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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,951–9,000 of 18,558 reactions from Rhea

a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate
Left to rightBalance undeterminableRhea 47852
a ganglioside GD1a (d18:1(4E)) + H2O = a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate
Left to rightBalance undeterminableRhea 47856
a ganglioside GT1b (d18:1(4E)) + H2O = a ganglioside GD1b (d18:1(4E)) + N-acetylneuraminate
Direction not assertedBalance undeterminableRhea 47860
1,2,3-trioctanoylglycerol + H2O = dioctanoylglycerol + octanoate + H(+)
Left to rightBalancedRhea 47864
di-(9Z)-octadecenoylglycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)
Left to rightBalancedRhea 47868
a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate
Left to rightBalance undeterminableRhea 47872
a ganglioside GD1b + H2O = a ganglioside GM1 + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47876

dioctanoylglycerol + H2O = octanoylglycerol + octanoate + H(+)

Direction not assertedBalancedRhea 47880

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP + H(+)

Left to rightBalance undeterminableRhea 47884

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP-beta-L-fucose = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-alpha-L-fucosyl-(1->4)-[N-acetyl-beta-D-glucosaminyl-(1->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP + H(+)

Left to rightBalance undeterminableRhea 47888

N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP-beta-L-fucose = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-alpha-L-fucosyl-(1->4)-[N-acetyl-alpha-neuraminosyl-(2->6)-N-acetyl-beta-D-glucosaminyl-(1->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + GDP + H(+)

Left to rightBalance undeterminableRhea 47892

6-sulfo-D-quinovose + NAD(+) = 6-deoxy-6-sulfo-D-glucono-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 47896

a ganglioside GM3 (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate

Left to rightBalance undeterminableRhea 47900

N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)

Left to rightBalancedRhea 47904

6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O = 6-deoxy-6-sulfo-D-gluconate + H(+)

Direction not assertedBalancedRhea 47908

6-deoxy-6-sulfo-D-gluconate = 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O

Direction not assertedBalancedRhea 47912

N-hexanoyl-(4R)-hydroxysphinganine + ATP = N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate + ADP + H(+)

Left to rightBalancedRhea 47916

ganglioside GM2 (d18:1(4E)/18:0) + H2O = ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate

Direction not assertedBalancedRhea 47920

2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate = (2S)-3-sulfolactaldehyde + pyruvate

Direction not assertedBalancedRhea 47924

(2S)-3-sulfolactaldehyde + NADP(+) + H2O = (2S)-3-sulfolactate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 47928

(2S)-3-sulfolactaldehyde + NAD(+) + H2O = (2S)-3-sulfolactate + NADH + 2 H(+)

Direction not assertedBalancedRhea 47932

4-hydroxybenzaldehyde + NADP(+) + H2O = 4-hydroxybenzoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 47936

a ganglioside GM2 (d18:1(4E)) + H2O = a ganglioside GM3 (d18:1(4E)) + N-acetyl-beta-D-galactosamine

Left to rightBalance undeterminableRhea 47940

(2E)-geranyl diphosphate + H2O = (2E)-geranyl phosphate + phosphate + H(+)

Left to rightBalancedRhea 47944

thiamine phosphate + H2O = thiamine + phosphate

Direction not assertedBalancedRhea 47948

[prokaryotic ubiquitin-like protein]-C-terminal-L-glutamine + H2O = [prokaryotic ubiquitin-like protein]-C-terminal-L-glutamate + NH4(+)

Direction not assertedBalance undeterminableRhea 47952

3-maleylpyruvate + H2O = maleate + pyruvate + H(+)

Direction not assertedBalancedRhea 47956

N(tele)-phospho-L-histidyl-[protein] + H2O = L-histidyl-[protein] + phosphate

Direction not assertedBalance undeterminableRhea 47960

N(pros)-phospho-L-histidyl-[protein] + H2O = L-histidyl-[protein] + phosphate

Direction not assertedBalance undeterminableRhea 47964

a ganglioside GM2 + H2O = a ganglioside GM3 + N-acetyl-beta-D-galactosamine

Left to rightBalance undeterminableRhea 47968

dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O

Direction not assertedBalancedRhea 47972

dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O

Direction not assertedBalancedRhea 47976

dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose = dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose

Direction not assertedBalancedRhea 47980

presqualene diphosphate + H2O = hydroxysqualene + diphosphate

Direction not assertedBalancedRhea 47984

2-dehydro-3-deoxy-L-galactonate + NAD(+) = 3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H(+)

Direction not assertedBalancedRhea 47988

NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)

Direction not assertedBalancedTransportRhea 47992

1,6-dihydro-beta-NAD + O2 + H(+) = H2O2 + NAD(+)

Direction not assertedBalancedRhea 47996

1,6-dihydro-beta-NADP + O2 + H(+) = H2O2 + NADP(+)

Direction not assertedBalancedRhea 48000

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol + H2O2 = 3,4-dimethoxybenzaldehyde + guaiacol + glycolaldehyde + H2O

Direction not assertedBalancedRhea 48004

2-hydroxybenzoyl-CoA + NADH + O2 + H(+) = 2,5-dihydroxybenzoyl-CoA + NAD(+) + H2O

Direction not assertedBalancedRhea 48008

4-methyl-5-nitrocatechol + NADPH + O2 = 2-hydroxy-5-methylquinone + nitrite + NADP(+) + H2O + H(+)

Direction not assertedBalancedRhea 48012

4-methyl-5-nitrocatechol + NADH + O2 = 2-hydroxy-5-methylquinone + nitrite + NAD(+) + H2O + H(+)

Direction not assertedBalancedRhea 48016

a globoside Gb3Cer + H2O = a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + D-galactose

Left to rightBalance undeterminableRhea 48020

1,2,3-tripropanoylglycerol + H2O = dipropanoylglycerol + propanoate + H(+)

Left to rightBalancedRhea 48024

triacetin + H2O = diacetylglycerol + acetate + H(+)

Direction not assertedBalancedRhea 48028

a globoside Gb4Cer (d18:1(4E)) + H2O = a globoside Gb3Cer (d18:1(4E)) + N-acetyl-beta-D-galactosamine

Direction not assertedBalance undeterminableRhea 48036

a globoside Gb4Cer + H2O = a globoside Gb3Cer + N-acetyl-beta-D-galactosamine

Direction not assertedBalance undeterminableRhea 48040

ganglioside GM1 (d18:1(4E)/18:0) + H2O = ganglioside GM2 (d18:1(4E)/18:0) + D-galactose

Direction not assertedBalancedRhea 48044

a ganglioside GM1 (d18:1(4E)) + H2O = a ganglioside GM2 (d18:1(4E)) + D-galactose

Direction not assertedBalance undeterminableRhea 48048

dermatan + n 3'-phosphoadenylyl sulfate = dermatan 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)

Direction not assertedBalance undeterminableRhea 48052

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