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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,251–8,300 of 18,558 reactions from Rhea

hydroxylamine + 4 Fe(III)-[cytochrome c] + H2O = 4 Fe(II)-[cytochrome c] + nitrite + 5 H(+)
Direction not assertedBalance undeterminableRhea 45032
hydroxylamine + 3 Fe(III)-[cytochrome c] = nitric oxide + 3 Fe(II)-[cytochrome c] + 3 H(+)
Direction not assertedBalance undeterminableRhea 45036
hydroxylamine + 2 Fe(III)-[cytochrome c] = nitroxyl + 2 Fe(II)-[cytochrome c] + 2 H(+)
Direction not assertedBalance undeterminableRhea 45040
nitroxyl + 2 Fe(II)-[cytochrome c] + O2 + H(+) = 2 Fe(III)-[cytochrome c] + nitrite + H2O
Direction not assertedBalance undeterminableRhea 45044
acetamide + H2O = acetate + NH4(+)
Direction not assertedBalancedRhea 45048
(2E)-butenoyl-CoA + (R)-carnitine = O-(2E)-butenoyl-(R)-carnitine + CoA
Direction not assertedBalancedRhea 45052

deoxynogalonate + O2 = nogalonate + H2O + H(+)

Direction not assertedBalancedRhea 45056

N-(9Z-octadecenoyl) ethanolamine + H2O = ethanolamine + (9Z)-octadecenoate

Left to rightBalancedRhea 45060

N-hexadecanoylethanolamine + H2O = ethanolamine + hexadecanoate

Left to rightBalancedRhea 45064

(R)-carnitine + an acyl-CoA = an O-acyl-(R)-carnitine + CoA

Direction not assertedBalance undeterminableRhea 45068

(9Z)-octadecenoyl-CoA + reduced [NADPH--hemoprotein reductase] + O2 = (9Z)-18-hydroxyoctadecenoyl-CoA + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 45072

(9Z,12Z)-octadecadienoyl-CoA + reduced [NADPH--hemoprotein reductase] + O2 = (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 45076

3-[[[(2R,3R)-3-carboxyoxiran-2-yl]carbonyl]amino]-L-alanine + L-valine + ATP = dapdiamide E + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 45080

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 7-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 45084

a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline

Left to rightBalance undeterminableRhea 45088

N-octanoylsphing-4-enine + H2O = octanoate + sphing-4-enine

Left to rightBalancedRhea 45092

(9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 45096

6-demethylmitomycin B + S-adenosyl-L-methionine = mitomycin B + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 45100

6-demethylmitomycin A + S-adenosyl-L-methionine = mitomycin A + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 45104

(+)-alpha-tocopherol + reduced [NADPH--hemoprotein reductase] + O2 = 13-hydroxy-alpha-tocopherol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 45108

gamma-tocopherol + NADPH + O2 + H(+) = 13-hydroxy-gamma-tocopherol + NADP(+) + H2O

Left to rightBalancedRhea 45112

(4R)-ipsdienol + NADP(+) = ipsdienone + NADPH + H(+)

Direction not assertedBalancedRhea 45116

(4R)-ipsdienol + NAD(+) = ipsdienone + NADH + H(+)

Direction not assertedBalancedRhea 45120

acarbose + ATP = acarbose 7(IV)-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 45124

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 45128

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Left to rightBalancedRhea 45132

2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate = 7,8-dihydroneopterin 3'-phosphate + H2O

Direction not assertedBalancedRhea 45136

4-carboxy-L-glutamyl-[protein] + 2,3-epoxyphylloquinone + H2O + H(+) = phylloquinol + L-glutamyl-[protein] + CO2 + O2

Right to leftBalance undeterminableRhea 45140

3-(methylsulfanyl)acryloyl-CoA + 2 H2O = methanethiol + acetaldehyde + CO2 + CoA

Direction not assertedBalancedRhea 45144

3-(methylsulfanyl)acryloyl-CoA + H2O = 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA

Direction not assertedBalancedRhea 45148

3-hydroxy-3-(methylsulfanyl)propanoyl-CoA = 3-oxopropanoyl-CoA + methanethiol

Direction not assertedBalancedRhea 45152

3-oxopropanoyl-CoA + H2O = 3-oxopropanoate + CoA + H(+)

Direction not assertedBalancedRhea 45156

3-oxopropanoate + H(+) = acetaldehyde + CO2

Direction not assertedBalancedRhea 45160

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)

Left to rightBalancedRhea 45164

2 (E)-sinapoyl-CoA + spermidine = N(1),N(8)-bis[(E)-sinapoyl]-spermidine + 2 CoA + 2 H(+)

Direction not assertedBalancedRhea 45168

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 45172

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 45176

2 (E)-4-coumaroyl-CoA + spermidine = N(1),N(8)-bis(coumaroyl)-spermidine + 2 CoA + 2 H(+)

Direction not assertedBalancedRhea 45180

5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+) = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + H2O + H(+)

Direction not assertedBalancedRhea 45184

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45188

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalance undeterminableRhea 45192

5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)

Direction not assertedBalance undeterminableRhea 45196

methyl-Co(III)-[corrinoid Fe-S protein] + (6S)-5,6,7,8-tetrahydrofolate = Co(I)-[corrinoid Fe-S protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalance undeterminableRhea 45200

Co(I)-[methanol-specific corrinoid protein] + methanol + H(+) = methyl-Co(III)-[methanol-specific corrinoid protein] + H2O

Direction not assertedBalance undeterminableRhea 45204

methyl-Co(III)-[methanol-specific corrinoid protein] + coenzyme M = Co(I)-[methanol-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45208

Co(I)-[corrinoid Fe-S protein] + acetyl-CoA + H(+) = methyl-Co(III)-[corrinoid Fe-S protein] + CO + CoA

Direction not assertedBalance undeterminableRhea 45212

methyl-Co(III)-[dimethylamine-specific corrinoid protein] + coenzyme M = Co(I)-[dimethylamine-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45216

methyl-Co(III)-[trimethylamine-specific corrinoid protein] + coenzyme M = Co(I)-[trimethylamine-specific corrinoid protein] + methyl-coenzyme M + H(+)

Direction not assertedBalance undeterminableRhea 45220

(3E,5Z,8Z,11Z,14Z)-eicosapentaenoyl-CoA = (2E,4E,8Z,11Z,14Z)-eicosapentaenoyl-CoA

Left to rightBalancedRhea 45224

a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA

Left to rightBalance undeterminableRhea 45228

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