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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,801–7,850 of 18,558 reactions from Rhea

a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + (24S)-hydroxycholesterol = (24S)-24-hydroxycholesterol ester + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Left to rightBalance undeterminableRhea 43216
guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 43220
(24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine = (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Left to rightBalancedRhea 43224
L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalance undeterminableRhea 43228
isatin + H2O = isatinate + H(+)
Direction not assertedBalancedRhea 43232
1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate
Left to right

→

Balanced

Rhea 43236

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43240

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43244

1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O = 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate

Left to rightBalancedRhea 43248

1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43252

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43256

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43260

eicosanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 43264

a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + UDP + H(+)

Left to rightBalance undeterminableRhea 43268

a ganglioside GD3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 + UDP + H(+)

Left to rightBalance undeterminableRhea 43272

a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + UDP + H(+)

Left to rightBalance undeterminableRhea 43276

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43280

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43284

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate

Left to rightBalancedRhea 43288

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43292

1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 43296

a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + UDP + H(+)

Left to rightBalance undeterminableRhea 43300

a beta-D-Gal-(1<->1')-ceramide + 3'-phosphoadenylyl sulfate = 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 43304

1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 43308

N-(hexanoyl)sphing-4-enine + ATP = N-hexanoylsphing-4-enine 1-phosphate + ADP + H(+)

Left to rightBalancedRhea 43312

2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 43316

1-(9Z-octadecenoyl)-2-acyl-sn-3-glycerol + a sphingomyelin = a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine

ReversibleBalance undeterminableRhea 43320

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine = 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin

ReversibleBalance undeterminableRhea 43324

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 43328

adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 43332

N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) + H(+) = N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out) + CO2

Direction not assertedBalance undeterminableTransportRhea 43336

[ThiS sulfur-carrier protein]-C-terminal Gly-Gly-AMP + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 = [ThiS sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + L-cysteinyl-[cysteine desulfurase] + A + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 43340

[ThiS sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [ThiS sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate

Direction not assertedBalance undeterminableRhea 43344

cholesteryl (9Z-octadecenoate)(in) = cholesteryl (9Z-octadecenoate)(out)

Direction not assertedBalancedTransportRhea 43348

1,2,3-tri-(9Z-octadecenoyl)-glycerol(in) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol(out)

Direction not assertedBalancedTransportRhea 43352

cholesteryl (9Z,12Z)-octadecadienoate(in) = cholesteryl (9Z,12Z)-octadecadienoate(out)

Direction not assertedBalancedTransportRhea 43356

an N-acylsphinganine + UDP-alpha-D-glucose = an N-acyl-beta-D-glucosyl-(1<->1')-sphinganine + UDP + H(+)

Direction not assertedBalance undeterminableRhea 43360

L-erythro-N-acylsphing-4-enine + UDP-alpha-D-glucose = beta-D-glucosyl-L-erythro-N-acylsphing-4-enine + UDP + H(+)

Direction not assertedBalance undeterminableRhea 43364

dodecanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA

Direction not assertedBalancedRhea 43368

dTDP-alpha-D-glucose + an N-acylsphing-4-enine = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + dTDP + H(+)

Direction not assertedBalance undeterminableRhea 43372

5'-deoxyinosine + phosphate = 5-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine

Direction not assertedBalancedRhea 43376

N(omega)-phospho-L-arginyl-[protein] + H2O = L-arginyl-[protein] + phosphate

Direction not assertedBalance undeterminableRhea 43380

L-arginyl-[protein] + ATP = N(omega)-phospho-L-arginyl-[protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 43384

1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate

Left to rightBalancedRhea 43388

1D-myo-inositol 1,3,4-trisphosphate + H2O = 1D-myo-inositol 1,3-bisphosphate + phosphate

Left to rightBalancedRhea 43392

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate) + ADP + H(+)

Left to rightBalancedRhea 43396

N-(2-hydroxy-hexanoyl)-sphing-4-enine + UDP-alpha-D-galactose = N-(2-hydroxy-hexanoyl)-beta-D-galactosyl-sphing-4-enine + UDP + H(+)

Left to rightBalancedRhea 43400

N-(2-hydroxy-hexanoyl)-sphinganine + UDP-alpha-D-galactose = N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine + UDP + H(+)

Left to rightBalancedRhea 43404

sphinganine + UDP-alpha-D-galactose = beta-D-galactosyl-(1<->1')-sphinganine + UDP + H(+)

Direction not assertedBalancedRhea 43408

a D-galactosylceramide + H2O = an N-acyl-sphingoid base + D-galactose

Left to rightBalance undeterminableRhea 43412

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