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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,851–7,900 of 18,558 reactions from Rhea

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)
Left to rightBalancedRhea 43416
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycerol + ATP = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)
Left to rightBalancedRhea 43420
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)
Left to rightBalancedRhea 43424
1,2-didecanoyl-sn-glycerol + ATP = 1,2-didecanoyl-sn-glycero-3-phosphate + ADP + H(+)
Left to rightBalancedRhea 43428
butan-1-ol + 2 Fe(III)-[cytochrome c] = butanal + 2 Fe(II)-[cytochrome c] + 2 H(+)
Direction not assertedBalance undeterminableRhea 43432
coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2
Direction not assertedBalancedRhea 43436

sphinganine + hexadecanoate = N-hexadecanoylsphinganine + H2O

Right to leftBalancedRhea 43440

1,2-ditetradecanoyl-sn-glycerol + ATP = 1,2-ditetradecanoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 43444

oxidized [electron-transfer flavoprotein] + hexadecanoyl-CoA + H(+) = (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 43448

hexanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-pentylpyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 43452

pentanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 43456

dodecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA

Direction not assertedBalancedRhea 43460

hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 43464

(8Z,11Z,14Z)-eicosatrienoate + O2 = (8Z,10E,14Z)-12-hydroperoxyeicosatrienoate

Left to rightBalancedRhea 43468

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate

Left to rightBalancedRhea 43472

(6Z,9Z,12Z)-octadecatrienoate + O2 = 10-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate

Left to rightBalancedRhea 43476

1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate

Left to rightBalancedRhea 43480

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 43484

7(1)-hydroxychlorophyll a + NAD(+) = chlorophyll b + NADH + H(+)

Direction not assertedBalancedRhea 43488

7(1)-hydroxychlorophyll a + NADP(+) = chlorophyll b + NADPH + H(+)

Direction not assertedBalancedRhea 43492

L-gulonate + NAD(+) = keto-D-fructuronate + NADH + H(+)

Direction not assertedBalancedRhea 43496

beta-D-glucuronate + NAD(+) = D-glucaro-1,5-lactone + NADH + H(+)

Direction not assertedBalancedRhea 43500

5-hydroxymethylfurfural + O2 = 2,5-diformylfuran + H2O2

Direction not assertedBalancedRhea 43504

2,5-diformylfuran + H2O = 2-(dihydroxymethyl)-5-formylfuran

Direction not assertedBalancedRhea 43508

2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H2O2 + H(+)

Direction not assertedBalancedRhea 43512

2-carboxy-5-formylfuran + H2O = 2-carboxy-5-(dihydroxymethyl)furan

Direction not assertedBalancedRhea 43516

2-carboxy-5-(dihydroxymethyl)furan + O2 = 2,5-dicarboxyfuran + H2O2 + H(+)

Direction not assertedBalancedRhea 43520

L-allo-threonine + NADP(+) = aminoacetone + CO2 + NADPH

Direction not assertedBalancedRhea 43524

L-serine + NAD(+) = 2-aminomalonate semialdehyde + NADH + H(+)

Direction not assertedBalancedRhea 43528

a ribonucleoside 3',5'-bisphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate

Direction not assertedBalance undeterminableRhea 43532

2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + phosphate + 2 H2O

Direction not assertedBalancedRhea 43536

L-seryl-[isocitrate dehydrogenase] + ATP = O-phospho-L-seryl-[isocitrate dehydrogenase] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 43540

tyramine + L-glutamate + ATP = gamma-L-glutamyltyramine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 43544

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate

ReversibleBalancedRhea 43548

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate

Left to rightBalancedRhea 43552

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate

Left to rightBalancedRhea 43556

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate

Left to rightBalancedRhea 43560

4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine = [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate

Direction not assertedBalancedRhea 43564

3,6-anhydro-alpha-L-galactopyranose + NAD(+) + H2O = 3,6-anhydro-L-galactonate + NADH + 2 H(+)

Direction not assertedBalancedRhea 43568

D-arginine + A + H2O = 5-guanidino-2-oxopentanoate + AH2 + NH4(+)

Direction not assertedBalancedRhea 43572

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + phosphate

Direction not assertedBalancedRhea 43576

D-arginine + A = iminoarginine + AH2

Direction not assertedBalancedRhea 43580

iminoarginine + H2O = 5-guanidino-2-oxopentanoate + NH4(+)

Direction not assertedBalancedRhea 43584

a globoside NORint + UDP-alpha-D-galactose = a globoside NOR2 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 43588

all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-8'-apo-beta-carotenal + 3beta-hydroxy-beta-cyclocitral

Direction not assertedBalancedRhea 43592

(3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = crocetin dialdehyde + 3beta-hydroxy-beta-cyclocitral

Direction not assertedBalancedRhea 43596

3-oxoeicosanoyl-[ACP] + NADPH + H(+) = 3R-hydroxyeicosanoyl-[ACP] + NADP(+)

Direction not assertedBalance undeterminableRhea 43600

(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + oxidized [flavodoxin] + H2O + 2 H(+) = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]

Direction not assertedBalance undeterminableRhea 43604

cytidine(34) in tRNA(Ile2) + agmatine + ATP + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 43608

uridine(341) in tmRNA + S-adenosyl-L-methionine = 5-methyluridine(341) in tmRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 43612

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