Loading the page.
Subsystem: Xenobiotics metabolism Remove
51–100 of 158 reactions in Xenobiotics metabolism
(1S,2R)-naphthalene 1,2-oxide[c] = 1-naphthol[c]
Left to rightBalancedHuman-GEM MAR07015
(1S,2R)-naphthalene 1,2-oxide[c] = 2-naphthol[c]
Left to rightBalancedHuman-GEM MAR07016
aflatoxin B1[c] + H+[c] + NADPH[c] + O2[c] = aflatoxin Q1[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07017
aflatoxin B1[c] + H+[c] + NADPH[c] + O2[c] = aflatoxin M1[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07018
aflatoxin M1[c] + H+[c] + NADPH[c] + O2[c] = aflatoxin M1-8,9-epoxide[c] + H2O[c] + NADP+[c]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR07019
aflatoxin B1[c] + H+[c] + NADPH[c] + O2[c] = aflatoxin B1-endo-8,9-epoxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07020
aflatoxin B1[c] + H+[c] + NADPH[c] + O2[c] = aflatoxin B1-exo-8,9-epoxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07021
aflatoxin B1-exo-8,9-epoxide[c] + GSH[c] + H+[c] = aflatoxin B1-exo-8,9-epoxide-GSH[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07022
aflatoxin B1-exo-8,9-epoxide[c] + H2O[c] = aflatoxin B1 diol[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07023
aflatoxin B1 diol[c] = aflatoxin B1 dialdehyde[c] + H+[c]
Left to rightBalancedHuman-GEM MAR07024
aflatoxin B1 dialdehyde[c] + 2 H+[c] = 1,2,3,4-tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal[c]
Left to rightUnbalancedEC 1.1.1.11Human-GEM MAR07025
1,2,3,4-tetrahydro-alpha,7-dihydroxy-beta-(hydroxymethyl)-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-propanal[c] + 3 H+[c] = 6-[2,3-dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione[c]
Left to rightUnbalancedEC 1.1.1.11Human-GEM MAR07026
aflatoxin B1 dialdehyde[c] + 2 H+[c] = alpha-(1,2-dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde[c]
Left to rightUnbalancedEC 1.1.1.11Human-GEM MAR07027
alpha-(1,2-dihydroxyethyl)-1,2,3,4-tetrahydro-7-hydroxy-9-methoxy-3,4-dioxocyclopenta[c][1]benzopyran-6-acetaldehyde[c] + 3 H+[c] = 6-[2,3-dihydroxy-1-(hydroxymethyl)propyl]-1,2-dihydro-7-hydroxy-9-methoxy-cyclopenta[c][1]benzopyran-3,4-dione[c]
Left to rightUnbalancedEC 1.1.1.11Human-GEM MAR07028
GSH[c] + trichloroethene[c] = hydrochloride[c] + S-(1,2-dichlorovinyl)glutathione[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07029
H+[c] + NADPH[c] + O2[c] + trichloroethene[c] = H2O[c] + NADP+[c] + TAG epoxide[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07030
TAG epoxide[c] = dichloroacetyl chloride[c]
Left to rightBalancedHuman-GEM MAR07031
dichloroacetyl chloride[c] + 2 NADPH[c] + O2[c] = chloride[c] + dichloroacetate[c] + H2O[c] + 2 NADP+[c]
Left to rightBalancedHuman-GEM MAR07032
H+[c] + NADPH[c] + O2[c] + trichloroethene[c] = chloral[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07033
chloral[c] + H2O[c] = chloral hydrate[c]
Left to rightBalancedHuman-GEM MAR07034
chloral hydrate[c] + NAD+[c] = 2 H+[c] + NADH[c] + trichloroacetate[c]
Left to rightBalancedEC 1.2.1.5Human-GEM MAR07035
H+[c] + 2 NADPH[c] + 2 O2[c] + trichloroethanol[c] = 3 H2O[c] + 2 NADP+[c] + trichloroacetate[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07036
NADPH[c] + trichloroacetate[c] = chloride[c] + dichloroacetate[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR07037
chloral hydrate[c] + H+[c] + NADH[c] = H2O[c] + NAD+[c] + trichloroethanol[c]
Left to rightBalancedEC 1.1.1.1Human-GEM MAR07038
trichloroethanol[c] + UDP-glucuronate[c] = H+[c] + trichloroethanol glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07039
