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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

51–100 of 18,558 reactions from Rhea

butanoate + NAD(+) = (2E)-2-butenoate + NADH + H(+)
Direction not assertedBalancedRhea 10200
dimethylamine + oxidized [electron-transfer flavoprotein] + H2O + H(+) = methylamine + reduced [electron-transfer flavoprotein] + formaldehyde
Direction not assertedBalance undeterminableRhea 10204
an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = an N-terminal L-arginyl-L-aminoacyl-[protein] + tRNA(Arg) + H(+)
Left to rightBalance undeterminableRhea 10208
5-aminopentanoate + 2-oxoglutarate = 5-oxopentanoate + L-glutamate
Direction not assertedBalancedRhea 10212
[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)
Left to rightBalance undeterminableRhea 10216
tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)
Left to rightBalancedRhea 10220

pyridoxal + ATP = pyridoxal 5'-phosphate + ADP + H(+)

Left to rightBalancedRhea 10224

citrate = cis-aconitate + H2O

Direction not assertedBalancedRhea 10228

5,6-dihydrouridine 5'-phosphate + diphosphate = 5,6-dihydrouracil + 5-phospho-alpha-D-ribose 1-diphosphate

Direction not assertedBalancedRhea 10232

trans-2-coumarate + UDP-alpha-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + UDP + H(+)

Direction not assertedBalancedRhea 10236

a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 10240

4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)

Direction not assertedBalancedRhea 10244

dUTP + H2O = dUMP + diphosphate + H(+)

Direction not assertedBalancedRhea 10248

O-phospho-L-serine + hydrogen sulfide + H(+) = L-cysteine + phosphate

Direction not assertedBalancedRhea 10252

[(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O = [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + n phosphate + 2n H(+)

Direction not assertedBalance undeterminableRhea 10256

Mg(2+)(out) + ATP + H2O = Mg(2+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 10260

alpha-D-glucose = beta-D-glucose

Direction not assertedBalancedRhea 10264

2-dehydro-3-deoxy-D-glucarate = 2-hydroxy-3-oxopropanoate + pyruvate

Direction not assertedBalancedRhea 10268

a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 10272

5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP

Left to rightBalancedRhea 10276

1,7-dimethylxanthine + S-adenosyl-L-methionine = caffeine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 10280

L-leucine = (3R)-beta-leucine

Direction not assertedBalancedRhea 10284

L-rhamnono-1,4-lactone + H2O = L-rhamnonate + H(+)

Direction not assertedBalancedRhea 10288

D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)

Direction not assertedBalancedRhea 10292

D-glyceraldehyde 3-phosphate + phosphate + NADP(+) = (2R)-3-phospho-glyceroyl phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 10296

D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)

ReversibleBalancedRhea 10300

a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-[ACP] = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + holo-[ACP]

Direction not assertedBalance undeterminableRhea 10304

terephthalate + NADH + O2 + H(+) = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)

Direction not assertedBalancedRhea 10312

thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2

Direction not assertedBalancedRhea 10316

trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O

Direction not assertedBalancedRhea 10320

an L-glycol + NADP(+) = a 2-hydroxycarbonyl + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 10324

an L-glycol + NAD(+) = a 2-hydroxycarbonyl + NADH + H(+)

Direction not assertedBalance undeterminableRhea 10328

a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalance undeterminableRhea 10332

citrate = D-threo-isocitrate

Direction not assertedBalancedRhea 10336

(2E,6E)-farnesyl diphosphate = (-)-vetispiradiene + diphosphate

Direction not assertedBalancedRhea 10340

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalance undeterminableRhea 10344

5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 10348

an N-acetylarylalkylamine + H2O = an aralkylamine + acetate

Direction not assertedBalance undeterminableRhea 10352

3alpha-hydroxy-5beta-androstan-17-one + NAD(+) = 5beta-androstane-3,17-dione + NADH + H(+)

Direction not assertedBalancedRhea 10356

3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl)propanoate + H(+)

Direction not assertedBalancedRhea 10360

dodecanoyl-CoA + 2-oxoglutarate + H2O = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+)

Direction not assertedBalancedRhea 10364

dTDP-4-amino-4,6-dideoxy-alpha-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate

Direction not assertedBalancedRhea 10368

phenylglyoxylate + NAD(+) + CoA = benzoyl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 10372

Cu(2+)(in) + ATP + H2O = Cu(2+)(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 10376

orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate

Right to leftBalancedRhea 10380

cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate = beta-cyclopiazonate + diphosphate

Direction not assertedBalancedRhea 10384

oxaloacetate + GTP = phosphoenolpyruvate + GDP + CO2

ReversibleBalancedRhea 10388

(E)-cinnamyl alcohol + NADP(+) = (E)-cinnamaldehyde + NADPH + H(+)

Direction not assertedBalancedRhea 10392

an L-alpha-amino acid + NAD(+) + H2O = a 2-oxocarboxylate + NH4(+) + NADH + H(+)

Direction not assertedBalance undeterminableRhea 10396

L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine

Direction not assertedBalancedRhea 10400

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