Loading the page.
Subsystem: Leukotriene metabolism Remove
51–100 of 170 reactions in Leukotriene metabolism
20-dihydroxy-LTB4[r] + H+[r] + NADPH[r] + O2[r] = 20-trihydroxy-LTB4[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR01140
20-COOH-LTB4[r] + H+[r] + H2O[r] = 20-trihydroxy-LTB4[r]
ReversibleBalancedHuman-GEM MAR01142
5-oxo-6-trans-LTB4[c] + H+[c] + NADPH[c] = 6-trans-LTB4[c] + NADP+[c]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR01146
5-oxo-6-trans-LTB4[m] + H+[m] + NADPH[m] = 6-trans-LTB4[m] + NADP+[m]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR01147
5-oxo-6-trans-LTB4[x] + H+[x] + NADPH[x] = 6-trans-LTB4[x] + NADP+[x]
ReversibleBalancedEC 1.1.1.184Human-GEM
5-oxo-6-trans-LTB4[c] + H+[c] + NADPH[c] = 6,7-dihydro-5-oxo-LTB4[c] + NADP+[c]
ReversibleBalancedHuman-GEM MAR01149
5-oxo-6-trans-LTB4[m] + H+[m] + NADPH[m] = 6,7-dihydro-5-oxo-LTB4[m] + NADP+[m]
ReversibleBalancedHuman-GEM MAR01150
5-oxo-6-trans-LTB4[r] + H+[r] + NADPH[r] = 6,7-dihydro-5-oxo-LTB4[r] + NADP+[r]
ReversibleBalancedHuman-GEM MAR01151
5-oxo-6-trans-LTB4[x] + H+[x] + NADPH[x] = 6,7-dihydro-5-oxo-LTB4[x] + NADP+[x]
ReversibleBalancedHuman-GEM MAR01152
6,7-dihydro-5-oxo-LTB4[c] + H+[c] + NADPH[c] = 6,7-dihydro-LTB4[c] + NADP+[c]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01153
6,7-dihydro-5-oxo-LTB4[m] + H+[m] + NADPH[m] = 6,7-dihydro-LTB4[m] + NADP+[m]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01154
6,7-dihydro-5-oxo-LTB4[r] + H+[r] + NADPH[r] = 6,7-dihydro-LTB4[r] + NADP+[r]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01155
6,7-dihydro-5-oxo-LTB4[x] + H+[x] + NADPH[x] = 6,7-dihydro-LTB4[x] + NADP+[x]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01156
6,7-dihydro-5-oxo-LTB4[c] + ATP[c] + CoA[c] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01157
6,7-dihydro-5-oxo-LTB4[m] + ATP[m] + CoA[m] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01158
6,7-dihydro-5-oxo-LTB4[r] + ATP[r] + CoA[r] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01159
6,7-dihydro-5-oxo-LTB4[x] + ATP[x] + CoA[x] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01160
5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + O2[m] = 5-oxo-12(R)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[m] + H2O2[m]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01161
5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + FAD[x] = 5-oxo-12(R)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01162
5-oxo-12(R)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[m] + H2O[m] = 3(S),12(R)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01163
5-oxo-12(R)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[x] + H2O[x] = 3(S),12(R)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01164
3(S),12(R)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + NAD+[m] = 3,5-dioxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01165
3(S),12(R)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + NAD+[x] = 3,5-dioxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01166
3,5-dioxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + CoA[m] = 3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[m] + acetyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Human-GEM MAR01167
3,5-dioxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + CoA[x] = 3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Human-GEM MAR01168
3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[m] + H2O[m] = 3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoate[m] + CoA[m] + H+[m]
Left to rightBalancedEC 3.1.2.2Human-GEM MAR01170
3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[x] + H2O[x] = 3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoate[x] + CoA[x] + H+[x]
Left to rightBalancedEC 3.1.2.2Human-GEM MAR01171
5-oxo-(6E)-12-epi-LTB4[c] = 5-oxo-12-HETE[c]
ReversibleBalancedHuman-GEM MAR01186
5-oxo-(6E)-12-epi-LTB4[c] + H+[c] + NADPH[c] = 6-trans-12-epi-LTB4[c] + NADP+[c]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR01190
5-oxo-(6E)-12-epi-LTB4[m] + H+[m] + NADPH[m] = 6-trans-12-epi-LTB4[m] + NADP+[m]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR01191
5-oxo-(6E)-12-epi-LTB4[x] + H+[x] + NADPH[x] = 6-trans-12-epi-LTB4[x] + NADP+[x]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR01192
5-oxo-(6E)-12-epi-LTB4[c] + H+[c] + NADPH[c] = 6,7-dihydro-5-oxo-12-epi-LTB4[c] + NADP+[c]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01193
5-oxo-(6E)-12-epi-LTB4[m] + H+[m] + NADPH[m] = 6,7-dihydro-5-oxo-12-epi-LTB4[m] + NADP+[m]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01194
5-oxo-(6E)-12-epi-LTB4[r] + H+[r] + NADPH[r] = 6,7-dihydro-5-oxo-12-epi-LTB4[r] + NADP+[r]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01195
5-oxo-(6E)-12-epi-LTB4[x] + H+[x] + NADPH[x] = 6,7-dihydro-5-oxo-12-epi-LTB4[x] + NADP+[x]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR01196
6,7-dihydro-12-epi-LTB4[c] + NADP+[c] = 6,7-dihydro-5-oxo-12-epi-LTB4[c] + H+[c] + NADPH[c]
ReversibleBalancedHuman-GEM MAR01197
6,7-dihydro-12-epi-LTB4[m] + NADP+[m] = 6,7-dihydro-5-oxo-12-epi-LTB4[m] + H+[m] + NADPH[m]
ReversibleBalancedHuman-GEM MAR01198
6,7-dihydro-12-epi-LTB4[x] + NADP+[x] = 6,7-dihydro-5-oxo-12-epi-LTB4[x] + H+[x] + NADPH[x]
ReversibleBalancedHuman-GEM MAR01199
6,7-dihydro-5-oxo-12-epi-LTB4[c] + ATP[c] + CoA[c] = 5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01200
6,7-dihydro-5-oxo-12-epi-LTB4[m] + ATP[m] + CoA[m] = 5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01201
6,7-dihydro-5-oxo-12-epi-LTB4[r] + ATP[r] + CoA[r] = 5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01202
6,7-dihydro-5-oxo-12-epi-LTB4[x] + ATP[x] + CoA[x] = 5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Human-GEM MAR01203
5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + O2[m] = 5-oxo-12(S)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[m] + H2O2[m]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01204
5-oxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + FAD[x] = 5-oxo-12(S)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01205
5-oxo-12(S)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[m] + H2O[m] = 3(S),12(S)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[m]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01206
5-oxo-12(S)-hydroxy-eicosa-(2E,8E,10E,14Z)-tetraenoyl-CoA[x] + H2O[x] = 3(S),12(S)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[x]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01207
3(S),12(S)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + NAD+[m] = 3,5-dioxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01208
3(S),12(S)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + NAD+[x] = 3,5-dioxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01209
3,5-dioxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + CoA[m] = 3-oxo-10(S)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[m] + acetyl-CoA[m]
Left to rightBalancedEC 2.3.1.16, 1.1.1.211Human-GEM MAR01210
3,5-dioxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + CoA[x] = 3-oxo-10(S)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[x] + acetyl-CoA[x]
Left to rightBalancedEC 2.3.1.16Human-GEM MAR01211