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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,751–9,800 of 18,558 reactions from Rhea

(R)-adrenaline + O2 + H2O = (R)-3,4-dihydroxymandelaldehyde + methylamine + H2O2
Direction not assertedBalancedRhea 51168
cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(62) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 51172
cytidine(48) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(48) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 51176
cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(49) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 51180
1-octadecanoyl-sn-glycero-3-phosphoserine + H2O = sn-glycero-3-phospho-L-serine + octadecanoate + H(+)
Left to rightBalancedRhea 51184
superoxide + nitric oxide = peroxynitrite
Direction not assertedBalancedRhea 51188

(R)-2-hydroxyglutarate + NADP(+) = 2-oxoglutarate + NADPH + H(+)

Direction not assertedBalancedRhea 51192

serotonin(out) + chloride(out) + Na(+)(out) = serotonin(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 51196

N-retinylidene-N-retinylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+) = N-retinylidene-N-retinylphosphatidylethanolamine + H2O

Direction not assertedBalance undeterminableRhea 51200

6-trans-leukotriene B4 + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)

Left to rightBalancedRhea 51204

20-hydroxy-leukotriene B4 + NADP(+) = 12-oxo-20-hydroxy-leukotriene B4 + NADPH + H(+)

Left to rightBalancedRhea 51208

(5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)

Left to rightBalancedRhea 51212

3beta-hydroxyandrost-5-en-17-one + 3'-phosphoadenylyl sulfate = dehydroepiandrosterone 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 51216

1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)

Left to rightBalancedRhea 51220

S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 51224

17alpha-ethynylestradiol + 3'-phosphoadenylyl sulfate = 17alpha-ethynylestradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 51228

2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin D2

Left to rightBalancedRhea 51232

oxidized coenzyme F420-(gamma-L-Glu)(n) + GTP + L-glutamate = oxidized coenzyme F420-(gamma-L-Glu)(n+1) + GDP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 51236

(9Z,12Z)-octadecadienoate + O2 = (13R)-hydroperoxy-(9Z,11E)-octadecadienoate

Direction not assertedBalancedRhea 51240

(9Z,12Z,15Z)-octadecatrienoate + O2 = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51244

(9Z,12Z,15Z)-octadecatrienoate + O2 = (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51248

(9Z,12Z,15Z)-octadecatrienoate + O2 = (11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51252

(9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate

Direction not assertedBalancedRhea 51256

4'-O-methylnorbelladine + reduced [NADPH--hemoprotein reductase] + O2 = (10bR,4aS)-noroxomaritidine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 51260

4'-O-methylnorbelladine + reduced [NADPH--hemoprotein reductase] + O2 = (10bS,4aR)-noroxomaritidine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 51264

norbelladine + S-adenosyl-L-methionine = 4'-O-methylnorbelladine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51268

(9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)

Left to rightBalancedRhea 51272

(11S)-hydroperoxy-(9Z,12Z)-octadecadienoate = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate

Direction not assertedBalancedRhea 51276

(13R)-hydroperoxy-(9Z,11E)-octadecadienoate = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate

Direction not assertedBalancedRhea 51280

(11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate = (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51284

(11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51288

L-methionyl-[protein] + a quinone + H2O = L-methionyl-(S)-S-oxide-[protein] + a quinol

Direction not assertedBalance undeterminableRhea 51292

L-methionyl-[protein] + a quinone + H2O = L-methionyl-(R)-S-oxide-[protein] + a quinol

Direction not assertedBalance undeterminableRhea 51296

L-phenylalanine + (9Z)-octadecenoate = N-(9Z-octadecenoyl)-L-phenylalanine + H2O

ReversibleBalancedRhea 51300

(11S)-hydroperoxy-(9Z,12Z)-octadecadienoate = (13R)-hydroperoxy-(9Z,11E)-octadecadienoate

Direction not assertedBalancedRhea 51304

L-methionyl-[F-actin] + NADPH + O2 + H(+) = L-methionyl-(R)-S-oxide-[F-actin] + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 51308

(5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine + H2O

ReversibleBalancedRhea 51312

(9Z)-octadecenoate + glycine = N-(9Z-octadecenoyl)glycine + H2O

Right to leftBalancedRhea 51316

(8Z,11Z,14Z)-eicosatrienoate + O2 = (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate

Direction not assertedBalancedRhea 51324

(8Z,11Z,14Z)-eicosatrienoate + O2 = 10-hydroperoxy-(8Z,11Z,14Z)-eicosatrienoate

Direction not assertedBalancedRhea 51328

(8Z,11Z,14Z)-eicosatrienoate + O2 = 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate

Direction not assertedBalancedRhea 51332

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate

Direction not assertedBalancedRhea 51336

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate

Direction not assertedBalancedRhea 51340

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8,9-epoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O

Direction not assertedBalancedRhea 51344

7 malonyl-CoA + acetyl-CoA + 10 AH2 + 5 S-adenosyl-L-methionine + 2 H(+) = dehydroprobetaenone I + 10 A + 5 S-adenosyl-L-homocysteine + 7 CO2 + 8 CoA + 6 H2O

Direction not assertedBalancedRhea 51348

N-(9Z-octadecenoyl)-L-serine + H2O = L-serine + (9Z)-octadecenoate

Left to rightBalancedRhea 51352

N-(9Z-octadecenoyl)-L-glutamine + H2O = L-glutamine + (9Z)-octadecenoate

Left to rightBalancedRhea 51356

N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

ReversibleBalancedRhea 51360

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)

Left to rightBalancedRhea 51364

octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)

Left to rightBalancedRhea 51368

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