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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,851–10,900 of 18,558 reactions from Rhea

a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol phosphomannosylnositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol
Direction not assertedBalance undeterminableRhea 55608
an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + H2O = 1-methyladenine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + H(+)
Direction not assertedBalance undeterminableRhea 55612
a carotenoid psi-end derivative = a carotenoid epsilon-end derivative
Direction not assertedBalance undeterminableRhea 55616
a carotenoid psi-end derivative = a carotenoid beta-end derivative
Direction not assertedBalance undeterminableRhea 55620
an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O = 3-methylcytosine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + H(+)
Direction not assertedBalance undeterminableRhea 55624
1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)

Left to rightBalancedRhea 55632

C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + ATP + H2O = C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + AMP + phosphate + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 55636

C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate = C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55640

C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + ATP = C-terminal S-cyanate-L-cysteinyl-[HypE protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 55644

validoxylamine A + 2-oxoglutarate + O2 = validoxylamine B + succinate + CO2 + H(+)

Direction not assertedBalancedRhea 55648

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate

Left to rightBalance undeterminableRhea 55652

a carotenoid beta-end derivative + 2 A = a carotenoid chi-end derivative + 2 AH2

Direction not assertedBalance undeterminableRhea 55656

all-trans-beta-carotene + 2 AH2 + 2 O2 = echinenone + 2 A + 3 H2O

Direction not assertedBalancedRhea 55660

echinenone + 2 AH2 + 2 O2 = canthaxanthin + 2 A + 3 H2O

Direction not assertedBalancedRhea 55664

11-cis-retinol--[retinol-binding protein] + NAD(+) = 11-cis-retinal--[retinol-binding protein] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 55668

4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP + n H(+)

Direction not assertedBalance undeterminableRhea 55672

chorismate + NH4(+) = (2S)-2-amino-4-deoxychorismate + H2O

Direction not assertedBalancedRhea 55676

(2S)-2-amino-4-deoxychorismate = anthranilate + pyruvate + H(+)

Direction not assertedBalancedRhea 55680

chorismate + NH4(+) = 4-amino-4-deoxychorismate + H2O

Direction not assertedBalancedRhea 55684

an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + H2O = 1D-myo-inositol 1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)

Direction not assertedBalance undeterminableRhea 55688

an inositol-1-phosphoceramide + H2O = 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)

Direction not assertedBalance undeterminableRhea 55692

a mannosylinositol-1-phospho-N-acyl-sphingoid base + H2O = mannosylinositol-1-phosphate + an N-acyl-sphingoid base + H(+)

Direction not assertedBalance undeterminableRhea 55696

an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O = mannosyldiinositol-1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+)

Direction not assertedBalance undeterminableRhea 55700

hydrogen sulfide + glycine + NAD(+) = ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + H(+)

Direction not assertedBalancedRhea 55704

[ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) = [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 55708

3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55712

(S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O = (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55716

17-(4-hydroxyphenyl)heptadecanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 55720

17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55724

19-(4-hydroxyphenyl)nonadecanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 55728

19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55732

alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose = [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 55736

oleuropein + H2O = oleuropein aglycone + D-glucose

Direction not assertedBalancedRhea 55740

coenzyme B + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 4 H(+) = coenzyme M-coenzyme B heterodisulfide + 2 reduced coenzyme F420-(gamma-L-Glu)(n) + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55744

coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55748

coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin]

Direction not assertedBalance undeterminableRhea 55752

an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + 2-oxoglutarate + O2 = a 2-hydroxyornithine lipid + succinate + CO2

Direction not assertedBalance undeterminableRhea 55756

a lyso-ornithine lipid + a fatty acyl-[ACP] = an N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine lipid + holo-[ACP]

Direction not assertedBalance undeterminableRhea 55760

1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O = 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol

Direction not assertedBalancedRhea 55764

all-trans-retinoate + UDP-alpha-D-glucuronate = all-trans-retinoyl-1-O-(beta-D-glucuronate) + UDP

Left to rightBalancedRhea 55768

a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 55772

all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + UDP + H(+)

Left to rightBalancedRhea 55776

all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate = all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP

Direction not assertedBalancedRhea 55780

all-trans-4-oxoretinoate + UDP-alpha-D-glucuronate = all-trans-4-oxoretinoate 1-O-(beta-D-glucuronate) + UDP

Direction not assertedBalancedRhea 55784

acetone + NADH + O2 + H(+) = hydroxyacetone + NAD(+) + H2O

Direction not assertedBalancedRhea 55788

butan-2-one + NADH + O2 + H(+) = 1-hydroxy-2-butanone + NAD(+) + H2O

Direction not assertedBalancedRhea 55792

phenol + NADH + O2 + H(+) = hydroquinone + NAD(+) + H2O

Direction not assertedBalancedRhea 55796

an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acyleicosasphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 55800

(R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O = (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55804

a dihydroceramide + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 55808

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