Reactions

Reactions

51–53 of 53 reactions in Valine, leucine, and isoleucine metabolism

• branched chain keto acid dehydrogenase E1 (3-methyl-2-oxobutyrate)

  3-methyl-2-oxobutyrate[m] + H+[m] + thiamin-PP[m] = CO2[m] + 2-(2-methyl-1-hydroxypropyl)thiamine diphosphate[m]

  → Left to rightBalance undeterminableEC 1.2.4.4Human-GEM MAR20174

• branched chain keto acid dehydrogenase E1 (2-oxo-3-methylvalerate)

  2-oxo-3-methylvalerate[m] + H+[m] + thiamin-PP[m] = CO2[m] + 2-(2-methyl-1-hydroxybutyl)thiamine diphosphate[m]

  → Left to rightBalance undeterminableEC 1.2.4.4Human-GEM MAR20175

• branched chain keto acid dehydrogenase E1 (4-methyl-2-oxopentanoate)

  4-methyl-2-oxopentanoate[m] + H+[m] + thiamin-PP[m] = CO2[m] + 2-(3-methyl-1-hydroxybutyl)thiamine diphosphate[m]

  → Left to rightBalance undeterminableEC 1.2.4.4Human-GEM MAR20176