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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,301–11,350 of 18,558 reactions from Rhea

2-methylanisole + reduced [NADH--hemoprotein reductase] + O2 = 2-hydroxytoluene + oxidized [NADH--hemoprotein reductase] + formaldehyde + H2O + H(+)
Direction not assertedBalance undeterminableRhea 57440
C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine
Left to rightBalance undeterminableRhea 57444
D-tyrosine + tRNA(Tyr) + ATP = D-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)
Direction not assertedBalancedRhea 57448
L-glutaminyl-[protein] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine + H(+)
Left to rightBalance undeterminableRhea 57452
(E)-sinapate + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-sinapate + UDP + H(+)
Direction not assertedBalancedRhea 57456
(E)-sinapyl alcohol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol + UDP + H(+)
Direction not asserted

Balanced

Rhea 57460

(E)-caffeate + UDP-alpha-D-glucose = 1-O-[(E)-caffeoyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57464

(E)-ferulate + UDP-alpha-D-glucose = 1-O-[(E)-feruloyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57468

(E)-4-coumarate + UDP-alpha-D-glucose = 1-O-[(E)-4-coumaroyl]-beta-D-glucose + UDP

Direction not assertedBalancedRhea 57472

dodecanoate + H2O2 = 2-hydroxydodecanoate + H2O

Direction not assertedBalancedRhea 57476

2-hydroxydodecanoate + H2O2 = 2,3-dihydroxydodecanoate + H2O

Direction not assertedBalancedRhea 57480

2 nitrite + AH2 + 2 H(+) = 2 nitric oxide + A + 2 H2O

Left to rightBalancedRhea 57488

propanoyl-CoA + oxaloacetate + H2O = 2-methylcitrate + CoA + H(+)

Direction not assertedBalancedRhea 57492

2-methylcitrate = 2-methyl-cis-aconitate + H2O

Direction not assertedBalancedRhea 57496

3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O

Direction not assertedBalancedRhea 57500

3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate

Direction not assertedBalancedRhea 57504

staphylopine + NADP(+) + H2O = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H(+)

Direction not assertedBalancedRhea 57508

chlorobenzene + NADH + O2 + H(+) = (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+)

Direction not assertedBalancedRhea 57512

dolabradiene + reduced [NADPH--hemoprotein reductase] + O2 = 15,16-epoxydolabrene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57516

15,16-epoxydolabrene + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxy-15,16-epoxydolabrene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57520

a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57524

a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O = a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57528

a 5'-end ribonucleotide-RNA + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + diphosphate

Direction not assertedBalance undeterminableRhea 57532

a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate = a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)

Direction not assertedBalance undeterminableRhea 57536

a 5'-end NTP-ribonucleotide-RNA + H2O = a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 57540

(S)-beta-macrocarpene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = zealexin A1 + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 57544

(S)-beta-macrocarpene + reduced [NADPH--hemoprotein reductase] + O2 = [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57548

[(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + reduced [NADPH--hemoprotein reductase] + O2 = (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 57552

(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + reduced [NADPH--hemoprotein reductase] + O2 = zealexin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 57556

(+)-cis-trans-nepetalactol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 7-deoxyloganetate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 57560

(+)-cis-trans-nepetalactol + reduced [NADPH--hemoprotein reductase] + O2 = 7-deoxyloganetic alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57564

7-deoxyloganetic alcohol + reduced [NADPH--hemoprotein reductase] + O2 = 7-deoxyloganetic aldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 57568

7-deoxyloganetic aldehyde + reduced [NADPH--hemoprotein reductase] + O2 = 7-deoxyloganetate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 57572

7-deoxyloganate + reduced [NADPH--hemoprotein reductase] + O2 = loganate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57576

5-(methylsulfanyl)-D-ribulose 1-phosphate = 1-(methylsulfanyl)ribulose 5-phosphate

Direction not assertedBalancedRhea 57580

a flavanone + reduced [NADPH--hemoprotein reductase] + O2 = a 2-hydroxyflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57584

(2S)-naringenin + reduced [NADPH--hemoprotein reductase] + O2 = (2S)-2-hydroxynaringenin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57588

(S)-pinocembrin + reduced [NADPH--hemoprotein reductase] + O2 = (2S)-2-hydroxypinocembrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57592

(S)-eriodictyol + reduced [NADPH--hemoprotein reductase] + O2 = (2S)-2-hydroxyeriodictyol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57596

a 1-hexacosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-[(17Z)-hexacos-17-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 57600

a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 57604

(1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+) = 3-chlorocatechol + NADH + H(+)

Direction not assertedBalancedRhea 57608

holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + 20 H(+) = dihydro-ML-236C-[compactin nonaketide synthase] + 9 CO2 + 11 NADP(+) + 9 CoA + 6 H2O

Direction not assertedBalance undeterminableRhea 57612

dihydro-ML-236C-[compactin nonaketide synthase] + H2O = holo-[compactin nonaketide synthase] + dihydro-ML-236C carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 57616

dihydro-ML-236C carboxylate + reduced [NADPH--hemoprotein reductase] + O2 = ML-236C carboxylate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 57620

dihydro-ML-236C carboxylate + reduced [NADPH--hemoprotein reductase] + O2 = 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57624

3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate = ML-236C carboxylate + H2O

Direction not assertedBalancedRhea 57628

ML-236C carboxylate + reduced [NADPH--hemoprotein reductase] + O2 = ML-236A carboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 57632

ML-236A carboxylate + (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] = mevinic carboxylate + holo-[2-methylbutanoate polyketide synthase]

Direction not assertedBalance undeterminableRhea 57636

trichosetin + S-adenosyl-L-methionine = equisetin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 57648

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