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Subsystem: Retinol metabolism Remove
51–93 of 93 reactions in Retinol metabolism
13-cis-retinoate[r] + UDP-glucuronate[r] = 13-cis-retinoyl-beta-D-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR06680
13-cis-retinoate[c] + H+[c] + NADPH[c] + O2[c] = 4-oxo-13-cis-retinoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06681
13-cis-retinoate[r] + H+[r] + NADPH[r] + O2[r] = 4-oxo-13-cis-retinoate[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06682
13-cis-retinoate[c] + H+[c] + NADPH[c] + O2[c] = 5,6-epoxy-13-cis-retinoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06683
13-cis-retinoate[r] + H+[r] + NADPH[r] + O2[r] = 5,6-epoxy-13-cis-retinoate[r] + H2O[r] + NADP+[r]
Left to right
5,6-epoxy-13-cis-retinoate[c] + UDP-glucuronate[c] = rac-5,6-epoxy-retinoyl-beta-D-glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR06685
5,6-epoxy-13-cis-retinoate[r] + UDP-glucuronate[r] = rac-5,6-epoxy-retinoyl-beta-D-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR06686
13-cis-retinoate[c] + H+[c] + NADPH[c] + O2[c] = 5,8-epoxy-13-cis-retinoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06687
APE[c] + H+[c] + H2O[c] = PE-LD pool[c] + retinal[c]
ReversibleBalance undeterminableHuman-GEM MAR06690
A2PE-H2[c] + H2O[c] = APE[c] + H+[c] + retinal[c]
ReversibleBalance undeterminableHuman-GEM MAR06691
A2PE-H2[c] + FAD[c] = A2PE[c] + FADH2[c]
ReversibleBalance undeterminableHuman-GEM MAR06692
A2PE[c] + H2O[c] = H+[c] + N-retinylidene-N-retinylethanolamine[c] + phosphatidate-LD-PE pool[c]
ReversibleBalance undeterminableHuman-GEM MAR06693
N-retinylidene-N-retinylethanolamine[c] = iso-A2E(13-cis)[c]
ReversibleBalancedHuman-GEM MAR06694
N-retinylidene-N-retinylethanolamine[c] = iso-A2E(11-cis)[c]
ReversibleBalancedHuman-GEM MAR06695
N-retinylidene-N-retinylethanolamine[c] = iso-A2E(9-cis)[c]
ReversibleBalancedHuman-GEM MAR06697
N-retinylidene-N-retinylethanolamine[c] = iso-A2E(9,13-di-cis)[c]
ReversibleBalancedHuman-GEM MAR06699
H+[c] + NADPH[c] + O2[c] + retinoate[c] = 4-hydroxy-all-trans-retinoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06700
H+[r] + NADPH[r] + O2[r] + retinoate[r] = 4-hydroxy-all-trans-retinoate[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06701
4-hydroxy-all-trans-retinoate[c] + H+[c] + NADPH[c] + O2[c] = 4-oxo-all-trans-retinoate[c] + 2 H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06702
4-hydroxy-all-trans-retinoate[r] + H+[r] + NADPH[r] + O2[r] = 4-oxo-all-trans-retinoate[r] + 2 H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.-.-Human-GEM MAR06703
4-hydroxy-all-trans-retinoate[c] + UDP-glucuronate[c] = H+[c] + rac-4-hydroxy-4-O-(beta-D-glucuronide)-all-trans-retinoate[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR06704
4-hydroxy-all-trans-retinoate[r] + UDP-glucuronate[r] = H+[r] + rac-4-hydroxy-4-O-(beta-D-glucuronide)-all-trans-retinoate[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR06705
beta-carotene[c] + O2[c] = 2 retinal[c]
Left to rightBalancedEC 3.1.6.14Human-GEM MAR08697
2 H+[c] + NADPH[c] + retinoate[c] = H2O[c] + NADP+[c] + retinal[c]
ReversibleBalancedHuman-GEM MAR08698
13-cis-retinal[c] + H2O[c] + NADP+[c] = 13-cis-retinoate[c] + 2 H+[c] + NADPH[c]
ReversibleBalancedHuman-GEM MAR08699
H+[c] + NADPH[c] + O2[c] + retinoate[c] = 4-hydroxyretinoic acid[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR08700
9-cis-retinal[c] = retinal[c]
ReversibleBalancedHuman-GEM MAR08702
O2[c] + 2 retinoate[c] = 2 4-oxo-13-cis-retinoate[c]
Left to rightBalancedHuman-GEM MAR08703
13-cis-oxo-retinoate[c] = 4-oxo-13-cis-retinoate[c]
ReversibleBalancedHuman-GEM MAR08704
2 13-cis-retinoate[c] + O2[c] = 2 13-cis-oxo-retinoate[c]
Left to rightBalancedHuman-GEM MAR08706
11-cis-retinal[c] + H+[c] + NADPH[c] = 11-cis-retinol[c] + NADP+[c]
ReversibleBalancedEC 1.1.1.105Human-GEM MAR08709
13-cis-retinal[c] + H+[c] + NADH[c] = 13-cis-retinol[c] + NAD+[c]
ReversibleBalancedEC 1.1.1.315Human-GEM MAR08710
11-cis-retinol[c] = retinol[c]
ReversibleBalancedHuman-GEM MAR08711
ATP[c] + CoA[c] + retinoate[c] = AMP[c] + PPi[c] + retinoyl-CoA[c]
Left to rightBalancedHuman-GEM MAR08712
retinoate[r] + UDP-glucuronate[r] = retinoyl-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR08713
13-cis-retinoate[r] + UDP-glucuronate[r] = 13-cis-retinoyl-glucuronide[r] + UDP[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR08717
Left to rightBalancedEC 1.1.1.105Human-GEM MAR20001
Left to rightBalancedEC 1.1.1.315Human-GEM MAR20003
Left to rightBalancedEC 1.1.1.105Human-GEM MAR20005
Left to rightBalancedEC 1.1.1.-Human-GEM MAR20006
Left to rightBalancedEC 1.1.1.105Human-GEM MAR20007
Left to rightUnbalancedEC 1.1.1.-Human-GEM MAR20008
Left to rightBalancedEC 1.2.1.36Human-GEM MAR20011