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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,001–1,050 of 18,558 reactions from Rhea

D-lyxose = D-xylulose
Direction not assertedBalancedRhea 14201
carnosine + S-adenosyl-L-methionine = anserine + S-adenosyl-L-homocysteine + H(+)
Left to rightBalancedRhea 14205
alpha-D-galactose 1-phosphate + UTP + H(+) = UDP-alpha-D-galactose + diphosphate
Direction not assertedBalancedRhea 14209
beta-D-fructose 1-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)
Direction not assertedBalancedRhea 14213
L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol
Direction not assertedBalance undeterminableRhea 14217
monomethyl sulfate + H2O = methanol + sulfate + H(+)
Direction not assertedBalancedRhea 14221
6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + NADH + H(+)

Direction not assertedBalancedRhea 14225

(6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 14229

a 2-acyl-sn-glycerol 3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA

Direction not assertedBalance undeterminableRhea 14233

10-deoxysarpagine + reduced [NADPH--hemoprotein reductase] + O2 = sarpagine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 14237

3-amino-4-hydroxybenzaldehyde + acetyl-CoA = 3-acetylamino-4-hydroxybenzaldehyde + CoA + H(+)

Direction not assertedBalancedRhea 14241

ATP + H2O = AMP + diphosphate + H(+)

Left to rightBalancedRhea 14245

guanosine 3',5'-bis(diphosphate) + H2O = GDP + diphosphate + H(+)

Direction not assertedBalancedRhea 14253

a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+)

Left to rightBalance undeterminableRhea 14257

(E)-sinapoyl-CoA + D-glucono-1,5-lactone = 6-O-[(E)-sinapoyl]-D-glucono-1,5-lactone + CoA

Direction not assertedBalancedRhea 14261

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate

Direction not assertedBalancedRhea 14265

2 a quinone + NADPH + H(+) = 2 a 1,4-benzosemiquinone + NADP(+)

Left to rightBalance undeterminableRhea 14269

spermidine + A + H2O = 4-aminobutanal + propane-1,3-diamine + AH2

Direction not assertedBalancedRhea 14273

(S)-lactaldehyde + NAD(+) + H2O = (S)-lactate + NADH + 2 H(+)

Direction not assertedBalancedRhea 14277

2 Fe(III)-[cytochrome c] + sulfite + H2O = 2 Fe(II)-[cytochrome c] + sulfate + 2 H(+)

Direction not assertedBalance undeterminableRhea 14281

sn-glycerol 3-phosphate + UDP-alpha-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + UDP + H(+)

Direction not assertedBalancedRhea 14285

a dicarboxylate + ATP + CoA = omega-dicarboxyl-CoA + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 14289

D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)

Left to rightBalancedRhea 14293

a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine

Left to rightBalance undeterminableRhea 14297

4-pyridoxolactone + H2O = 4-pyridoxate + H(+)

Direction not assertedBalancedRhea 14301

tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate

Left to rightBalancedRhea 14305

2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 14313

morphine + NAD(+) = morphinone + NADH + H(+)

Direction not assertedBalancedRhea 14317

morphine + NADP(+) = morphinone + NADPH + H(+)

Direction not assertedBalancedRhea 14321

7,8-dihydroxycoumarin + UDP-alpha-D-glucose = daphnin + UDP + H(+)

Direction not assertedBalancedRhea 14325

O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate

Right to leftBalancedRhea 14329

a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol = 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 14333

UDP-N-acetyl-alpha-D-galactosamine 4-sulfate + 3'-phosphoadenylyl sulfate = UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 14337

glyoxylate + 2-oxoglutarate + H(+) = 2-hydroxy-3-oxoadipate + CO2

Direction not assertedBalancedRhea 14341

L-tyrosine + H(+) = tyramine + CO2

Direction not assertedBalancedRhea 14345

an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-alpha-D-galactose = an alpha-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + UDP + H(+)

Left to rightBalance undeterminableRhea 14349

3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO2

Direction not assertedBalancedRhea 14353

riboflavin + ATP = FMN + ADP + H(+)

Left to rightBalancedRhea 14357

N-carbamoyl-L-aspartate + H2O + 2 H(+) = L-aspartate + NH4(+) + CO2

Direction not assertedBalancedRhea 14365

2-phosphoglycolate + H2O = glycolate + phosphate

Direction not assertedBalancedRhea 14369

5beta-cholestane-3alpha,7alpha,12alpha-triol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 14373

(3R)-3-hydroxy-L-aspartate = glyoxylate + glycine

Direction not assertedBalancedRhea 14377

4-guanidinobutanal + NAD(+) + H2O = 4-guanidinobutanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 14381

a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 14385

a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 14389

N-terminal L-alanyl-[cypemycin] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-alanyl-[cypemycin] + 2 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 14393

(3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) = (4Z)-2-oxohept-4-enedioate + CO2

Direction not assertedBalancedRhea 14397

chlordecone alcohol + NADP(+) = chlordecone + NADPH + H(+)

Direction not assertedBalancedRhea 14401

D-glucose + NADP(+) = D-glucono-1,5-lactone + NADPH + H(+)

Left to rightBalancedRhea 14405

cysteamine + O2 = hypotaurine + H(+)

Left to rightBalancedRhea 14409

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