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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,251–10,300 of 18,558 reactions from Rhea

1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O = 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)
Left to rightBalancedRhea 53184
1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-9Z-octadecenoyl)-ethanolamine + H2O = 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-(9Z-octadecenoyl) ethanolamine + H(+)
Left to rightBalancedRhea 53188
1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H2O = 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + H(+)
Left to rightBalancedRhea 53192
testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 53196
17beta-hydroxy-5alpha-androstan-3-one + reduced [NADPH--hemoprotein reductase] + O2 = 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to rightBalance undeterminableRhea 53200
17beta,19-dihydroxy-3-oxo-5alpha-androstanone + reduced [NADPH--hemoprotein reductase] + O2 = 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 53204

daidzein + reduced [NADPH--hemoprotein reductase] + O2 = 2'-hydroxydaidzein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53208

17beta-hydroxy-5alpha-androstan-3-one + reduced [NADPH--hemoprotein reductase] + O2 = 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53212

17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53216

16alpha,17alpha-dihydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta,16alpha,17alpha-trihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53220

16alpha,17alpha-dihydroxypregnenolone + reduced [NADPH--hemoprotein reductase] + O2 = 3beta,16alpha-dihydroxy-androst-5-en-17-one + acetate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 53224

androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53228

desmosterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S)-25-epoxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53232

desmosterol + reduced [NADPH--hemoprotein reductase] + O2 = (24Z),26-hydroxydesmosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53236

7-dehydrocholesterol + reduced [NADPH--hemoprotein reductase] + O2 = cholesta-5,7-dien-3beta,25-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53240

7-dehydrocholesterol + reduced [NADPH--hemoprotein reductase] + O2 = cholesta-5,7-dien-3beta,24S-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53244

7-dehydrocholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 7-oxocholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53248

lathosterol + reduced [NADPH--hemoprotein reductase] + O2 = 5alpha-cholestan-7-oxo-3beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53252

lathosterol + reduced [NADPH--hemoprotein reductase] + O2 = 7alpha,8alpha-epoxy-5alpha-cholestan-3beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53256

testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 1beta-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53260

testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 2beta-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53264

L-ribulose = L-xylulose

Direction not assertedBalancedRhea 53268

5-dehydro-L-gluconate = keto-D-tagaturonate

Direction not assertedBalancedRhea 53272

17beta-hydroxy-3,19-dioxo-5alpha-androstanone + reduced [NADPH--hemoprotein reductase] + O2 = 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 53276

D-threose = D-erythrulose

Direction not assertedBalancedRhea 53280

scyllo-inosose + NAD(+) = 3-dehydro-scyllo-inosose + NADH + H(+)

Direction not assertedBalancedRhea 53284

3-dehydro-scyllo-inosose + H2O = 5-dehydro-L-gluconate + H(+)

Direction not assertedBalancedRhea 53288

L-5-[2-(methysulfanyl)ethyl]hydantoin + H2O = N-carbamoyl-L-methionine + H(+)

Direction not assertedBalancedRhea 53292

(2E)-decenoyl-CoA + NADP(+) = (2E,4E)-decadienoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 53296

D-5-[2-(methylsulfanyl)ethyl]hydantoin + H2O = N-carbamoyl-D-methionine + H(+)

Direction not assertedBalancedRhea 53300

2 cob(II)alamin + AH2 + 2 ATP = 2 adenosylcob(III)alamin + 2 triphosphate + A + 2 H(+)

Direction not assertedBalancedRhea 53304

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16(R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53308

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53312

N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose = alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)

Direction not assertedBalancedRhea 53316

alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)

Direction not assertedBalancedRhea 53320

2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin E2

Left to rightBalancedRhea 53324

UDP-2,3-diacyl-alpha-D-glucosamine + H2O = 2,3-diacyl-alpha-D-glucosaminyl 1-phosphate + UMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 53328

2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-glycerol

Left to rightBalancedRhea 53332

5,6-dihydrouridine(20) in tRNA + NADP(+) = uridine(20) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53336

5,6-dihydrouridine(20) in tRNA + NAD(+) = uridine(20) in tRNA + NADH + H(+)

Direction not assertedBalancedRhea 53340

5,6-dihydrouridine(20a) in tRNA + NADP(+) = uridine(20a) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53344

5,6-dihydrouridine(20a) in tRNA + NAD(+) = uridine(20a) in tRNA + NADH + H(+)

Right to leftBalancedRhea 53348

5,6-dihydrouridine(20b) in tRNA + NAD(+) = uridine(20b) in tRNA + NADH + H(+)

Right to leftBalancedRhea 53352

5,6-dihydrouridine(20b) in tRNA + NADP(+) = uridine(20b) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53356

5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53360

5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)

Right to leftBalancedRhea 53364

5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53368

5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)

Right to leftBalancedRhea 53372

5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)

Right to leftBalancedRhea 53376

5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)

Right to leftBalancedRhea 53380

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