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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,701–9,750 of 18,558 reactions from Rhea

adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) + NH4(+)
Direction not assertedBalancedRhea 50968
(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate
Direction not assertedBalancedRhea 50972
prostaglandin D2(out) = prostaglandin D2(in)
Direction not assertedBalancedTransportRhea 50976
prostaglandin E1(out) = prostaglandin E1(in)
Left to rightBalancedTransportRhea 50980
prostaglandin E2(out) = prostaglandin E2(in)
Left to rightBalancedTransportRhea 50984
prostaglandin F2alpha(out) = prostaglandin F2alpha(in)
Left to rightBalancedTransportRhea 50988
thromboxane B2(out) = thromboxane B2(in)

Direction not assertedBalancedTransportRhea 50992

L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 50996

[fructose-bisphosphate aldolase]-L-lysine + 3 S-adenosyl-L-methionine = [fructose-bisphosphate aldolase]-N(6),N(6),N(6)-trimethyl-L-lysine + 3 S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 51000

2 Fe(III)-[cytochrome cL] + a primary alcohol = 2 Fe(II)-[cytochrome cL] + an aldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 51004

2 Fe(III)-[cytochrome cL] + methanol = 2 Fe(II)-[cytochrome cL] + formaldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 51008

a monoacyl-sn-glycero-3-phosphocholine + H2O = a monoacylglycerol + phosphocholine + H(+)

Direction not assertedBalance undeterminableRhea 51012

7,8-dihydroneopterin 3'-phosphate = glycolaldehyde phosphate + 6-hydroxymethyl-7,8-dihydropterin

Direction not assertedBalancedRhea 51016

a primary alcohol + 2 Fe(III)-[cytochrome c] = an aldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 51020

toluene-4-sulfonate + NADH + O2 + H(+) = 4-(hydroxymethyl)benzenesulfonate + NAD(+) + H2O

Direction not assertedBalancedRhea 51024

2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = 7-chloroindole-3-pyruvate imine dimer + 2 H2O

Direction not assertedBalancedRhea 51028

7-chloroindole-3-pyruvate imine dimer = dichlorochromopyrrolate + NH4(+) + H(+)

Direction not assertedBalancedRhea 51032

2 2-iminio-3-(indol-3-yl)propanoate + H2O2 = indole-3-pyruvate imine dimer + 2 H2O

Direction not assertedBalancedRhea 51036

indole-3-pyruvate imine dimer = chromopyrrolate + NH4(+) + H(+)

Direction not assertedBalancedRhea 51040

indole-3-pyruvate imine dimer = protodeoxyviolaceinate + NH4(+) + CO2

Direction not assertedBalancedRhea 51044

5alpha-androstan-3,17-dione + A = androst-4-ene-3,17-dione + AH2

Direction not assertedBalancedRhea 51048

5alpha-androstan-3,17-dione + A = 5alpha-androst-1-ene-3,17-dione + AH2

Direction not assertedBalancedRhea 51052

androst-4-ene-3,17-dione + A = androsta-1,4-diene-3,17-dione + AH2

Direction not assertedBalancedRhea 51056

5alpha-androst-1-ene-3,17-dione + A = androsta-1,4-diene-3,17-dione + AH2

Direction not assertedBalancedRhea 51060

lithocholate + 3'-phosphoadenylyl sulfate = lithocholate 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 51064

(2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate = (3S,5R,10R,12S,14S,15R,16R)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine

Direction not assertedBalancedRhea 51068

an aryl sulfate + a phenol = an aryl sulfate + a phenol

Direction not assertedBalance undeterminableRhea 51072

2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate = 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 51076

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51080

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51084

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51088

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51092

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51096

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51100

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51104

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51108

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51112

guanosine(6) in tRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 51116

(8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2 = (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O

Direction not assertedBalancedRhea 51120

uridine in snRNA = pseudouridine in snRNA

Direction not assertedBalancedRhea 51124

an aliphatic amine + A + H2O = an aldehyde + AH2 + NH4(+)

Direction not assertedBalance undeterminableRhea 51128

a purine 2'-deoxyribonucleoside 5'-phosphate + H2O = a purine nucleobase + 2-deoxy-D-ribose 5-phosphate

Direction not assertedBalance undeterminableRhea 51132

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate

Direction not assertedBalancedRhea 51136

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate

Direction not assertedBalancedRhea 51140

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate

Direction not assertedBalancedRhea 51144

2 oxidized [azurin] + a primary alcohol = 2 reduced [azurin] + an aldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 51148

L-cysteinyl-[sulfatase] + 2 a thiol + O2 = an organic disulfide + 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51152

tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Gln) + AMP + diphosphate

Direction not assertedBalancedRhea 51156

cytidine(60) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(60) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51160

cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(61) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51164

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