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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

10,051–10,100 of 18,558 reactions from Rhea

(+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) = (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)
Direction not assertedBalance undeterminableRhea 52376
a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)
Left to rightBalance undeterminableRhea 52380
O-phospho-L-serine + L-glutamate = N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate + H(+)
Direction not assertedBalancedRhea 52384
D-threonate + ATP = 4-O-phospho-D-threonate + ADP + H(+)
Direction not assertedBalancedRhea 52388
D-erythronate + ATP = 4-phospho-D-erythronate + ADP + H(+)
Direction not assertedBalancedRhea 52392
4-O-phospho-D-threonate + NAD(+) = dihydroxyacetone phosphate + CO2 + NADH
Direction not asserted

Balanced

Rhea 52396

4-O-phospho-D-threonate + NAD(+) = 3-dehydro-4-O-phospho-L-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52400

3-dehydro-4-O-phospho-L-erythronate + H(+) = dihydroxyacetone phosphate + CO2

Direction not assertedBalancedRhea 52404

4-phospho-D-erythronate + NAD(+) = dihydroxyacetone phosphate + CO2 + NADH

Direction not assertedBalancedRhea 52408

4-phospho-D-erythronate + NAD(+) = 3-dehydro-4-O-phospho-D-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52412

3-dehydro-4-O-phospho-D-erythronate + H(+) = dihydroxyacetone phosphate + CO2

Direction not assertedBalancedRhea 52416

O-phospho-L-serine + thiosulfate = S-sulfo-L-cysteine + phosphate

Direction not assertedBalancedRhea 52420

L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 52424

12-oxo-leukotriene B4 + NADH + H(+) = 12-oxo-(5S)-hydroxy-(6Z,8E,14Z)-eicosatrienoate + NAD(+)

Direction not assertedBalancedRhea 52428

(R)-2,3-diaminopropanoate + H2O + H(+) = pyruvate + 2 NH4(+)

Direction not assertedBalancedRhea 52432

a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + an acyl-CoA = a 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + CoA

Direction not assertedBalance undeterminableRhea 52436

a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)

Direction not assertedBalance undeterminableRhea 52440

a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = a 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)

Direction not assertedBalance undeterminableRhea 52444

16alpha-hydroxyestrone + UDP-alpha-D-glucuronate = 16alpha-hydroxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52448

16alpha-hydroxyestrone + UDP-alpha-D-glucuronate = 16alpha-hydroxyestrone 16-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52452

testosterone + UDP-alpha-D-glucuronate = testosterone 17-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52456

17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52460

17beta-estradiol + UDP-alpha-D-glucuronate = 17beta-estradiol 17-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52464

16alpha,17beta-estriol + UDP-alpha-D-glucuronate = 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52468

16alpha,17beta-estriol + UDP-alpha-D-glucuronate = 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52472

estrone + UDP-alpha-D-glucuronate = estrone 3-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52476

16-methoxytabersonine + reduced [NADPH--hemoprotein reductase] + O2 = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52480

(3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + A = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + AH2

Direction not assertedBalancedRhea 52484

prostaglandin E2 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin E2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52488

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52492

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52496

(9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52500

(9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52504

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52508

trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)

Direction not assertedBalance undeterminableRhea 52512

ubiquinone-10 + trans-4-hydroxy-L-proline = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + ubiquinol-10 + H(+)

Direction not assertedBalancedRhea 52516

prostaglandin E1 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin E1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52520

prostaglandin A1 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52524

L-asparagine + 2-oxoglutarate = 2-oxosuccinamate + L-glutamate

Direction not assertedBalancedRhea 52528

adenosine + GTP = GDP + AMP + H(+)

Direction not assertedBalancedRhea 52532

dGTP + adenosine = dGDP + AMP + H(+)

Direction not assertedBalancedRhea 52536

cytidine + phosphate = cytosine + alpha-D-ribose 1-phosphate

Direction not assertedBalancedRhea 52540

D-erythronate + NAD(+) = 2-dehydro-D-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52544

L-threonate + NAD(+) = 2-dehydro-L-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52548

3-dehydro-L-erythronate + ATP = 3-dehydro-4-O-phospho-L-erythronate + ADP + H(+)

Direction not assertedBalancedRhea 52552

3-dehydro-D-erythronate + ATP = 3-dehydro-4-O-phospho-D-erythronate + ADP + H(+)

Direction not assertedBalancedRhea 52556

2-dehydro-D-erythronate = 3-dehydro-D-erythronate

Direction not assertedBalancedRhea 52560

2-dehydro-L-erythronate = 3-dehydro-L-erythronate

Direction not assertedBalancedRhea 52564

epitestosterone + UDP-alpha-D-glucuronate = epitestosterone 17-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52568

butanoyl-CoA + NAD(+) = (2E)-butenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52572

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