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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,851–9,900 of 18,558 reactions from Rhea

(25S)-3-oxocholest-4-en-26-al + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = (25S)-3-oxocholest-4-en-26-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 51572
phloretin + UDP-alpha-D-glucose = phlorizin + UDP + H(+)
Direction not assertedBalancedRhea 51576
a fatty acid(out) + ATP(in) + CoA(in) + H(+)(out) = a fatty acyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)
Direction not assertedBalance undeterminableTransportRhea 51580
4-(trimethylamino)butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]
Direction not assertedBalance undeterminableRhea 51584
isopyridoxal + NAD(+) = 5-pyridoxolactone + NADH + H(+)
Direction not assertedBalancedRhea 51588
toluene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = benzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not asserted

Balance undeterminable

Rhea 51592

p-xylene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 4-methylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51596

m-xylene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 3-methylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51600

p-cymene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 4-isopropylbenzyl alcohol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51604

(R)-2-hydroxyglutarate + pyruvate = (R)-lactate + 2-oxoglutarate

Direction not assertedBalancedRhea 51608

(R)-2-hydroxyglutarate + oxaloacetate = (R)-malate + 2-oxoglutarate

Direction not assertedBalancedRhea 51612

formate + ATP + H(+) = dATP + CO2 + H2O

Direction not assertedBalancedRhea 51616

CTP + formate + H(+) = dCTP + CO2 + H2O

Direction not assertedBalancedRhea 51620

formate + GTP + H(+) = dGTP + CO2 + H2O

Direction not assertedBalancedRhea 51624

UTP + formate + H(+) = dUTP + CO2 + H2O

Direction not assertedBalancedRhea 51628

all-trans-(4S)-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-(4S,16)-dihydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51632

selenite + a quinone + H2O = selenate + a quinol

Direction not assertedBalance undeterminableRhea 51636

(9Z,12Z)-octadecadienoate + O2 = (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate

Direction not assertedBalancedRhea 51640

cholesterol + NADH + O2 + H(+) = 7-dehydrocholesterol + NAD(+) + 2 H2O

Direction not assertedBalancedRhea 51644

N(6)-acetyl-L-lysyl-[protein] + O2 + H2O = acetamide + (S)-2-amino-6-oxohexanoyl-[protein] + H2O2

Direction not assertedBalance undeterminableRhea 51648

D-mannonate + NAD(+) = keto-D-tagaturonate + NADH + H(+)

Direction not assertedBalancedRhea 51652

keto-D-tagaturonate = keto-D-fructuronate

Direction not assertedBalancedRhea 51656

an N-(1,2-saturated acyl)sphinganine + NADPH + O2 + H(+) = an N-(2-hydroxyacyl)-sphinganine + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 51660

D-5-phenylhydantoin + H2O = N-carbamoyl-D-phenylglycine + H(+)

Direction not assertedBalancedRhea 51664

mevastatin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = pravastatin lactone + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 51668

glyoxal + H2O = glycolate + H(+)

Direction not assertedBalancedRhea 51672

[protein]-disulfide + hydrogen sulfide + 2 A + 3 H2O = [protein]-dithiol + sulfite + 2 AH2 + H(+)

Direction not assertedBalance undeterminableRhea 51676

(2E,6E)-farnesol + CTP = (2E,6E)-farnesyl phosphate + CDP + H(+)

Direction not assertedBalancedRhea 51680

(2E,6E)-farnesyl phosphate + CTP = CDP + (2E,6E)-farnesyl diphosphate

Direction not assertedBalancedRhea 51684

galactitol + NAD(+) = keto-L-tagatose + NADH + H(+)

Direction not assertedBalancedRhea 51688

prephenate + S-adenosyl-L-methionine = carboxy-S-adenosyl-L-methionine + 3-phenylpyruvate + H2O

Direction not assertedBalancedRhea 51692

desmethylxanthohumol + S-adenosyl-L-methionine = xanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51696

xanthogalenol + S-adenosyl-L-methionine = 4'-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51700

xanthohumol + S-adenosyl-L-methionine = 4-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51704

D-altritol + NAD(+) = keto-D-tagatose + NADH + H(+)

Direction not assertedBalancedRhea 51708

keto-D-tagatose 6-phosphate = keto-D-fructose 6-phosphate

Direction not assertedBalancedRhea 51712

hexadecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = hexadecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51716

octadecanoate(out) + ATP(in) + CoA(in) + H(+)(out) = octadecanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 51720

P(1),P(6)-bis(5'-adenosyl) hexaphosphate + H2O = adenosine 5'-tetraphosphate + ADP + 2 H(+)

Direction not assertedBalancedRhea 51724

dihydroxyacetone phosphate + H2O = dihydroxyacetone + phosphate

Direction not assertedBalancedRhea 51728

glandicoline B + S-adenosyl-L-methionine = meleagrin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51732

L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 51736

lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 51740

lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 1-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 51744

lipid A + 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate = 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate

Direction not assertedBalance undeterminableRhea 51748

a 2-acylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4-prenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51752

a 2-acyl-4-prenylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4,6-diprenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51756

a 2-acyl-4,6-diprenylphloroglucinol + dimethylallyl diphosphate = a 2-acyl-4,6,6-triprenylphloroglucinol + diphosphate

Direction not assertedBalance undeterminableRhea 51760

phlorisovalerophenone + dimethylallyl diphosphate = 4-prenylphlorisovalerophenone + diphosphate

Direction not assertedBalancedRhea 51764

2-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one + dimethylallyl diphosphate = 4-prenylphlormethylbutanophenone + diphosphate

Direction not assertedBalancedRhea 51768

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