Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

701–750 of 18,558 reactions from Rhea

acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)
Direction not assertedBalancedRhea 12929
L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate
Direction not assertedBalancedRhea 12933
a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
Left to rightBalance undeterminableRhea 12937
an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 12941
2'-hydroxybiphenyl-2-sulfinate + H2O = biphenyl-2-ol + sulfite + H(+)
Direction not assertedBalancedRhea 12945
D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H2O
Direction not asserted

Balanced

Rhea 12949

L-seryl-[Goodpasture antigen-binding protein] + ATP = O-phospho-L-seryl-[Goodpasture antigen-binding protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 12953

an acetyl ester + H2O = an aliphatic alcohol + acetate + H(+)

Left to rightBalance undeterminableRhea 12957

acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate

Direction not assertedBalancedRhea 12961

D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + H(+)

Direction not assertedBalancedRhea 12965

a sn-glycero-3-phosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate + H(+)

Direction not assertedBalance undeterminableRhea 12969

AMP + ATP = 2 ADP

Direction not assertedBalancedRhea 12973

N-phosphocreatine + H2O = creatine + phosphate

Left to rightBalancedRhea 12977

S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)

Direction not assertedBalancedRhea 12981

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + GDP-beta-L-fucose = an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc}-L-asparaginyl-[protein] + GDP + H(+)

Left to rightBalance undeterminableRhea 12985

a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + H2O = D-mannose + a di-trans,poly-cis-dolichyl phosphate + H(+)

Direction not assertedBalance undeterminableRhea 12989

cyclohex-1-ene-1-carbonyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = cyclohexa-1,5-diene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 12993

galactarate + (E)-feruloyl-CoA = 2-O-[(E)-feruloyl]-D-galactarate + CoA

Direction not assertedBalancedRhea 12997

1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate

Direction not assertedBalancedRhea 13001

(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine = N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 13005

N-formyl-L-kynurenine + H2O = L-kynurenine + formate + H(+)

Direction not assertedBalancedRhea 13009

a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose = an alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)

Left to rightBalance undeterminableRhea 13013

UMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + uracil

Direction not assertedBalancedRhea 13017

vanillate + NADH + O2 + H(+) = 3,4-dihydroxybenzoate + formaldehyde + NAD(+) + H2O

Direction not assertedBalancedRhea 13021

3-methylbut-2-enoyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = 3-methyl-(2E)-glutaconyl-CoA + N(6)-biotinyl-L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 13025

N-acetyl-D-glucosamine + O2 + H2O = N-acetyl-D-glucosaminate + H2O2 + H(+)

Direction not assertedBalancedRhea 13029

aldehydo-D-galactose 6-phosphate = keto-D-tagatose 6-phosphate

Direction not assertedBalancedRhea 13033

ATP + H2O + H(+) = ITP + NH4(+)

Direction not assertedBalancedRhea 13037

L-dopachrome = 5,6-dihydroxyindole-2-carboxylate

Direction not assertedBalancedRhea 13041

ent-kaur-16-ene + reduced [NADPH--hemoprotein reductase] + O2 = ent-kaur-16-en-19-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 13045

D-glucuronate = D-fructuronate

Direction not assertedBalancedRhea 13049

L-phenylalanine + pyruvate = 3-phenylpyruvate + L-alanine

Direction not assertedBalancedRhea 13053

an N-acylneuraminate 9-phosphate + H2O = an N-acylneuraminate + phosphate

Direction not assertedBalance undeterminableRhea 13057

S-sulfanylglutathione + O2 = glutathione S,S-dioxide + H(+)

Direction not assertedBalancedRhea 13061

ATP + H2O = ADP + phosphate + H(+)

Left to rightBalancedRhea 13065

ethanolamine + ATP = phosphoethanolamine + ADP + H(+)

Left to rightBalancedRhea 13069

guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate + H(+)

Direction not assertedBalancedRhea 13073

a D-hexose + an acyl phosphate = a D-hexose phosphate + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 13077

biotin amide + H2O = biotin + NH4(+)

Left to rightBalancedRhea 13081

(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6-oxoheptanedioate + CoA

Direction not assertedBalancedRhea 13085

6 Fe(III)-[cytochrome c] + NH4(+) + 2 H2O = 6 Fe(II)-[cytochrome c] + nitrite + 8 H(+)

Direction not assertedBalance undeterminableRhea 13089

an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)

Left to rightBalance undeterminableRhea 13093

a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 13097

4-imidazolone-5-propanoate = trans-urocanate + H2O

Direction not assertedBalancedRhea 13101

glycerol 2-phosphate + H2O = glycerol + phosphate

Left to rightBalancedRhea 13105

2-acetamidofluorene + NAD(+) + H2O = N-hydroxy-2-acetamidofluorene + NADH + H(+)

Direction not assertedBalancedRhea 13109

2-acetamidofluorene + NADP(+) + H2O = N-hydroxy-2-acetamidofluorene + NADPH + H(+)

Direction not assertedBalancedRhea 13113

pyrazole + O-acetyl-L-serine = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)

Direction not assertedBalancedRhea 13117

shikimate + ATP = 3-phosphoshikimate + ADP + H(+)

Direction not assertedBalancedRhea 13121

glutathione disulfide + CoA = CoA-glutathione + glutathione

Direction not assertedBalancedRhea 13125

Page 15 of 372