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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,801–9,850 of 18,558 reactions from Rhea

(9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)
Left to rightBalancedRhea 51372
dopamine + hexadecanoyl-CoA = N-hexadecanoyl-dopamine + CoA + H(+)
Direction not assertedBalancedRhea 51376
dopamine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecanoyl)-dopamine + CoA + H(+)
Direction not assertedBalancedRhea 51380
serotonin + hexadecanoyl-CoA = N-hexadecanoyl-serotonin + CoA + H(+)
Direction not assertedBalancedRhea 51384
dopamine + acetyl-CoA = N-acetyldopamine + CoA + H(+)
Direction not assertedBalancedRhea 51388
serotonin + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-serotonin + CoA + H(+)
Direction not assertedBalancedRhea 51392
serotonin + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + CoA + H(+)

Direction not assertedBalancedRhea 51396

serotonin + octadecanoyl-CoA = N-octadecanoyl-serotonin + CoA + H(+)

Direction not assertedBalancedRhea 51400

L-arginine + O2 + H2O = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)

Left to rightBalancedRhea 51404

1,2-dihexadecanoyl-sn-glycero-3-phospho-(N-hexadecanoyl)-ethanolamine + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)

Direction not assertedBalancedRhea 51408

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = (8R)-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate

Direction not assertedBalancedRhea 51412

a (2S,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)

Direction not assertedBalance undeterminableRhea 51416

a (2S,3S)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)

Direction not assertedBalance undeterminableRhea 51420

a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)

Direction not assertedBalance undeterminableRhea 51424

aminomethylphosphonate + acetyl-CoA = 2-N-acetamidomethylphosphonate + CoA

Direction not assertedBalancedRhea 51428

(S)-1-aminoethylphosphonate + acetyl-CoA = [(1S)-1-acetamidoethyl]phosphonate + CoA

Direction not assertedBalancedRhea 51432

D-alanine + acetyl-CoA = (2R)-2-amino-4-oxopentanoate + CoA

Direction not assertedBalancedRhea 51436

(9Z,12Z,15Z)-octadecatrienoate + O2 = (11S)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51440

L-leucine + (5Z,8Z,11Z,14Z)-eicosatetraenoate = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine + H2O

Direction not assertedBalancedRhea 51444

chenodeoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = alpha-muricholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51448

ursodeoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = beta-muricholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51452

N-(9Z-octadecenoyl)-L-isoleucine + H2O = L-isoleucine + (9Z)-octadecenoate

Direction not assertedBalancedRhea 51456

N-(9Z-octadecenoyl)-L-glutamate + H2O = (9Z)-octadecenoate + L-glutamate

Direction not assertedBalancedRhea 51460

deoxycholate + reduced [NADPH--hemoprotein reductase] + O2 = 1beta-hydroxydeoxycholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51464

(R)-lactate + a quinone = a quinol + pyruvate

Direction not assertedBalance undeterminableRhea 51468

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51472

a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O

Direction not assertedBalance undeterminableRhea 51476

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51480

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51484

archaetidylserine + H(+) = archaetidylethanolamine + CO2

Direction not assertedBalancedRhea 51488

all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-(4S)-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51492

a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 51496

N-acetyl-D-muramate + ATP = N-acetyl-D-muramate 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 51500

a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose = a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + UDP + H(+)

Direction not assertedBalance undeterminableRhea 51504

L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2

Direction not assertedBalancedRhea 51508

oxamate + H2O = oxalate + NH4(+)

Direction not assertedBalancedRhea 51512

(R)-reticuline + S-adenosyl-L-methionine = (R)-tembetarine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51516

(S)-reticuline + S-adenosyl-L-methionine = (S)-tembetarine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51520

(S)-corytuberine + S-adenosyl-L-methionine = magnoflorine + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 51524

vanillate + H(+) = guaiacol + CO2

Direction not assertedBalancedRhea 51528

urate + NADPH + O2 + H(+) = 5-hydroxyisourate + NADP(+) + H2O

Direction not assertedBalancedRhea 51532

L-tyrosyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = O-(N-acetyl-alpha-D-glucosaminyl)-L-tyrosyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 51536

(S)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 = (S)-corytuberine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 51540

D-ribulose = D-xylulose

Direction not assertedBalancedRhea 51544

(S)-tetrahydropapaverine + S-adenosyl-L-methionine = (S)-N-methyltetrahydropapaverine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51548

D-sorbitol + NADP(+) = L-xylo-3-hexulose + NADPH + H(+)

Direction not assertedBalancedRhea 51552

(S)-glaucine + S-adenosyl-L-methionine = (S)-N-methylglaucine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51556

(S)-bulbocapnine + S-adenosyl-L-methionine = (S)-N-methylbulbocapnine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51560

cholest-4-en-3-one + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = (25S)-3-oxocholest-4-en-26-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O

Direction not assertedBalance undeterminableRhea 51564

(25S)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25S)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O

Direction not assertedBalance undeterminableRhea 51568

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