bromobenzene[c] + H+[c] + NADPH[c] + O2[c] = bromobenzene-3,4-oxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07040
bromobenzene-3,4-oxide[c] + GSH[c] + H+[c] = 3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07041
bromobenzene-3,4-oxide[c] + H2O[c] = bromobenzene-3,4-dihydrodiol[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07042
bromobenzene-3,4-oxide[c] = 4-bromophenol[c]
Left to rightBalancedHuman-GEM MAR07043
4-bromophenol[c] + H+[c] + NADPH[c] + O2[c] = 4-bromophenol-2,3-epoxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07044
4-bromophenol-2,3-epoxide[c] = 4-bromocatechol[c]
Left to rightBalancedHuman-GEM MAR07045
4-bromocatechol[c] = 4-bromo-3,5-cyclohexadiene-1,2-dione[c] + 2 H+[c]
Left to rightUnbalancedHuman-GEM MAR07046
bromobenzene-3,4-dihydrodiol[c] = 4-bromocatechol[c] + 2 H+[c]
Left to rightUnbalancedHuman-GEM MAR07047
bromobenzene[c] + H+[c] + NADPH[c] + O2[c] = bromobenzene-2,3-oxide[c] + H2O[c] + NADP+[c]
ReversibleBalancedEC 1.14.14.1Human-GEM MAR07048
2-bromophenol[c] = bromobenzene-2,3-oxide[c]
ReversibleBalancedHuman-GEM MAR07049
bromobenzene-2,3-oxide[c] + GSH[c] + H+[c] = 2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07050
bromobenzene-2,3-oxide[c] + H2O[c] = bromobenzene-2,3-dihydrodiol[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07051
7,12-dimethylbenz[a]anthracene[c] + H+[c] + NADPH[c] + O2[c] = 1a,11b-dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07052
7,12-dimethylbenz[a]anthracene[c] + H+[c] + NADPH[c] + O2[c] = 7-hydroxymethyl-12-methylbenz[a]anthracene[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07053
7,12-dimethylbenz[a]anthracene[c] + H+[c] + NADPH[c] + O2[c] = 7,12-dimethylbenz[a]anthracene 5,6-oxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07054
1a,11b-dihydro-4,9-dimethylbenz[a]anthra[3,4-b]oxirene[c] + H2O[c] = trans-3,4-dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07055
H+[c] + NADPH[c] + O2[c] + trans-3,4-dihydro-3,4-dihydroxy-7,12-dimethylbenz[a]anthracene[c] = (1aalpha,2beta,3alpha,11calpha)-1a,2,3,11c-tetrahydro-6,11-dimethylbenzo[6,7]phenanthro[3,4-b]oxirene-2,3-diol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07056
7-hydroxymethyl-12-methylbenz[a]anthracene[c] + PAPS[c] = 7-hydroxymethyl-12-methylbenz[a]anthracene sulfate[c] + PAP[c]
Left to rightBalancedEC 2.8.2.14Human-GEM MAR07057
7,12-dimethylbenz[a]anthracene 5,6-oxide[c] + H2O[c] = trans-5,6-dihydro-5,6-dihydroxy-7,12-dimethylbenz[a]anthracene[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07058
4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone[c] + H+[c] + NADPH[c] = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.146, 1.1.1.184, 1.3.1.20Human-GEM MAR07059
4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone[c] + H+[c] + NADPH[c] + O2[c] = 4-[(hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07060
4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone[c] + H+[c] + NADPH[c] + O2[c] = 4-hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07061
4-(n-nitrosomethylamino)-1-(3-pyridyl)-1-butanone[c] + H+[c] + NADPH[c] + O2[c] = 4-(methylnitrosamino)-1-(1-oxido-3-pyridinyl)-1-butanone[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR07062
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + H+[c] + NADPH[c] + O2[c] = 1-(methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07063
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + H+[c] + NADPH[c] + O2[c] = alpha-[3-[(hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07064