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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,701–8,750 of 18,558 reactions from Rhea

4alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O
Direction not assertedBalance undeterminableRhea 46840
4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O
Direction not assertedBalance undeterminableRhea 46844
4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NADP(+) = 5alpha-cholest-8-en-3-one + CO2 + NADPH
Left to rightBalancedRhea 46848
5alpha-cholest-8-en-3-one + NADPH + H(+) = 5alpha-cholest-8-en-3beta-ol + NADP(+)
Left to rightBalancedRhea 46852
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + H(+) = 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + NADP(+)
Direction not assertedBalancedRhea 46856
3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 46860

lipid A (E. coli) + a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine = hepta-acyl lipid A (E. coli) + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 46864

lipid IVA (E. coli) + a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine = lipid IVB (E. coli) + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 46868

lipid IIA + a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine = lipid IIB + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 46872

[(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate = [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)

Direction not assertedBalance undeterminableRhea 46876

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = a 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 46880

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 46884

3-deoxy-alpha-D-manno-oct-2-ulosonate + O2 = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + H2O2

Direction not assertedBalancedRhea 46888

8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate

Direction not assertedBalancedRhea 46892

lipid A (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A hexaacyl 1-(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 46896

lipid A (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 4'-(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 46900

lipid A hexaacyl 1-(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 1,4'-bis(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 46904

alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 46908

juvenile hormone III + H2O = juvenile hormone III carboxylate + methanol + H(+)

Direction not assertedBalancedRhea 46912

juvenile hormone I + H2O = juvenile hormone I carboxylate + methanol + H(+)

Direction not assertedBalancedRhea 46916

(E)-cinnamate + H(+) = styrene + CO2

Direction not assertedBalancedRhea 46920

(R)-2-hydroxy-4-methylpentanoyl-CoA = 4-methylpent-2-enoyl-CoA + H2O

Direction not assertedBalancedRhea 46924

a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol

Direction not assertedBalance undeterminableRhea 46928

2-epi-5-epi-valiolone 7-phosphate = 5-epi-valiolone 7-phosphate

Direction not assertedBalancedRhea 46932

(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = L-2-aminoadipate + ATP + NADPH + H(+)

Direction not assertedBalancedRhea 46936

L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + AMP + diphosphate = holo-[LYS2 peptidyl-carrier protein] + L-2-aminoadipate + ATP

Direction not assertedBalance undeterminableRhea 46940

holo-[LYS2 peptidyl-carrier protein] + (S)-2-amino-6-oxohexanoate + NADP(+) = L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 46944

GTP + S-adenosyl-L-methionine = N(7)-methyl-GTP + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 46948

2 formate + 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) = 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 + NADH + H(+)

Direction not assertedBalance undeterminableRhea 46952

hydrocaffeoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) = (E)-caffeoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 NADH

Direction not assertedBalance undeterminableRhea 46956

butanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) = (2E)-butenoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 NADH

Direction not assertedBalance undeterminableRhea 46960

lactate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) = 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate + 2 NADH

Direction not assertedBalance undeterminableRhea 46964

dihydroisopentenyldehydrorhodopin + A = isopentenyldehydrorhodopin + AH2

Direction not assertedBalancedRhea 46968

dihydrobisanhydrobacterioruberin + A = bisanhydrobacterioruberin + AH2

Direction not assertedBalancedRhea 46972

(S)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2

Direction not assertedBalancedRhea 46976

(R)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2

Direction not assertedBalancedRhea 46988

6-hydroxy-N-methylmyosmine + H2O = 6-hydroxypseudooxynicotine

Direction not assertedBalancedRhea 46996

2 reduced [2Fe-2S]-[ferredoxin] + NADH + 2 NADP(+) + H(+) = 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) + 2 NADPH

Direction not assertedBalance undeterminableRhea 47000

O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate

Left to rightBalance undeterminableRhea 47004

[DsrC protein]-disulfide + hydrogen sulfide + 2 A + 3 H2O = [DsrC protein]-dithiol + sulfite + 2 AH2 + H(+)

Direction not assertedBalance undeterminableRhea 47008

[DsrC protein]-disulfide + hydrogen sulfide + H(+) = [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine

Direction not assertedBalance undeterminableRhea 47012

[DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O = [DsrC protein]-dithiol + sulfite + 2 AH2 + 2 H(+)

Direction not assertedBalance undeterminableRhea 47016

[DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O = [DsrC protein]-disulfide + sulfite + 3 AH2 + 2 H(+)

Direction not assertedBalance undeterminableRhea 47020

[DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O = [DsrC protein]-S-sulfo-L-cysteine/L-cysteine + 3 AH2 + H(+)

Direction not assertedBalance undeterminableRhea 47024

[DsrC protein]-S-sulfo-L-cysteine/L-cysteine = [DsrC protein]-disulfide + sulfite + H(+)

Direction not assertedBalance undeterminableRhea 47028

S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA + AH2 + ATP = 2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 47032

uridine in 5S rRNA = pseudouridine in 5S rRNA

Direction not assertedBalancedRhea 47036

5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP = 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+)

Left to rightBalance undeterminableRhea 47040

3-dehydrocarnitine + acetyl-CoA = N,N,N-trimethylglycyl-CoA + acetoacetate

Direction not assertedBalancedRhea 47044

shikimate + a quinone = 3-dehydroshikimate + a quinol

Direction not assertedBalance undeterminableRhea 47048

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