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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,401–10,450 of 18,558 reactions from Rhea

beta-muricholate + deoxycholoyl-CoA = beta-muricholoyl-CoA + deoxycholate
Direction not assertedBalancedRhea 53784
beta-muricholate + allodeoxycholoyl-CoA = beta-muricholoyl-CoA + allodeoxycholate
Direction not assertedBalancedRhea 53788
benzylthiol + O2 = benzothialdehyde + H2O2
Direction not assertedBalancedRhea 53792
deoxycholoyl-CoA + ursodeoxycholate = ursodeoxycholoyl-CoA + deoxycholate
Direction not assertedBalancedRhea 53796
ursodeoxycholate + lithocholoyl-CoA = ursodeoxycholoyl-CoA + lithocholate
Direction not assertedBalancedRhea 53800
allodeoxycholoyl-CoA + ursodeoxycholate = ursodeoxycholoyl-CoA + allodeoxycholate
Direction not assertedBalancedRhea 53804
cholestanol + reduced [NADPH--hemoprotein reductase] + O2 = (24S)-hydroxycholestanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53808

cholestanol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-26-hydroxycholestanol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 53812

O-succinyl-L-serine + hydrogen sulfide = L-cysteine + succinate

Direction not assertedBalancedRhea 53816

chenodeoxycholate + NADP(+) = 7-oxolithocholate + NADPH + H(+)

Right to leftBalancedRhea 53820

taurochenodeoxycholate + NAD(+) = 7-oxotaurolithocholate + NADH + H(+)

Direction not assertedBalancedRhea 53824

a 5-hydroxymethyl-2'-deoxycytidine in DNA + 2-oxoglutarate + O2 = a 5-formyl-2'-deoxycytidine in DNA + succinate + CO2 + H2O

Direction not assertedBalance undeterminableRhea 53828

a 5-formyl-2'-deoxycytidine in DNA + 2-oxoglutarate + O2 = a 5-carboxyl-2'-deoxycytidine in DNA + succinate + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 53832

a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a (3R)-hydroxyacyl-[ACP] = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 53836

3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADP(+) = 7,12-dioxo-lithocholate + NADPH + H(+)

Direction not assertedBalancedRhea 53840

glycochenodeoxycholate + NAD(+) = 7-oxoglycolithocholate + NADH + H(+)

Direction not assertedBalancedRhea 53844

taurocholate + NAD(+) = 7-oxo-taurodeoxycholate + NADH + H(+)

Direction not assertedBalancedRhea 53848

glycocholate + NAD(+) = 7-oxo-glycodeoxycholate + NADH + H(+)

Direction not assertedBalancedRhea 53852

ursocholate + NADP(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADPH + H(+)

Direction not assertedBalancedRhea 53856

7beta-hydroxy-3,12-dioxo-5beta-cholan-24-oate + NADP(+) = dehydrocholate + NADPH + H(+)

Direction not assertedBalancedRhea 53860

3alpha,7beta-dihydroxy-12-oxo-5beta-cholan-24-oate + NADP(+) = 7,12-dioxo-lithocholate + NADPH + H(+)

Direction not assertedBalancedRhea 53864

phenazine-1-carboxylate + NADH + O2 + 2 H(+) = 1-hydroxyphenazine + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 53868

D-ribose 5-phosphate + CTP + H(+) = CDP-D-ribose + diphosphate

Direction not assertedBalancedRhea 53872

a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)

Direction not assertedBalance undeterminableRhea 53876

ADP-alpha-D-glucose + D-glucose 6-phosphate = alpha,alpha-trehalose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 53880

CDP-alpha-D-glucose + D-glucose 6-phosphate = alpha,alpha-trehalose 6-phosphate + CDP + H(+)

Direction not assertedBalancedRhea 53884

TDP-alpha-D-glucose + D-glucose 6-phosphate = 5-methyl-UDP + alpha,alpha-trehalose 6-phosphate + H(+)

Direction not assertedBalancedRhea 53888

an S-polyprenyl-L-cysteine + O2 + H2O = a polyprenal + L-cysteine + H2O2

Left to rightBalance undeterminableRhea 53892

an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+)

Left to rightBalance undeterminableRhea 53896

L-threonyl-[myosin light chain] + ATP = O-phospho-L-threonyl-[myosin light chain] + ADP + H(+)

Left to rightBalance undeterminableRhea 53900

L-threonyl-[tau protein] + ATP = O-phospho-L-threonyl-[tau protein] + ADP + H(+)

Left to rightBalance undeterminableRhea 53904

(2E)-butenoyl-CoA + L-lysyl-[protein] = N(6)-(2E)-butenoyl-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 53908

butanoyl-CoA + L-lysyl-[protein] = N(6)-butanoyl-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 53912

an acyl-CoA + L-lysyl-[protein] = N(6)-acyl-L-lysyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 53916

L-threonyl-[Fas-activated protein] + ATP = O-phospho-L-threonyl-[Fas-activated protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 53920

a secondary amine + S-adenosyl-L-methionine = a methylated secondary amine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 53924

a tertiary amine + S-adenosyl-L-methionine = a methylated tertiary amine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 53928

prostaglandin I2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-prostaglandin I2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53932

thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53936

thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53940

2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP(+) = (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one + NADPH + H(+)

Direction not assertedBalancedRhea 53944

holo-[BtrI ACP] + L-glutamate + ATP = gamma-L-glutamyl-[BtrI ACP] + ADP + phosphate

Direction not assertedBalance undeterminableRhea 53948

4-aminobutanoyl-[BtrI ACP] + L-glutamate + ATP = 4-(gamma-L-glutamylamino)butanoyl-[BtrI ACP] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 53952

gamma-L-glutamyl-[BtrI ACP] + H(+) = 4-aminobutanoyl-[BtrI ACP] + CO2

Direction not assertedBalance undeterminableRhea 53956

4-(gamma-L-glutamylamino)butanoyl-[BtrI ACP] + FMNH2 + O2 = 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53960

4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin = gamma-L-glutamyl-butirosin B + holo-[BtrI ACP] + H(+)

Direction not assertedBalance undeterminableRhea 53964

apo-[BtrI ACP] + CoA = holo-[BtrI ACP] + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 53968

(8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O = (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 53972

(14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate

Left to rightBalancedRhea 53976

(11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 53980

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