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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

8,001–8,050 of 18,558 reactions from Rhea

L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O
Direction not assertedBalancedRhea 44028
9,10-epoxy-(12Z)-octadecenoate + H2O = 9,10-dihydroxy-(12Z)-octadecenoate
Left to rightBalancedRhea 44032
12,13-epoxy-(9Z)-octadecenoate + H2O = 12,13-dihydroxy-(9Z)-octadecenoate
Direction not assertedBalancedRhea 44036
14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = 14,15-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate
Left to rightBalancedRhea 44040
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = 11,12-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate
Left to rightBalancedRhea 44044
8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O = 8,9-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate
Left to rightBalancedRhea 44048
alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O-hexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44052

2-O-hexadecanoyl-alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O,3-O-dihexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44056

2-O-sulfo-alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O-sulfo-2'-O-hexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44060

octan-1-ol + hexadecanoyl-CoA = octyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44064

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 44068

1-O-alkyl-2-acyl-sn-glycerol + ATP = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 44072

pentadecanoate + ATP + CoA = pentadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44076

undecanoate + ATP + CoA = undecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44080

heptadecanoate + ATP + CoA = heptadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44084

heptanoate + ATP + CoA = heptanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44088

nonadecanoate + ATP + CoA = nonadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44092

decan-1-ol + hexadecanoyl-CoA = decyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44096

octanal + NAD(+) + H2O = octanoate + NADH + 2 H(+)

Left to rightBalancedRhea 44100

decanal + NAD(+) + H2O = decanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44104

heptanal + NAD(+) + H2O = heptanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44108

nonan-1-ol + hexadecanoyl-CoA = nonyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44112

eicosan-1-ol + hexadecanoyl-CoA = eicosyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44116

octadecan-1-ol + hexadecanoyl-CoA = octadecyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44120

tetradecan-1-ol + hexadecanoyl-CoA = tetradecyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44124

(9E)-octadecenoyl-CoA + hexadecan-1-ol = hexadecyl (9E)-octadecenoate + CoA

Direction not assertedBalancedRhea 44128

2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine + 2 H(+)

Direction not assertedBalancedRhea 44132

hexadecan-1-ol + dodecanoyl-CoA = hexadecyl dodecanoate + CoA

Direction not assertedBalancedRhea 44136

oxidized [flavodoxin] + pyruvate + CoA + 2 H(+) = reduced [flavodoxin] + acetyl-CoA + CO2

Direction not assertedBalance undeterminableRhea 44140

L-methionine + acetyl-CoA = N-acetyl-L-methionine + CoA + H(+)

Direction not assertedBalancedRhea 44144

L-lysine = D-beta-lysine

Direction not assertedBalancedRhea 44148

1D-myo-inositol 2-phosphate + H2O = myo-inositol + phosphate

Left to rightBalancedRhea 44152

1D-myo-inositol 5-phosphate + H2O = myo-inositol + phosphate

Left to rightBalancedRhea 44156

1D-myo-inositol 6-phosphate + H2O = myo-inositol + phosphate

Left to rightBalancedRhea 44160

ATP + H2O = D-ribose 5-triphosphate + adenine

Direction not assertedBalancedRhea 44164

dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O

Direction not assertedBalancedRhea 44168

tetradecanal + NAD(+) + H2O = tetradecanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44172

a 2,3-diacyl-sn-glycerol + H2O = a 3-acyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 44176

2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 44180

D-sedoheptulose 7-phosphate = 2-epi-5-epi-valiolone + phosphate

Direction not assertedBalancedRhea 44184

(9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA

Direction not assertedBalancedRhea 44188

2-methylhexadecanoate + ATP + CoA = 2-methylhexadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44192

3-methylundecanoate + ATP + CoA = 3-methylundecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44196

12-methyloctadecanoate + ATP + CoA = 12-methyloctadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44200

2-hydroxyhexadecanoate + ATP + CoA = 2-hydroxyhexadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44204

12-methyltridecanoate + ATP + CoA = 12-methyltridecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44208

3-hydroxytetradecanoate + ATP + CoA = 3-hydroxytetradecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44212

12-hydroxyoctadecanoate + ATP + CoA = 12-hydroxyoctadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44216

15-hydroxypentadecanoate + ATP + CoA = 15-hydroxypentadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44220

16-hydroxyhexadecanoate + ATP + CoA = 16-hydroxyhexadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44224

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