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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,201–10,250 of 18,558 reactions from Rhea

7-oxoheptanoyl-[ACP] + oxidized [flavodoxin] + H2O = 6-carboxyhexanoyl-[ACP] + reduced [flavodoxin]
Direction not assertedBalance undeterminableRhea 52984
dehydrospermidine + [deoxyhypusine synthase]-L-lysine = [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine
Direction not assertedBalance undeterminableRhea 52988
[eIF5A protein]-L-lysine + [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine = [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine
Direction not assertedBalance undeterminableRhea 52992
[eIF5A protein]-N-(4-aminobutylidene)-L-lysine + NADH + H(+) = [eIF5A protein]-deoxyhypusine + NAD(+)
Direction not assertedBalance undeterminableRhea 52996
17beta-hydroxy-5alpha-androstan-3-one + UDP-alpha-D-glucuronate = 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + UDP + H(+)
Left to rightBalancedRhea 53000
2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)

→ Left to right

Balanced

Rhea 53004

n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate

Direction not assertedBalance undeterminableRhea 53008

2,5-dichlorohydroquinone + 2 glutathione = chlorohydroquinone + glutathione disulfide + chloride + H(+)

Direction not assertedBalancedRhea 53012

chlorohydroquinone + 2 glutathione = hydroquinone + glutathione disulfide + chloride + H(+)

Direction not assertedBalancedRhea 53016

a plastoquinone + an L-alpha-amino acid + H2O = a plastoquinol + a 2-oxocarboxylate + NH4(+)

Direction not assertedBalance undeterminableRhea 53020

a plastoquinone + L-arginine + H2O = a plastoquinol + 5-guanidino-2-oxopentanoate + NH4(+)

Direction not assertedBalance undeterminableRhea 53024

lithocholate + UDP-alpha-D-glucuronate = lithocholoyl-3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53028

2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 2-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53032

4-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53036

4-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 4-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53040

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-ribonucleotide in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 53044

2-hydroxyestrone + UDP-alpha-D-glucuronate = 2-hydroxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53048

4-hydroxyestrone + UDP-alpha-D-glucuronate = 4-hydroxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53052

4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = isowyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 53056

4-hydroxyestrone + UDP-alpha-D-glucuronate = estrone 4-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53060

2-methoxyestrone + UDP-alpha-D-glucuronate = 2-methoxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53064

4-methoxyestrone + UDP-alpha-D-glucuronate = 4-methoxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53068

2-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53072

cytidine(34) in mitochondrial tRNA + S-adenosyl-L-methionine = 5-methylcytidine(34) in mitochondrial tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53076

4-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate = 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 53080

[(1->2)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->2)-beta-D-glucosyl](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 53084

2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 2-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53088

2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53092

4-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 4-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53096

2-hydroxyestrone + S-adenosyl-L-methionine = 2-methoxyestrone + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53100

4-hydroxyestrone + S-adenosyl-L-methionine = 4-methoxyestrone + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53104

2-hydroxyestrone + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-estrone + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 53108

3alpha-hydroxy-5alpha-androstane 17-O-(beta-D-glucuronate) + NADP(+) = 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + NADPH + H(+)

Right to leftBalancedRhea 53112

an 11beta-hydroxysteroid + NAD(+) = an 11-oxosteroid + NADH + H(+)

Left to rightBalance undeterminableRhea 53116

(3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate + NADP(+) = 5alpha-dihydrotestosterone sulfate + NADPH + H(+)

Right to leftBalancedRhea 53120

all-trans-lycopene = delta-carotene

Direction not assertedBalancedRhea 53124

delta-carotene = epsilon-carotene

Direction not assertedBalancedRhea 53128

a 3-oxo-Delta(4)-steroid + A = a 3-oxo-Delta(1,4)-steroid + AH2

Direction not assertedBalance undeterminableRhea 53132

(3alpha,5alpha,17beta)-3-hydroxy-androstan-17-yl sulfate + NADP(+) = 5alpha-dihydrotestosterone sulfate + NADPH + H(+)

Right to leftBalancedRhea 53136

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53140

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53144

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53148

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53152

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(5,6-epoxy-8Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 53156

N-acyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + sn-glycerol 3-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 53160

N,1-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1-acyl-sn-glycero-3-phosphate + H(+)

Left to rightBalance undeterminableRhea 53164

N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-hexadecanoylethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)

Left to rightBalancedRhea 53168

1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+)

Left to rightBalancedRhea 53172

N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)

Direction not assertedBalance undeterminableRhea 53176

D-erythrose = D-erythrulose

Direction not assertedBalancedRhea 53180

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