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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

11,101–11,150 of 18,558 reactions from Rhea

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoate + H(+)
Direction not assertedBalancedRhea 56640
a uridine in mRNA = a pseudouridine in mRNA
Left to rightBalance undeterminableRhea 56644
3-oxochol-4-en-24-oyl-CoA + NAD(+) = 3-oxochol-4,6-dien-24-oyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 56648
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 56652
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 56656
7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea

56660

7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56664

7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 56668

dihydro-4-coumaroyl-CoA + NADP(+) = (E)-4-coumaroyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 56672

dihydroferuloyl-CoA + NADP(+) = (E)-feruloyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 56676

beta-dihydromenaquinone-9 + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 56680

dihydrorhizobitoxine + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = rhizobitoxine + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 56684

(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + succinate + CO2 + H2O

Direction not assertedBalancedRhea 56688

(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 4-[(E)-2-isocyanoethenyl]phenol + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56692

D-ribulose 5-phosphate + L-tryptophan = (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + hydroxyacetone + formaldehyde + phosphate + H2O + H(+)

Direction not assertedBalancedRhea 56696

(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56700

(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 3-[(E)-2-isocyanovinyl]indole + succinate + 2 CO2 + H2O

Direction not assertedBalancedRhea 56704

beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 56708

L-cysteinyl-[prolipoprotein] + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = an S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 56712

S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + H2O = S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 56716

L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 56720

all-trans-beta-carotene + AH2 + O2 = 4-hydroxy-all-trans-beta-carotene + A + H2O

Direction not assertedBalancedRhea 56724

4-hydroxy-all-trans-beta-carotene + AH2 + O2 = 4,4-dihydroxy-all-trans-beta-carotene + A + H2O

Direction not assertedBalancedRhea 56728

4,4-dihydroxy-all-trans-beta-carotene = echinenone + H2O

Direction not assertedBalancedRhea 56732

retinal + O2 + H2O = retinoate + H2O2 + H(+)

Direction not assertedBalancedRhea 56736

a globoside Gb3Cer + UDP-alpha-D-galactose = a globoside GalGb3Cer + UDP + H(+)

Left to rightBalance undeterminableRhea 56740

L-arginyl-[protein] + 2-oxoglutarate + O2 = (3R)-3-hydroxy-L-arginyl-[protein] + succinate + CO2

Direction not assertedBalance undeterminableRhea 56744

an omega-methyl-long-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-hydroxy-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 56748

a 14alpha-methyl steroid + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = a Delta(14) steroid + formate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 56752

obtusifoliol + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 56756

24,25-dihydrolanosterol + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 56760

12-epi-fischerindole U + chloride + 2-oxoglutarate + O2 + H(+) = 12-epi-fischerindole G + succinate + CO2 + H2O

Direction not assertedBalancedRhea 56764

all-trans-zeaxanthin + 2 AH2 + 2 O2 = all-trans-adonixanthin + 2 A + 3 H2O

Direction not assertedBalancedRhea 56768

all-trans-adonixanthin + 2 AH2 + 2 O2 = all-trans-(3S,3'S)-astaxanthin + 2 A + 3 H2O

Direction not assertedBalancedRhea 56772

(+)-pinoresinol + reduced [NADPH--hemoprotein reductase] + O2 = (+)-piperitol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 56776

(+)-piperitol + reduced [NADPH--hemoprotein reductase] + O2 = (+)-sesamin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 56780

(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate

Left to rightBalance undeterminableRhea 56784

apo-[corrinoid adenosyltransferase] + cob(II)alamin = cob(II)alamin-[corrinoid adenosyltransferase]

Direction not assertedBalance undeterminableRhea 56788

2 cob(II)alamin-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] = 2 cob(I)alamin-[corrinoid adenosyltransferase] + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 56792

cob(I)alamin-[corrinoid adenosyltransferase] + ATP = apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate

Left to rightBalance undeterminableRhea 56796

cob(II)yrinate a,c diamide + apo-[corrinoid adenosyltransferase] = cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase]

Direction not assertedBalance undeterminableRhea 56800

2 cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] = 2 cob(I)yrinate a,c diamide-[corrinoid adenosyltransferase] + oxidized [electron-transfer flavoprotein] + 3 H(+)

Direction not assertedBalance undeterminableRhea 56804

cob(I)yrinate a,c diamide-[corrinoid adenosyltransferase] + ATP = adenosylcob(III)yrinate a,c-diamide + apo-[corrinoid adenosyltransferase] + triphosphate

Direction not assertedBalance undeterminableRhea 56808

L-threonyl-[peptidyl-carrier protein] + chloride + 2-oxoglutarate + O2 + H(+) = 4-chloro-L-threonyl-[peptidyl-carrier protein] + succinate + CO2 + H2O

Direction not assertedBalance undeterminableRhea 56812

a pyrimidine ribonucleoside + H2O = a pyrimidine nucleobase + D-ribose

Direction not assertedBalance undeterminableRhea 56816

cyclooctat-9-en-7-ol + AH2 + O2 = cyclooctat-9-ene-5,7-diol + A + H2O

Direction not assertedBalancedRhea 56820

cyclooctat-9-ene-5,7-diol + AH2 + O2 = cyclooctatin + A + H2O

Direction not assertedBalancedRhea 56824

2,3,6-trichlorohydroquinone + glutathione disulfide + chloride = 2,3,5,6-tetrachlorohydroquinone + 2 glutathione

Direction not assertedBalancedRhea 56828

2,6-dichlorohydroquinone + glutathione disulfide + chloride + H(+) = 2,3,6-trichlorohydroquinone + 2 glutathione

Direction not assertedBalancedRhea 56832

[PQQ precursor protein] + S-adenosyl-L-methionine = E-Y cross-linked-[PQQ precursor protein] + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalance undeterminableRhea 56836

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