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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,451–8,500 of 18,558 reactions from Rhea

(3R)-3-hydroxydecanoyl-CoA + NAD(+) = 3-oxodecanoyl-CoA + NADH + H(+)
Left to rightBalancedRhea 45832
1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate
Left to rightBalancedRhea 45836
(3R)-3-hydroxydecanoyl-CoA + NADP(+) = 3-oxodecanoyl-CoA + NADPH + H(+)
Direction not assertedBalancedRhea 45840
(3R)-hydroxyoctanoyl-CoA + NADP(+) = 3-oxooctanoyl-CoA + NADPH + H(+)
Direction not assertedBalancedRhea 45844
(3R)-3-hydroxydodecanoyl-CoA + NADP(+) = 3-oxododecanoyl-CoA + NADPH + H(+)
Direction not assertedBalancedRhea 45848
Co(II)-factor III + S-adenosyl-L-methionine + H(+) = Co(II)-factor IV + S-adenosyl-L-homocysteine
Direction not assertedBalancedRhea 45852
3-hydroxytetradecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45856

12-hydroxyoctadecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(11-hydroxyheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45860

16-hydroxyhexadecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(15-hydroxypentadecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45864

9-decenoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45868

15-hydroxypentadecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45872

2-methylhexadecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45876

3-methylundecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45880

12-methyloctadecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45884

12-methyltridecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 45888

CDP-ethanolamine + an N-acylsphing-4-enine = an N-acylsphing-4-enine 1-phosphoethanolamine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 45892

CDP-ethanolamine + an N-acyl-sphingoid base = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 45896

a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA

Left to rightBalance undeterminableRhea 45900

dTDP-beta-L-vancosamine + devancoaminyl-vancomycin = epivancomycin + dTDP + H(+)

Direction not assertedBalancedRhea 45904

chloroorienticin B + dTDP-beta-L-vancosamine = chloroeremomycin + dTDP + H(+)

Direction not assertedBalancedRhea 45908

a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)

Left to rightBalance undeterminableRhea 45912

12-hydroxyoctadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45916

16-hydroxyhexadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45920

9-decenoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45924

15-hydroxypentadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45928

2-methylhexadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45932

3-methylundecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(4-methyl-2-oxododecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45936

12-methyloctadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45940

12-methyltridecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 45944

L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)

ReversibleBalance undeterminableRhea 45948

L-asparaginyl-[protein] + UDP-alpha-D-glucose = N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 45952

(9Z)-octadecenoyl-CoA(in) = (9Z)-octadecenoyl-CoA(out)

Direction not assertedBalancedTransportRhea 45956

24,25-dihydrolanosterol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Left to rightBalance undeterminableRhea 45960

5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O = 2 AMP + ATP + 2 H(+)

Direction not assertedBalancedRhea 45964

androst-4-ene-3,17-dione + NADH + O2 + H(+) = 9alpha-hydroxy-androst-4-ene-3,17-dione + NAD(+) + H2O

Direction not assertedBalancedRhea 45968

3-oxochol-4-en-22-oate + NADH + O2 + H(+) = 9alpha-hydroxy-3-oxochol-4-en-22-oate + NAD(+) + H2O

Direction not assertedBalancedRhea 45972

3-oxochola-1,4-dien-22-oate + NADH + O2 + H(+) = 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + NAD(+) + H2O

Direction not assertedBalancedRhea 45976

3-oxochol-4-en-22-oyl-CoA + NADH + O2 + H(+) = 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + NAD(+) + H2O

Direction not assertedBalancedRhea 45980

3-oxochola-1,4-dien-22-oyl-CoA + NADH + O2 + H(+) = 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + NAD(+) + H2O

Direction not assertedBalancedRhea 45984

3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMNH2 + O2 = 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMN + H2O + H(+)

Direction not assertedBalancedRhea 45988

(3R)-3-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O

Right to leftBalancedRhea 45992

a D-alpha-amino acid + a quinone + H2O = a 2-oxocarboxylate + a quinol + NH4(+)

Direction not assertedBalance undeterminableRhea 45996

tuberculosinyl diphosphate + adenosine + H(+) = 1-tuberculosinyladenosine + diphosphate

Direction not assertedBalancedRhea 46000

2-methylpropanal + NAD(+) + CoA = 2-methylpropanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 46004

pentanal + NAD(+) + CoA = pentanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 46008

(S)-malate + a quinone = a quinol + oxaloacetate

Direction not assertedBalance undeterminableRhea 46012

(20R)-20-hydroxypregn-4-en-3-one + NAD(+) = progesterone + NADH + H(+)

Direction not assertedBalancedRhea 46016

[pyruvate, water dikinase] + ADP = [pyruvate, water dikinase]-phosphate + AMP + H(+)

Direction not assertedBalance undeterminableRhea 46020

tetradecanoate + H2O2 = (3R)-hydroxytetradecanoate + H2O

Direction not assertedBalancedRhea 46024

tetradecanoate + H2O2 = (2R)-hydroxytetradecanoate + H2O

Direction not assertedBalancedRhea 46028

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