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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,401–11,450 of 18,558 reactions from Rhea

a pyrimidine 2'-deoxyribonucleoside 5'-phosphate + H2O = a pyrimidine nucleobase + 2-deoxy-D-ribose 5-phosphate
Direction not assertedBalance undeterminableRhea 57852
(E)-feruloyl-CoA + 2-oxoglutarate + O2 = (E)-6-hydroxyferuloyl-CoA + succinate + CO2
Direction not assertedBalancedRhea 57856
(E)-6-hydroxyferuloyl-CoA = scopoletin + CoA
Direction not assertedBalancedRhea 57860
indole-3-carbonyl nitrile + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxy-indole-3-carbonyl nitrile + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 57864
(E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-CoA + succinate + CO2
Direction not assertedBalancedRhea 57868
(E)-2,4-dihydroxycinnamoyl-CoA = umbelliferone + CoA
Direction not assertedBalancedRhea 57872

uridine(54) in tRNA = pseudouridine(54) in tRNA

Left to rightBalancedRhea 57876

3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose = 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 57880

Na(+)(in) + diphosphate + H2O = Na(+)(out) + 2 phosphate + H(+)

Direction not assertedBalancedTransportRhea 57884

a quinone + NADH + 5 H(+)(in) = a quinol + NAD(+) + 4 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 57888

a quinone + NADPH + 5 H(+)(in) = a quinol + NADP(+) + 4 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 57892

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + 2-oxoglutarate + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 57896

N(6)-methyladenosine in U6 snRNA + 2-oxoglutarate + O2 = adenosine in U6 snRNA + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 57900

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in U6 snRNA + 2-oxoglutarate + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in U6 snRNA + formaldehyde + succinate + CO2

Direction not assertedBalance undeterminableRhea 57904

L-glutamyl-tRNA(Gln) + ATP = 5-phosphooxy-L-glutamyl-tRNA(Gln) + ADP

Direction not assertedBalancedRhea 57908

5-phosphooxy-L-glutamyl-tRNA(Gln) + NH4(+) = L-glutaminyl-tRNA(Gln) + phosphate + H(+)

Direction not assertedBalancedRhea 57912

L-aspartyl-tRNA(Asn) + ATP = 4-phosphooxy-L-aspartyl-tRNA(Asn) + ADP + H(+)

Direction not assertedBalancedRhea 57916

4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+) = L-asparaginyl-tRNA(Asn) + phosphate + H(+)

Direction not assertedBalancedRhea 57920

mutildienyl diphosphate + H2O = premutilin + diphosphate

Direction not assertedBalancedRhea 57924

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + L-glutamine + ATP + H2O = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 57928

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+) = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + phosphate + H(+)

Direction not assertedBalancedRhea 57932

isopyridoxal + NAD(+) + H2O = 5-pyridoxate + NADH + 2 H(+)

Direction not assertedBalancedRhea 57936

Fe-coproporphyrin III + H2O2 + H(+) = harderoheme III + CO2 + 2 H2O

Direction not assertedBalancedRhea 57940

harderoheme III + H2O2 + H(+) = heme b + CO2 + 2 H2O

Direction not assertedBalancedRhea 57944

2-hydroxytoluene + NADH + O2 + H(+) = 3-methylcatechol + NAD(+) + H2O

Direction not assertedBalancedRhea 57948

phenol + NADH + O2 + H(+) = catechol + NAD(+) + H2O

Direction not assertedBalancedRhea 57952

dimethyl sulfoxide + NADH + O2 + H(+) = dimethyl sulfone + NAD(+) + H2O

Direction not assertedBalancedRhea 57956

dimethyl sulfide + NADH + O2 + H(+) = dimethyl sulfoxide + NAD(+) + H2O

Direction not assertedBalancedRhea 57960

germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57964

germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = 8-epi-inunolide + oxidized [NADPH--hemoprotein reductase] + 2 H2O

Direction not assertedBalance undeterminableRhea 57968

8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = eupatolide + oxidized [NADPH--hemoprotein reductase] + 2 H2O

Direction not assertedBalance undeterminableRhea 57972

(20S)-protopanaxadiol + UDP-alpha-D-glucose = (20S)-ginsenoside C-K + UDP + H(+)

Direction not assertedBalancedRhea 57976

(20S)-protopanaxatriol + UDP-alpha-D-glucose = (20S)-ginsenoside F1 + UDP + H(+)

Direction not assertedBalancedRhea 57980

(20S)-ginsenoside Rg3 + UDP-alpha-D-glucose = (20S)-ginsenoside Rd + UDP + H(+)

Direction not assertedBalancedRhea 57984

(20S)-ginsenoside Rh2 + UDP-alpha-D-glucose = (20S)-ginsenoside F2 + UDP + H(+)

Direction not assertedBalancedRhea 57988

(20S)-ginsenoside C-K + UDP-alpha-D-glucose = (20S)-ginsenoside F2 + UDP + H(+)

Direction not assertedBalancedRhea 57992

(20S)-protopanaxadiol + UDP-alpha-D-glucose = (20S)-ginsenoside Rh2 + UDP + H(+)

Direction not assertedBalancedRhea 57996

(20S)-ginsenoside Rh2 + UDP-alpha-D-glucose = (20S)-ginsenoside Rg3 + UDP + H(+)

Direction not assertedBalancedRhea 58000

(20S)-ginsenoside F2 + UDP-alpha-D-glucose = (20S)-ginsenoside Rd + UDP + H(+)

Direction not assertedBalancedRhea 58004

(20S)-ginsenoside F1 + UDP-alpha-D-glucose = (20S)-ginsenoside Rg1 + UDP + H(+)

Direction not assertedBalancedRhea 58008

cyclic tetraadenylate = 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate

Direction not assertedBalancedRhea 58012

8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 58016

6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = eupatolide + H2O

Direction not assertedBalancedRhea 58020

oleanolate + UDP-alpha-D-glucose = oleanolate 3-O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 58024

a medium-chain fatty acyl-CoA + 5 (S)-methylmalonyl-CoA + 5 malonyl-CoA + 22 NADPH + 32 H(+) = a mycoketide-CoA + 10 CO2 + 22 NADP(+) + 10 CoA + 11 H2O

Direction not assertedBalance undeterminableRhea 58028

germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 58032

8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = 8-epi-inunolide + H2O

Direction not assertedBalancedRhea 58036

1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + H2O = (9Z,12Z,15Z)-octadecatrienoate + glycerol + H(+)

Direction not assertedBalancedRhea 58040

a long-chain fatty acyl-CoA + alpha,alpha-trehalose = a 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA

Direction not assertedBalance undeterminableRhea 58044

2-O-sulfo-alpha,alpha-trehalose + octadecanoyl-CoA = 2-O-sulfo-2'-O-octadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 58048

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