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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,501–7,550 of 18,558 reactions from Rhea

3beta-hydroxy-5alpha-pregnane-20-one + NAD(+) = 5alpha-pregnane-3,20-dione + NADH + H(+)
Direction not assertedBalancedRhea 41988
17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)
Left to rightBalancedRhea 41992
a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose = a globoside GalGb4Cer (d18:1(4E)) + UDP + H(+)
Left to rightBalance undeterminableRhea 41996
a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = an isogloboside iGb3Cer (d18:1(4E)) + UDP + H(+)
Left to rightBalance undeterminableRhea 42000
5alpha-androstane-3alpha,17beta-diol + NAD(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADH + H(+)
Right to leftBalancedRhea 42004
5alpha-pregnan-20beta-ol-3-one + NAD(+) = 5alpha-pregnane-3,20-dione + NADH + H(+)
Left to rightBalancedRhea 42008

cortisol + NAD(+) = 11beta,17alpha-dihydroxypregn-4-ene-3,20,21-trione + NADH + H(+)

Left to rightBalancedRhea 42012

cortisone + NAD(+) = 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + NADH + H(+)

Left to rightBalancedRhea 42016

11-dehydrocorticosterone + NAD(+) = pregn-4-ene-3,11,20,21-tetraone + NADH + H(+)

Left to rightBalancedRhea 42020

3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + NADH + H(+)

Left to rightBalancedRhea 42024

ursodeoxycholate + NAD(+) = 7-oxolithocholate + NADH + H(+)

Left to rightBalancedRhea 42028

N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2

Left to rightBalance undeterminableRhea 42032

chenodeoxycholate + NAD(+) = 7-oxolithocholate + NADH + H(+)

Left to rightBalancedRhea 42036

a ganglioside GM1 (d18:1(4E)) + GDP-beta-L-fucose = a ganglioside Fuc-GM1 (d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 42040

a globoside GalGb4Cer (d18:1(4E)) + GDP-beta-L-fucose = a globoside Globo-H (d18:1(4E)) + GDP + H(+)

Left to rightBalance undeterminableRhea 42044

3-hydroxybutanoyl-CoA + NAD(+) = acetoacetyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 42048

9-cis-retinol + NAD(+) = 9-cis-retinal + NADH + H(+)

Left to rightBalancedRhea 42052

13-cis-retinol + NAD(+) = 13-cis-retinal + NADH + H(+)

Direction not assertedBalancedRhea 42056

11-cis-retinol + NAD(+) = 11-cis-retinal + NADH + H(+)

Direction not assertedBalancedRhea 42060

GTP + ATP = 2',3'-cGAMP + 2 diphosphate

Left to rightBalancedRhea 42064

(3R,5R)-clavulanate-9-aldehyde + NADPH + H(+) = clavulanate + NADP(+)

Direction not assertedBalancedRhea 42068

(4Z)-2-oxohept-4-enedioate + H2O = (4S)-4-hydroxy-2-oxoheptanedioate

Direction not assertedBalancedRhea 42072

2-hydroxyglutarate + acetyl-CoA = 2-hydroxyglutaryl-CoA + acetate

Direction not assertedBalancedRhea 42076

all-trans-retinal + NAD(+) + H2O = all-trans-retinoate + NADH + 2 H(+)

Left to rightBalancedRhea 42080

9-cis-retinal + NAD(+) + H2O = 9-cis-retinoate + NADH + 2 H(+)

Left to rightBalancedRhea 42084

all-trans-retinal + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-retinoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 42088

all-trans-retinol + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-retinal + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 42092

tobramycin + carbamoyl phosphate + ATP + H2O = nebramycin 5' + AMP + phosphate + diphosphate + H(+)

Direction not assertedBalancedRhea 42096

kanamycin A + carbamoyl phosphate + ATP + H2O = 6''-O-carbamoylkanamycin A + AMP + phosphate + diphosphate + H(+)

Direction not assertedBalancedRhea 42100

(20S)-hydroxypregn-4-en-3-one + NAD(+) = progesterone + NADH + H(+)

Direction not assertedBalancedRhea 42108

(20S)-hydroxypregn-4-en-3-one + NADP(+) = progesterone + NADPH + H(+)

Right to leftBalancedRhea 42112

5alpha-androstane-3alpha,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+)

Right to leftBalancedRhea 42116

17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = 5alpha-androstan-3,17-dione + NADPH + H(+)

Right to leftBalancedRhea 42120

5alpha-androstane-3alpha,17beta-diol + NAD(+) = androsterone + NADH + H(+)

Direction not assertedBalancedRhea 42124

N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42128

isonocardicin C = nocardicin C

Direction not assertedBalancedRhea 42132

an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42136

N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

ReversibleBalance undeterminableRhea 42140

N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42144

an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Left to rightBalance undeterminableRhea 42148

an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol

ReversibleBalance undeterminableRhea 42152

androsterone + NADPH + H(+) = 5alpha-androstane-3alpha,17beta-diol + NADP(+)

Left to rightBalancedRhea 42156

(11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42160

(11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42164

20alpha-hydroxy-5beta-pregnan-3-one + NADP(+) = 5beta-pregnan-3,20-dione + NADPH + H(+)

Right to leftBalancedRhea 42168

(11Z)-eicosenoyl-CoA + AH2 + O2 = (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 42172

(9Z)-tetradecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z,12Z)-tetradecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42176

(6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 42180

5alpha-androstane-3beta,17beta-diol + NAD(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADH + H(+)

Right to leftBalancedRhea 42184

3beta-hydroxy-5alpha-androstan-17-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)

Right to leftBalancedRhea 42188

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