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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
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Interactions
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Reactions
Reach

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Processes
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Cell types
Organisms
Materials
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Diseases

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

7,451–7,500 of 18,558 reactions from Rhea

holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA
Left to rightBalance undeterminableRhea 41788
holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA
Left to rightBalance undeterminableRhea 41792
N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
ReversibleBalance undeterminableRhea 41796
acetyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxobutanoyl-[ACP] + holo-[ACP] + CO2
Left to rightBalance undeterminableRhea 41800
3-oxobutanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxybutanoyl-[ACP] + NADP(+)
Left to rightBalance undeterminableRhea 41804
(3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O
Left to rightBalance undeterminableRhea 41808
(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41812

a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 41816

butanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41820

3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41824

(3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41828

(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41832

hexanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41836

3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41840

(3R)-hydroxyoctanoyl-[ACP] = (2E)-octenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41844

(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41848

octanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41852

3-oxodecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41856

(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41860

(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41864

decanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41868

3-oxododecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydodecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41872

(3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41876

(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41880

dodecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41884

3-oxotetradecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxytetradecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41888

(3R)-hydroxytetradecanoyl-[ACP] = (2E)-tetradecenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41892

(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41896

tetradecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexadecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41900

3-oxohexadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41904

(3R)-hydroxyhexadecanoyl-[ACP] = (2E)-hexadecenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41908

(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41912

hexadecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2

Left to rightBalance undeterminableRhea 41916

3-oxooctadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41920

(3R)-hydroxyoctadecanoyl-[ACP] = (2E)-octadecenoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 41924

(2E)-octadecenoyl-[ACP] + NADPH + H(+) = octadecanoyl-[ACP] + NADP(+)

Left to rightBalance undeterminableRhea 41928

hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+)

Left to rightBalance undeterminableRhea 41932

a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 41936

[amino-group carrier protein]-C-terminal-L-glutamate + L-2-aminoadipate + ATP = [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 41940

[amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ATP = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + ADP

Direction not assertedBalance undeterminableRhea 41944

[amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + phosphate + NADP(+) = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 41948

[amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + 2-oxoglutarate = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + L-glutamate

Direction not assertedBalance undeterminableRhea 41952

2',3'-cyclophospho-CMP + H2O = cytidine 2'-phosphate + H(+)

Direction not assertedBalancedRhea 41956

a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 41960

butanoyl-CoA + O2 = (2E)-butenoyl-CoA + H2O2

Direction not assertedBalancedRhea 41964

a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41968

a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41972

a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 41976

3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) = 5alpha-pregnane-3,20-dione + NADH + H(+)

Left to rightBalancedRhea 41980

propan-2-ol + NAD(+) = acetone + NADH + H(+)

Direction not assertedBalancedRhea 41984

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