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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

Evidence

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Outcomes
Proteins
Interactions
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Reactions
Reach

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Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,351–10,400 of 18,558 reactions from Rhea

resolvin D2 + NAD(+) = 7-oxoresolvin D2 + NADH + H(+)
Left to rightBalancedRhea 53584
resolvin D2 + NAD(+) = 16-oxoresolvin D2 + NADH + H(+)
Left to rightBalancedRhea 53588
1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate
Left to rightBalancedRhea 53592
1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate
Left to rightBalancedRhea 53596
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate
Left to rightBalancedRhea 53600
1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate
Left to rightBalancedRhea 53604
4-hydroxyestrone + O2 = (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)

Direction not assertedBalancedRhea 53608

D-ribulose 5-phosphate + CTP + H(+) = CDP-D-ribulose + diphosphate

Direction not assertedBalancedRhea 53612

(2E,6E)-farnesyl diphosphate + H2O = (+)-isoafricanol + diphosphate

Direction not assertedBalancedRhea 53616

(2E,6E,10E)-geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate

Direction not assertedBalancedRhea 53620

(2E,6E,10E)-geranylgeranyl diphosphate = tsukubadiene + diphosphate

Direction not assertedBalancedRhea 53624

(2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate

Direction not assertedBalancedRhea 53628

(2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate

Direction not assertedBalancedRhea 53632

a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 53636

(2E,6E)-farnesyl diphosphate = (-)-alpha-amorphene + diphosphate

Direction not assertedBalancedRhea 53640

(2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether B + diphosphate

Direction not assertedBalancedRhea 53644

(2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether A + diphosphate

Direction not assertedBalancedRhea 53648

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53652

(5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 = (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53656

(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53660

(2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + NH4(+) = pyridinestrone carboxylate + 2 H2O + H(+)

Direction not assertedBalancedRhea 53664

(2E,6E)-farnesyl diphosphate = (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate

Direction not assertedBalancedRhea 53668

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O

Direction not assertedBalancedRhea 53672

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Left to rightBalancedRhea 53676

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Left to rightBalancedRhea 53680

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O

Left to rightBalancedRhea 53684

2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)

Left to rightBalancedRhea 53688

2-(prostaglandin E2)-sn-glycero-3-phosphocholine + H2O = prostaglandin E2 + sn-glycerol 3-phosphocholine + H(+)

Left to rightBalancedRhea 53692

2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)

Left to rightBalancedRhea 53696

2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)

Left to rightBalancedRhea 53700

2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + prostaglandin E2 + H(+)

Left to rightBalancedRhea 53704

(2E)-decenoyl-CoA + NADP(+) = (2E,4Z)-decadienoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 53708

2 Fe(III)-heme b = beta-hematin

Direction not assertedBalancedRhea 53712

N-acetyl-alpha-D-muramate 1-phosphate + UDP + H(+) = UDP-N-acetyl-alpha-D-muramate + phosphate

Direction not assertedBalancedRhea 53716

N-acetyl-D-muramate + ATP = N-acetyl-alpha-D-muramate 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 53720

N-acetyl-D-glucosamine + ATP = N-acetyl-alpha-D-glucosamine 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 53724

N-acetyl-D-muramate 6-phosphate + H2O = N-acetyl-D-muramate + phosphate

Direction not assertedBalancedRhea 53728

4-aminosalicylate + (7,8-dihydropterin-6-yl)methyl diphosphate = 2-hydroxy-7,8-dihydropteroate + diphosphate

Direction not assertedBalancedRhea 53732

a 2-halobenzoate + NADH + O2 + H(+) = a halide anion + catechol + CO2 + NAD(+)

Direction not assertedBalance undeterminableRhea 53736

[Rab1 protein]-O(4)-(5'-adenylyl)-L-tyrosine + H2O = [Rab1 protein]-L-tyrosine + AMP + H(+)

Direction not assertedBalance undeterminableRhea 53740

glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)

Direction not assertedBalancedRhea 53744

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + UDP + H(+)

Direction not assertedBalance undeterminableRhea 53748

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-glucose = a 1,2-diacyl-3-O-[beta-D-glucopyranosyl-(1->6)-beta-D-galactopyranosyl]-sn-glycerol + UDP + H(+)

Direction not assertedBalance undeterminableRhea 53752

allodeoxycholoyl-CoA + cholate = allodeoxycholate + choloyl-CoA

Direction not assertedBalancedRhea 53756

allocholate + deoxycholoyl-CoA = allocholoyl-CoA + deoxycholate

Direction not assertedBalancedRhea 53760

allocholate + lithocholoyl-CoA = allocholoyl-CoA + lithocholate

Direction not assertedBalancedRhea 53764

allocholate + allodeoxycholoyl-CoA = allocholoyl-CoA + allodeoxycholate

Direction not assertedBalancedRhea 53768

lithocholoyl-CoA + chenodeoxycholate = chenodeoxycholoyl-CoA + lithocholate

Direction not assertedBalancedRhea 53772

3-sulfanylpropanoate + O2 = 3-sulfinopropanoate + H(+)

Direction not assertedBalancedRhea 53776

beta-muricholate + lithocholoyl-CoA = beta-muricholoyl-CoA + lithocholate

Direction not assertedBalancedRhea 53780

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