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Subsystem: Steroid metabolism Remove
51–92 of 92 reactions in Steroid metabolism
17alpha-hydroxyprogesterone[r] + H+[r] + NADPH[r] + O2[r] = 11-deoxycortisol[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.16Human-GEM MAR07928
NAD+[c] + pregnenolone[c] = H+[c] + NADH[c] + progesterone[c]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07930
NAD+[r] + pregnenolone[r] = H+[r] + NADH[r] + progesterone[r]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07931
H+[r] + NADPH[r] + O2[r] + progesterone[r] = 11-deoxycorticosterone[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.16Human-GEM MAR07932
11-deoxycorticosterone[m] + H+[m] + NADPH[m] + 2 O2[m] = aldosterone[m] + 2 H2O[m] + NADP+[m]
Left to rightBalanced
cholesterol[m] + H+[m] + NADPH[m] + 2 O2[m] = 2 H2O[m] + isocaproic-aldehyde[m] + NADP+[m] + pregnenolone[m]
Left to rightBalancedEC 1.14.15.6Human-GEM MAR07935
17alpha-hydroxypregnenolone[r] + H+[r] + NADPH[r] + 0.5 O2[r] = acetaldehyde[r] + dehydroepiandrosterone[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.19Human-GEM MAR07936
H+[r] + NADPH[r] + O2[r] + progesterone[r] = 17alpha-hydroxyprogesterone[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.19Human-GEM MAR07937
17alpha-hydroxyprogesterone[r] + H+[r] + NADPH[r] + 0.5 O2[r] = 4-androstene-3,17-dione[r] + acetaldehyde[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.19Human-GEM MAR07938
17alpha-hydroxypregnenolone[r] + NAD+[r] = 17alpha-hydroxyprogesterone[r] + H+[r] + NADH[r]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07939
4-androstene-3,17-dione[r] + NADPH[r] + 2 O2[r] = estrone[r] + formate[r] + 2 H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.14Human-GEM MAR07940
NADPH[r] + 2 O2[r] + testosterone[r] = estradiol-17beta[r] + formate[r] + 2 H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.14Human-GEM MAR07941
cortisone[r] + H+[r] + NADPH[r] = cortisol[r] + NADP+[r]
ReversibleBalancedEC 1.1.1.146Human-GEM MAR07942
cortisone[r] + H+[r] + NADH[r] = cortisol[r] + NAD+[r]
ReversibleBalancedEC 1.1.1.-Human-GEM MAR07943
estrone 3-sulfate[r] + H2O[r] = estrone[r] + H+[r] + sulfate[r]
Left to rightBalancedEC 3.1.6.2Human-GEM MAR07945
H2O[r] + pregnenolone sulfate[r] = H+[r] + pregnenolone[r] + sulfate[r]
Left to rightBalancedEC 3.1.6.2Human-GEM MAR07948
cholesterol-sulfate[r] + H2O[r] = cholesterol[r] + H+[r] + sulfate[r]
Left to rightBalancedEC 3.1.6.2Human-GEM MAR07950
dehydroepiandrosterone sulfate[r] + H2O[r] = dehydroepiandrosterone[r] + H+[r] + sulfate[r]
Left to rightBalancedEC 3.1.6.2Human-GEM MAR07952
dehydroepiandrosterone[r] + NAD+[r] = 4-androstene-3,17-dione[r] + H+[r] + NADH[r]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07954
4-androstene-3,17-dione[r] + H+[r] + NADH[r] = NAD+[r] + testosterone[r]
Left to rightBalancedEC 1.1.1.239Human-GEM MAR07955
H+[r] + NADPH[r] + O2[r] + testosterone[r] = 19-hydroxytestosterone[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07957
H+[r] + NADPH[r] + O2[r] + testosterone[r] = 6beta-hydroxytestosterone[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07958
testosterone[r] + UDP-glucuronate[r] = testosterone glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07959
estrone[r] + UDP-glucuronate[r] = estrone-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07962
androsterone[r] + UDP-glucuronate[r] = androsterone-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07965
estrone[r] + H+[r] + NADH[r] = estradiol-17beta[r] + NAD+[r]
Left to rightBalancedEC 1.1.1.62, 1.1.1.64Human-GEM MAR07968
androsterone[r] + H+[r] + NADPH[r] + 1.5 O2[r] = 16alpha-hydroxydehydroepiandrosterone[r] + 2 H2O[r] + NADP+[r]
Left to rightBalancedEC 1.1.1.270Human-GEM MAR07970
16alpha-hydroxydehydroepiandrosterone[r] + H+[r] + NADH[r] = 5alpha-androstane-3,17-dione[r] + H2O[r] + NAD+[r]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07971
16alpha-hydroxydehydroepiandrosterone[r] + H+[r] + NADPH[r] = 5alpha-androstane-3,17-dione[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07972
17alpha-hydroxypregnenolone[c] + NAD+[c] = 17alpha-hydroxyprogesterone[c] + H+[c] + NADH[c]
Left to rightBalancedEC 5.3.3.1Human-GEM MAR07973
5-alpha-dihydrotestosterone[c] + PAPS[c] = 5alpha-dihydrotestosterone-sulfate[c] + H+[c] + PAP[c]
Left to rightBalancedEC 2.8.2.14Human-GEM MAR07974
H+[c] + NADPH[c] + progesterone[c] = 20alpha-hydroxy-4-pregnen-3-one[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.149Human-GEM MAR07976
PAPS[c] + testosterone[c] = H+[c] + PAP[c] + testosterone sulfate[c]
Left to rightBalancedEC 2.8.2.14Human-GEM MAR07978
etiocholanolone[r] + UDP-glucuronate[r] = etiocholan-3alpha-ol-17-one 3-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07980
estriol[r] + UDP-glucuronate[r] = 16-glucuronide-estriol[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07984
5-alpha-dihydrotestosterone[r] + UDP-glucuronate[r] = 5alpha-dihydrotestosterone-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07987
4-androstene-3,17-dione[c] + H+[c] + NADPH[c] + O2[c] = H2O[c] + NADP+[c] + 19-Hydroxyandrost-4-Ene-3,17-Dione[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR09937
20alpha-hydroxy-4-pregnen-3-one[c] + NAD+[c] = H+[c] + NADH[c] + progesterone[c]
Left to rightBalancedEC 1.1.1.149Human-GEM MAR10066
NADP+[c] + 5alpha-Pregnan-20alpha-ol-3-one[c] = 5alpha-pregnane-3,20-dione[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.-Human-GEM MAR10071
NADP+[c] + 17alpha,20alpha-Dihydroxypregn-4-en-3-one[c] = 17alpha-hydroxyprogesterone[c] + H+[c] + NADPH[c]
Left to rightBalancedEC 1.1.1.-Human-GEM MAR10072
estradiol-17beta[r] + H+[r] + NADPH[r] + O2[r] = estriol[r] + H2O[r] + NADP+[r]
Left to rightBalancedHuman-GEM MAR11368
16alpha-hydroxyestrone[r] + H+[r] + NADH[r] = estriol[r] + NAD+[r]
Left to rightBalancedEC 6.2.1.2Human-GEM MAR11369