhea 14793

2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)

Direction not assertedBalancedRhea 14797

(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP

ReversibleBalancedRhea 14801

D-allose + ATP = D-allose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 14805

phenol + S-adenosyl-L-methionine = anisole + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 14809

L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam

Direction not assertedBalancedRhea 14813

4-maleylacetoacetate = 4-fumarylacetoacetate

Direction not assertedBalancedRhea 14817

beta-L-arabinopyranose = L-ribulose

Direction not assertedBalancedRhea 14821

(1R,5S)-carveol + NAD(+) = (S)-carvone + NADH + H(+)

Direction not assertedBalancedRhea 14825

O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate

Direction not assertedBalancedRhea 14829

(R)-mevalonate + 2 NAD(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H(+)

Direction not assertedBalancedRhea 14833

glyoxylate + O2 + H2O = oxalate + H2O2 + H(+)

Left to rightBalancedRhea 14837

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