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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

9,201–9,250 of 18,558 reactions from Rhea

3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O = N-acetyl-D-glucosamine + L-seryl-[protein]
Direction not assertedBalance undeterminableRhea 48876
CO + a quinone + H2O = a quinol + CO2
Direction not assertedBalance undeterminableRhea 48880
protochlorophyllide a + NADP(+) = 3,8-divinyl protochlorophyllide a + NADPH + H(+)
Direction not assertedBalancedRhea 48884
(13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O
Left to rightBalancedRhea 48888
3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O = L-threonyl-[protein] + N-acetyl-D-glucosamine
Direction not assertedBalance undeterminableRhea 48892
protochlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] = 3,8-divinyl protochlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)
Direction not assertedBalance undeterminable

Rhea 48896

chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] = 3,8-divinyl chlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 48900

L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 48904

L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 48908

a ganglioside GD1a + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1a + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48912

a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1c + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48916

bacteriochlorophyllide g + 2 oxidized [2Fe-2S]-[ferredoxin] + ADP + phosphate = 3,8-divinyl chlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + ATP + H2O + H(+)

Direction not assertedBalance undeterminableRhea 48920

a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48924

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48928

a ganglioside GT1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b + CMP + H(+)

Direction not assertedBalance undeterminableRhea 48932

L-prolyl-[Skp1 protein] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[Skp1 protein] + succinate + CO2

Direction not assertedBalance undeterminableRhea 48936

an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid

Direction not assertedBalance undeterminableRhea 48940

bacteriochlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] + ADP + phosphate = 3-acetyl-3-devinylchlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + ATP + H2O + H(+)

Direction not assertedBalance undeterminableRhea 48944

3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] + ADP + phosphate = 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + ATP + H2O + H(+)

Direction not assertedBalance undeterminableRhea 48948

14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NADH + H(+)

Left to rightBalancedRhea 48952

[thyroglobulin]-L-tyrosine + iodide + H2O2 + H(+) = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O

Direction not assertedBalance undeterminableRhea 48956

[thyroglobulin]-3-iodo-L-tyrosine + iodide + H2O2 + H(+) = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O

Direction not assertedBalance undeterminableRhea 48960

2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-L-thyroxine + [thyroglobulin]-dehydroalanine + 2 H2O

Direction not assertedBalance undeterminableRhea 48964

[thyroglobulin]-3-iodo-L-tyrosine + [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O

Direction not assertedBalance undeterminableRhea 48968

phosphite(out) + ATP + H2O = phosphite(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 48972

5-methyl-phenazine-1-carboxylate + NADH + O2 + 2 H(+) = pyocyanin + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 48976

3,4-dichlorocatechol + O2 = (2Z,4Z)-2,3-dichloromuconate + 2 H(+)

Direction not assertedBalancedRhea 48980

(2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + glyoxylate + succinate + CO2

Direction not assertedBalancedRhea 48984

1,3,7-trimethylurate + NADH + O2 + H(+) = 1,3,7-trimethyl-5-hydroxyisourate + NAD(+) + H2O

Direction not assertedBalancedRhea 48992

3-methylcatechol + O2 = 2-hydroxy-6-oxo-2,4-heptadienoate + H(+)

Direction not assertedBalancedRhea 48996

aurachin C + NADH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD(+) + H2O

Direction not assertedBalancedRhea 49000

aurachin C + NADPH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 49004

aurachin C + NADPH + O2 + H(+) = aurachin C epoxide + NADP(+) + H2O

Direction not assertedBalancedRhea 49008

aurachin C + NADH + O2 + H(+) = aurachin C epoxide + NAD(+) + H2O

Direction not assertedBalancedRhea 49012

aurachin C epoxide = 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one

Direction not assertedBalancedRhea 49016

2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide

Direction not assertedBalancedRhea 49020

L-tryptophan + O2 = 2-iminio-3-(indol-3-yl)propanoate + H2O2

Direction not assertedBalancedRhea 49024

(-)-bursehernin + reduced [NADPH--hemoprotein reductase] + O2 = (-)-5'-demethylyatein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49028

(-)-4'-desmethyl-deoxypodophyllotoxin + reduced [NADPH--hemoprotein reductase] + O2 = 4'-demethylepipodophyllotoxin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49032

(-)-pluviatolide + S-adenosyl-L-methionine = (-)-bursehernin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49036

(-)-5'-demethylyatein + S-adenosyl-L-methionine = (-)-yatein + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 49040

protoasukamycin + NADH + O2 + H(+) = 4-hydroxyprotoasukamycin + NAD(+) + H2O

Direction not assertedBalancedRhea 49044

25-hydroxyvitamin D2 + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 1alpha,25-dihydroxyvitamin D2 + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49048

asperlicin C + NADH + O2 + H(+) = asperlicin E + NAD(+) + H2O

Direction not assertedBalancedRhea 49052

asperlicin C + NADPH + O2 + H(+) = asperlicin E + NADP(+) + H2O

Direction not assertedBalancedRhea 49056

a long-chain alkane + FMNH2 + O2 = a long chain fatty alcohol + FMN + H2O + H(+)

Direction not assertedBalance undeterminableRhea 49060

secalciferol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = calcitetrol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49064

25-hydroxy-24-oxocalciol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (1S)-1,25-dihydroxy-24-oxocalciol + 2 oxidized [adrenodoxin] + H2O

Left to rightBalance undeterminableRhea 49068

dibenzothiophene + 2 FMNH2 + 2 O2 = dibenzothiophene 5,5-dioxide + 2 FMN + 2 H2O + 2 H(+)

Direction not assertedBalancedRhea 49072

dibenzothiophene + FMNH2 + O2 = dibenzothiophene 5-oxide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 49076

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